by Rod Pearson
Friday, Nov 13, 2026
Game Time: 4:05 pm ET, Sunday, November 15, 2026
Venue: State Farm Stadium, Glendale, AZ
Where to Watch: CBS
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: Rams -9.5, Cardinals +9.5; Over/Under: 39.5 points
Bet365: Point Spread: Rams -9.5, Cardinals +9.5; Over/Under: 39.5 points
BetMGM: Point Spread: Rams -9.5, Cardinals +9.5; Over/Under: 39.5 points
Season Record
Los Angeles Rams: 5-4 (3rd place, NFC West)
Arizona Cardinals: 3-6 (4th place, NFC West)
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Recent Form
Los Angeles Rams: won their last game on the road against the Washington Commanders 20-13.
Arizona Cardinals: lost their last game on the road against the Seattle Seahawks 17-3.
Los Angeles Rams vs Arizona Cardinals Preview and Analysis
The Rams are entering this game with a 5-4 record overall and they have a 0-2 record in their divisional games too. They are 2-2 in their home games, 3-1 in their road games, and they are also 0-1 in their neutral site games this season, but they will be on the road for this game. They won their last game against the Washington Commanders 20-13. Matthew Stafford was the starting QB and he completed 26/43 passes for 228 passing yards, 1 touchdown, and 1 interception. Blake Corum led the team in rushing yards with 58 and 1 TD. Puka Nacua led the receivers with 150 receiving yards on 14 receptions and 1 TD. Kamren Curl led the defense in that game with 8 solo tackles while Myles Garrett led the defense in sacks with 3. No one on the defense came away with an interception for them in that one.
The Cardinals are entering this game with a 3-6 record overall and they have a 1-3 record in their divisional games too. They are 0-3 in their home games, 3-3 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They lost their last game against the Seattle Seahawks 17-3. Gardner Minshew II was the starting QB and he completed 21/30 passes for 166 passing yards, 0 touchdowns, and 0 interceptions. Tyler Allgeier led the team in rushing yards with 46. Michael Wilson led the receivers with 60 receiving yards on 6 receptions. Andrew Wingard led the defense in that game with 12 solo tackles while no one on the defense recorded a sack for them. No one on the defense came away with an interception for them in that one.
Rams vs Cardinals Prediction
The current betting odds have the Rams listed as a 9.5 point favorite in this game according to Draftkings Sportsbook. The Rams have looked good in their games this season with their 5-4 record overall, but that record has them right near the bottom of the NFC West. They have been a good road team though with their 3-1 road record this year. Meanwhile, the Cardinals haven't looked good in their games this season with their 3-6 record overall which has them right at the bottom of the NFC West. They have looked terrible on their home field too with their 0-3 home record this season. The Cardinals have been really up and down this season with their new head coach, but they were supposed to be the worst team in the NFL and have definitely looked a lot better than that. They are too inconsistent from week to week though and now they are dealing with a ton of injuries, also starting Carson Beck in his NFL debut here. They do have a win over the Rams 18-16, but they are coming off a 17-3 loss to the Seahawks in their last one and the Rams aren't going to let the Cardinals get away with another win. The Rams didn't have a great start to the season, but they have looked a lot better lately and can't afford to lose anymore stupid games with the strength of the NFC. They are also banged up on offense, but they have enough talent to get by here and the defense has been getting healthier too. They are coming off a 20-13 win over the Commanders in their last one, starting to build some momentum now, and they are going to bring a little extra here to get the Cardinals back. The best way to place a bet here is on the Rams to cover the spread in this game.
Rams Cardinals Prediction: Our NFL Pick for Sunday, November 15, 2026 (4:05 pm ET start time) is Rams 35 Cardinals 13.
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NFL Betting Trends
Los Angeles Rams: 11-5 ATS as a road favorite. 9-3 ATS after allowing 14 points or less last game. 9-5 ATS vs. bad defensive teams who give up 24 or more points/game. 16-8 OVER in road games. 4-0 OVER in all games where the total is between 35.5 and 42 points.
Arizona Cardinals: 4-9 ATS as a home underdog. 4-9 ATS after playing a division game. 7-14 ATS after playing their last game on the road. 9-2 OVER after playing a division game. 12-5 OVER when playing against a team with a winning record.
Key Injuries
Los Angeles Rams: T. Higbee (TE) Injured - Illness. M. Stafford (QB) Injured - Elbow. M. Garrett (LB) Injured - Knee. J. Cardona (LS) Injured - Ankle. K. Curl (S) Injured - Toe. C. Parkinson (TE) Injured - Ribs. S. Avila (OG) Injured - Hamstring. D. Allen (TE) Injured - Oblique. T. McDuffie (CB) Injured - Back. T. Ferguson (TE) Injured - Ankle.
Arizona Cardinals: D. Robinson (DL) Injured - Wrist. B. Baker (S) Injured - Rest. I. Seumalo (OG) Injured - Rest. H. Froholdt (OG) Injured - Concussion. M. Wilson Sr. (LB) Injured - Rest. J. Sweat (LB) Injured - Rest. H. Long (TE) Injured - Knee. Z. Carter (DL) Injured - Knee. R. Lopez (DL) Injured - Toe. A. Wingard (S) Injured - Groin. J. Gaines II (OG) Injured - Ankle. D. Stills (DL) Injured - Shoulder. B. Knight (RB) Injured - Concussion. M. Melton (CB) Injured - Knee. J. Williams (OG) Injured - Knee.
Notable Quotes
“I thought our guys did a great job of being able to find a way. There was a lot of opportunities that we missed offensively to make plays, extend drives, but they did enough. I love the way that Matthew responded after the turnover where he leads us down the field — had a bunch of gutsy conversions.” - Sean McVay after his team’s win against the Commanders in their last game.
“We were a little bit off one way or another on a lot of our plays, and against a good team like that, you’re not going to have that many chances.” - Gardner Minshew after their loss against the Seahawks in their last game.
Starting Lineups
Los Angeles Rams
WR Daniels, CJ
WR Atwell, Tutu
WR Mumpfield, Konata
TE Higbee, Tyler
QB Stafford, Matthew
RB Williams, Kyren
Arizona Cardinals
WR Fehoko, Simi
WR Virgil, Reggie
WR Duvernay, Devin
TE McBride, Trey
QB Beck, Carson
RB Allgeier, Tyler
Statistical Leaders
Los Angeles Rams
Passing: Matthew Stafford (2,374)
Rushing: Kyren Williams (593)
Receiving: Puka Nacua (715)
Touchdowns: Kyren Williams (7)
Arizona Cardinals
Passing: Jacoby Brissett (1,719)
Rushing: Tyler Allgeier (369)
Receiving: Trey McBride (598)
Touchdowns: Trey McBride (5)
Coaches:
Los Angeles Rams: Sean McVay (10th season)
Arizona Cardinals: Mike LaFleur (1st season)
Rod Pearson
About the Author:
Rod Pearson has been a rabid sports fan his entire life. He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years. In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective. Join Rod every day as he breaks down the games to find the best betting value.
