by Rod Pearson
Friday, Jun 26, 2026
Game Time: 8:40 pm ET, Saturday, June 27, 2026
Venue: Petco Park, San Diego, CA
Where to Watch: MLB TV, MLB Network
Opening Odds at USA Sportsbooks
DraftKings: Moneyline odds: Dodgers -199, Padres +163; Over/Under: 7.5 runs
Bet365: Moneyline odds: Dodgers -200, Padres +165; Over/Under: 7.5 runs
BetMGM: Moneyline odds: Dodgers -200, Padres +165; Over/Under: 7.5 runs
Season Record
Los Angeles Dodgers: 52-29 (1st place, NL West)
San Diego Padres: 42-37 (2nd place, NL West)
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Recent Form
Los Angeles Dodgers: 7-3 last 10
San Diego Padres: 6-4 last 10
Los Angeles Dodgers vs San Diego Padres Preview and Analysis
The Dodgers are entering this series off a win and completed the sweep in their 3-game series against the Minnesota Twins 3-0 in their last series. They enter this game with a 52-29 record overall and have a road record of 26-15. This is the 2nd game of a 3-game series with the Padres on Saturday with the series opener still to be played on Friday. Their offense ranks 1st in the MLB with a .783 OPS. Roki Sasaki is their starting pitcher on Friday while Yoshinobu Yamamoto is making his start in this game on Saturday. He is 7-5 with a 2.65 ERA this season. His team won 4 of their last 5 games this season with him making an appearance. In his last MLB regular season appearance, he allowed 3 ER, 0 HR, and 2 BB with 6 SO on 6 hits through 6 IP against the Baltimore Orioles.
The Padres are entering this series off a win and completed the sweep in their 3-game series against the Atlanta Braves 3-0 in their last series. They enter this game with a 42-37 record overall and have a home record of 22-19. This is the 2nd game of a 3-game series with the Dodgers on Saturday with the 1st game of this series still to be played on Friday. Their offense ranks 30th in the MLB with a .658 OPS. Walker Buehler is their starting pitcher on Friday while Randy Vásquez is making his start in this game on Saturday. He is 6-5 with a 4.17 ERA this season. His team lost 5 of their last 6 games this season with him making an appearance. In his last MLB regular season start, he allowed 6 earned runs, 0 homers, and 3 walks with 1 strikeout on 8 hits through 3.1 innings pitched against the Texas Rangers.
Dodgers vs Padres Prediction
The current betting odds have the Dodgers listed as a big favorite in this game according to Draftkings Sportsbook. The Padres have looked good in their games this season with their 42-37 record overall which has them right near the top of the NL West. They have looked good in their own ballpark too with their 22-19 home record this season. Meanwhile, the Dodgers have looked great in their games this season with their 52-29 record overall which has them right at the top of the NL West with one of the best records in MLB. They have been a great road team too with their 26-15 road record this year. The Padres are 6-4 in their last 10 games and have looked good lately, sweeping the Braves in their last series, but the Dodgers are also coming off a sweep and have still been the hotter team, going 7-3 in their last 10 games. The Dodgers also have one of the best offenses in MLB this season while the Padres have one of the worst, and the Dodgers are going to be able to take advantage of this pitching matchup. Yamamoto is on the mound for the Dodgers in this one and he has looked good this season. He is 7-5 with a 2.65 ERA and the team has been having a lot of success with him lately. He is coming off a start in which he gave up 3 earned runs, but that hasn't been a common theme for him this year and the team has won 4 of their last 5 games with him starting. Vasquez is on the mound for the Padres in this one and he hasn't looked great this season. He is 6-5 with a 4.17 ERA and had a great start to the year, but lately he hasn't looked as good. He is coming off a terrible start in which he gave up 6 earned runs which has been becoming a common theme for him lately, and even his team has lost 5 of their last 6 games with him starting. All signs point to the Dodgers continuing to roll in this one. The best way to place a bet here is on the Dodgers to win this game and on the runline.
Dodgers Padres Prediction: Our MLB Pick for Saturday, June 27, 2026 (8:40 pm ET start time) is Dodgers 8 Padres 3.
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MLB Betting Trends
Los Angeles Dodgers: 267-171 (-10.3 units) on the moneyline in all games. 240-138 (-6.8 units) on the moneyline as a favorite of -110 or higher. 185-122 (-12.2 units) on the moneyline against right-handed starters. 11-2 UNDER when the total is 7 to 7.5.
San Diego Padres: 231-183 (+26.2 units) on the moneyline in all games. 122-85 (+9.6 units) on the moneyline in home games. 86-81 (+27.8 units) on the moneyline as an underdog of +100 or higher. 9-5 UNDER as a home underdog of +100 or higher.
Key Injuries
Los Angeles Dodgers: K. Tucker (RF) Day To Day - Back. B. Treinen (RP) Fifteen Day IL - Elbow. W. Smith (C) Ten Day IL - Neck. B. Graterol (RP) Sixty Day IL - Shoulder. T. Hernandez (LF) Ten Day IL - Hamstring. B. Snell (SP) Sixty Day IL - Elbow. E. Hernandez (1B) Ten Day IL - Oblique. B. Casparius (RP) Sixty Day IL - Shoulder. E. Diaz (RP) Sixty Day IL - Elbow. T. Glasnow (SP) Sixty Day IL - Back. L. Knack (SP) Sixty Day IL - Chest. J. Cousins (RP) Sixty Day IL - Elbow. G. Stone (SP) Sixty Day IL - Shoulder. B. Miller (SP) Sixty Day IL - Shoulder. E. Phillips (RP) Sixty Day IL - Elbow.
San Diego Padres: L. Giolito (SP) Fifteen Day IL - Elbow. J. Estrada (RP) Fifteen Day IL - Knee. R. Laureano (LF) Sixty Day IL - Hip. N. Pivetta (SP) Sixty Day IL - Elbow. L. Campusano (C) Ten Day IL - Toe. M. Waldron (SP) Fifteen Day IL - Arm. J. Cronenworth (2B) Seven Day IL - Concussion. G. Marquez (SP) Fifteen Day IL - Forearm. B. Hoeing (RP) Sixty Day IL - Elbow. J. Musgrove (SP) Sixty Day IL - Elbow.
Notable Quotes
"I don't think it was a blow [to his ego]. I actually think it freed [Rushing] up. I think that if there's ever any doubt, the pitcher always has the right of last refusal and can call his own game. So I think once we decided to do that, then it was pretty clean after that." - Dave Roberts on Shohei Ohtani taking over the pitch-calling duties in his team’s win against the Twins in their game on Wednesday.
“The way he threw the ball today is what he’s capable of doing in the big leagues. We needed him big. He stepped up.” - Craig Stammen after his team’s win against the Braves in their game on Wednesday.
Starting Lineups
Los Angeles Dodgers
Shohei Ohtani (L) P
Andy Pages (R) CF
Freddie Freeman (L) 1B
Mookie Betts (R) SS
Max Muncy (L) 3B
Alex Call (R) RF
Ryan Ward (L) LF
Dalton Rushing (L) C
Alex Freeland (S) 2B
San Diego Padres
Fernando Tatis Jr. (R) 2B
Samad Taylor (R) LF
Manny Machado (R) 3B
Xander Bogaerts (R) SS
Jackson Merrill (L) CF
Miguel Andujar (R) DH
Ty France (R) 1B
Freddy Fermin (R) C
Jase Bowen (R) RF
Statistical Leaders
Los Angeles Dodgers
Batting Average: Enrique Hernández (1.000)
Hits: Andy Pages (83)
Home Runs: Shohei Ohtani (17)
RBI: Andy Pages (58)
Stolen Bases: Andy Pages (8)
Wins: Justin Wrobleski (9)
Saves: Tanner Scott (11)
ERA: Charlie Barnes (0.00)
San Diego Padres
Batting Average: Samad Taylor (.379)
Hits: Fernando Tatis (85)
Home Runs: Manny Machado (14)
RBI: Manny Machado (43)
Stolen Bases: Fernando Tatis (19)
Wins: Randy Vásquez (6)
Saves: Mason Miller (21)
ERA: Mason Miller (0.79)
Managers:
Los Angeles Dodgers: Dave Roberts (11th season)
San Diego Padres: Craig Stammen (1st season)
Rod Pearson
About the Author:
Rod Pearson has been a rabid sports fan his entire life. He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years. In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective. Join Rod every day as he breaks down the games to find the best betting value.
