Los Angeles Dodgers vs Pittsburgh Pirates Prediction, Preview and Odds - 06/10/2026

Game Time: 6:40 pm ET, Wednesday, June 10, 2026

Venue:  PNC Park, Pittsburgh, PA 

Where to Watch:  MLB TV

DraftKings:  Moneyline odds:  Dodgers -194, Pirates +159; Over/Under:  8 runs

Bet365:  Moneyline odds:  Dodgers -190, Pirates +160; Over/Under:  7.5 runs

BetMGM:  Moneyline odds:  Dodgers -195, Pirates +160; Over/Under:  7.5 runs

Los Angeles Dodgers:  42-24 (1st place, NL West)

Pittsburgh Pirates:  34-32 (3rd place, NL Central)

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Los Angeles Dodgers:  6-4 last 10

Pittsburgh Pirates:  5-5 last 10

The Dodgers are entering this series off a loss and won their 3-game series against the Los Angeles Angels 2-1 in their last series. They enter this game with a 42-24 record overall and have a road record of 20-12. This is the 2nd game of a 3-game series with the Pirates on Wednesday with the series opener still to be played on Tuesday. Their offense ranks 1st in the MLB with a .784 OPS. Eric Lauer is their starting pitcher on Tuesday while Shohei Ohtani is making his start in this game on Wednesday. He is 6-2 with a 0.74 ERA this season. His team won their last 4 straight games this season with him making an appearance. In his last MLB regular season appearance, he allowed 0 ER, 0 HR, and 1 BB with 6 SO on 2 hits through 6 IP against the Arizona Diamondbacks.

The Pirates are entering this series off a loss and got swept in their 3-game series against the Atlanta Braves 3-0 in their last series. They enter this game with a 34-32 record overall and have a home record of 18-15. This is the 2nd game of a 3-game series with the Dodgers on Wednesday with the 1st game of this series still to be played on Tuesday. Their offense ranks 6th in the MLB with a .735 OPS. Paul Skenes is their starting pitcher on Tuesday while Jared Jones is making his start in this game on Wednesday. He is 1-0 with a 4.82 ERA this season. His team won both games this season with him making an appearance. In his last MLB regular season start, he allowed 0 earned runs, 0 homers, and 2 walks with 4 strikeouts on 4 hits through 5 innings pitched against the Houston Astros.

The current betting odds have the Dodgers listed as a big favorite in this game according to Draftkings Sportsbook. The Pirates have looked good in their games this season with their 34-32 record overall which has them right in the middle of the NL Central. They have looked good in their own ballpark too with their 18-15 home record this season. Meanwhile, the Dodgers have looked great in their games this season with their 42-24 record overall which has them right at the top of the NL West with one of the best records in MLB. They have been a good road team too with their 20-12 road record this year. The Dodgers haven't been rolling lately, but they are still 6-4 in their last 10 games and have one of the best records in MLB right now along with the best offense. The Pirates are only 5-5 in their last 10 games and they have been cooling off from their recent hot streak. They just got swept by the Braves in their last series, another team with one of the best records in the league, and they don't have a great pitching matchup here either. The Pirates are going with Jones in this one and he hasn't looked great this season. He is 1-0 with a 4.82 ERA and hasn't gotten much work this season. He has only pitched in 2 games this year, his team winning both of those, and he was great in his last start since he gave up no runs, but he was also terrible in his 1st start of the season. He is still trying to find his groove in this rotation and this isn't a great game for his 3rd appearance of the season, pitching against one of the best lineups. The Dodgers are also going with Ohtani in this one and he has been a stud this year. He is 6-2 with a 0.74 ERA and he has been shutting teams down. He is off another start in which he gave up no runs, something that has been a common theme for him, and the team has had a ton of success with him starting, winning 4 games in a row now with him on the mound. The Dodgers have the much better offense here and they can take advantage of this pitching matchup. The best way to place a bet here is on the Dodgers to win this game and on the runline. 

Dodgers Pirates Prediction:  Our MLB Pick for Wednesday, June 10, 2026 (6:40 pm ET start time) is Dodgers 8 Pirates 2.

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Los Angeles Dodgers: 41-38 (-17.7 units) on the moneyline against NL Central opponents. 257-166 (-10.3 units) on the moneyline in all games. 146-92 (-37.5 units) on the moneyline as a favorite of -150 or more. 11-1 UNDER when the total is 7 to 7.5.

Pittsburgh Pirates: 43-39 (+14.2 units) on the moneyline as a home underdog of +100 or higher. 18-20 (+3.1 units) on the moneyline vs. an NL team with a slugging percentage of .430 or better on the season. 44-54 (+1.9 units) on the moneyline vs. an NL starting pitcher whose WHIP is 1.250 or better. 34-22 UNDER vs. NL teams allowing 4.0 or less runs/game on the season.

Los Angeles Dodgers:  W. Smith (C) Day To Day - Undisclosed. B. Graterol (RP) Sixty Day IL - Shoulder. T. Hernandez (LF) Ten Day IL - Hamstring. B. Snell (SP) Sixty Day IL - Elbow. E. Hernandez (1B) Ten Day IL - Oblique. B. Casparius (RP) Sixty Day IL - Shoulder. E. Diaz (RP) Sixty Day IL - Elbow. B. Stewart (RP) Fifteen Day IL - Foot. T. Glasnow (SP) Sixty Day IL - Back. L. Knack (SP) Sixty Day IL - Chest. J. Cousins (RP) Sixty Day IL - Elbow. G. Stone (SP) Sixty Day IL - Shoulder. B. Miller (SP) Sixty Day IL - Shoulder. T. Edman (2B) Sixty Day IL - Ankle. E. Phillips (RP) Sixty Day IL - Elbow.

Pittsburgh Pirates:  C. Devenski (RP) Sixty Day IL - Illness. K. Griffin (SS) Ten Day IL - Flexor Tendon. J. Bart (C) Ten Day IL - Foot Infection.

"I just felt right there – to what end? – that I'm not going to put this guy in harm's way with stress. Obviously, the bullpen had to take the toll today, the brunt of it, but with the off-day [Monday], I felt like we could reset. … I love the way that Emmet felt that there was more in the tank, but I wouldn't do that to any of our guys." - Dave Roberts after his team’s loss against the LA Angels in their game on Sunday.

“Really tough loss. Tough series. Again, one hit away. Had opportunities. They got the big hit with guys on, and unfortunately we weren’t able to.” - Don Kelly after his team’s loss against the Braves in their game on Sunday.

Shohei Ohtani (L) DH

Freddie Freeman (L) 1B

Kyle Tucker (L) RF

Max Muncy (L) 3B

Alex Call (R) CF

Dalton Rushing (L) C

Ryan Ward (L) LF

Miguel Rojas (R) SS

Alex Freeland (S) 2B

Spencer Horwitz (L) 1B

Nick Gonzales (R) 2B

Bryan Reynolds (S) LF

Ryan O'Hearn (L) RF

Marcell Ozuna (R) DH

Tyler Callihan (L) 3B

Jake Mangum (S) CF

Jared Triolo (R) SS

Henry Davis (R) C

Batting Average:  Enrique Hernández (1.000)

Hits:  Shohei Ohtani (70)

Home Runs:  Max Muncy (14)

RBI:  Andy Pages (53)

Stolen Bases:  Andy Pages (7)

Wins:  Justin Wrobleski (7)

Saves:  Tanner Scott (6)

ERA:  Charlie Barnes (0.00)

Batting Average:  Nick Gonzales (.309)

Hits:  Nick Gonzales (69)

Home Runs:  Brandon Lowe (15)

RBI:  Oneil Cruz (44)

Stolen Bases:  Oneil Cruz (21)

Wins:  Paul Skenes (6)

Saves:  Gregory Soto (8)

ERA:  Wilber Dotel (1.08)

Managers:

Los Angeles Dodgers: Dave Roberts (11th season)

Pittsburgh Pirates: Don Kelly (2nd season)