Los Angeles Dodgers vs Philadelphia Phillies Prediction, Preview and Odds - 07/22/2026

Game Time: 6:40 pm ET, Wednesday, July 22, 2026

Venue:  Citizens Bank Park, Philadelphia, PA 

Where to Watch:  MLB TV

DraftKings:  Moneyline odds:  Dodgers -110, Phillies -110; Over/Under:  10 runs

Bet365:  Moneyline odds:  Dodgers -110, Phillies -110; Over/Under:  10 runs

BetMGM:  Moneyline odds:  Dodgers -110, Phillies -110; Over/Under:  10 runs

Los Angeles Dodgers:  63-38 (1st place, NL West)

Philadelphia Phillies:  56-45 (2nd place, NL East)

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Los Angeles Dodgers:  4-6 last 10

Philadelphia Phillies:  6-4 last 10

The Dodgers are entering this series off a loss and won their 3-game series against the New York Yankees 2-1 in their last series. They enter this game with a 63-38 record overall and have a road record of 32-19. This is the series finale of a 3-game series with the Phillies on Wednesday with the 2nd game still to be played on Tuesday. The Dodgers lost the series opener on Monday. Their offense ranks 1st in the MLB with a .773 OPS. Justin Wrobleski is their starting pitcher on Tuesday while Eric Lauer is making his start in this game on Wednesday. He is 4-5 with a 4.81 ERA this season. His team won their last 7 straight games this season with him making an appearance. In his last MLB regular season appearance, he allowed 3 ER, 1 HR, and 2 BB with 3 SO on 6 hits through 6 IP against the Colorado Rockies.

The Phillies are entering this series off a loss and lost their 3-game series against the New York Mets 2-1 in their last series. They enter this game with a 56-45 record overall and have a home record of 27-23. This is the 3rd game of a 3-game series with the Dodgers on Wednesday with the 2nd game of this series still to be played on Tuesday. The Phillies won the 1st game of this series on Monday. Their offense ranks 22nd in the MLB with a .707 OPS. Zack Wheeler is their starting pitcher on Tuesday while Aaron Nola is making his start in this game on Wednesday. He is 3-7 with a 5.68 ERA this season. His team lost their last 4 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 3 earned runs, 3 homers, and 4 walks with 6 strikeouts on 6 hits through 6 innings pitched against the New York Mets.

The current betting odds have the Dodgers listed as a pick 'em in this game according to Draftkings Sportsbook. The Phillies have looked good in their games this season with their 56-45 record overall which has them right near the top of the NL East. They have looked good in their own ballpark too with their 27-23 home record this year. Meanwhile, the Dodgers have looked great in their games this season with their 63-38 record overall which has them right at the top of the NL West with one of the best records in MLB. They have been a great road team too with their 32-19 road record this year. The Phillies are 6-4 in their last 10 games and have looked a lot better lately while the Dodgers are 4-6 in their last 10 games and haven't been at their best. The Dodgers do have one of the best offenses in MLB though and this is a pitching matchup that they are going to be able to take advantage of. Lauer is on the mound for the Dodgers in this one and he hasn't looked great this season. He is 4-5 with a 4.81 ERA and is on his 2nd team of the season, but he has looked a lot better since joining the Dodgers and the team has had a ton of success with him too. He did give up 3 earned runs in his last start, but he hasn't been giving up as many runs since joining the Dodgers, and the team has won 7 games in a row now with him starting. The Phillies are going with Nola in this one and he hasn't looked good this season either. He is 3-7 with a 5.68 ERA and the team has been having a lot of trouble with him lately. He is coming off a start in which he gave up 3 earned runs which has been a common theme for him this year, and the team has lost 4 games in a row now with him starting too. Look for the Dodgers to take advantage of this pitching matchup with one of the weaker starters for the Phillies on the mound. The best way to place a bet here is on the Dodgers to win this game. 

Dodgers Phillies Prediction:  Our MLB Pick for Wednesday, July 22, 2026 (6:40 pm ET start time) is Dodgers 8 Phillies 4.

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Los Angeles Dodgers: 278-180 (-16.9 units) on the moneyline in all games. 191-126 (-15 units) on the moneyline against right-handed starters. 139-96 (-25.4 units) on the moneyline vs. an NL team with a team batting average of .255 or worse. 20-12 UNDER when the money line is -100 to -150.

Philadelphia Phillies: 61-34 (+18.3 units) on the moneyline against NL West opponents. 250-184 (+11.6 units) on the moneyline in all games. 138-79 (+21.8 units) on the moneyline in home games. 16-9 UNDER against NL West opponents.

Los Angeles Dodgers:  S. Halvorsen (RP) Fifteen Day IL - Shoulder. B. Treinen (RP) Fifteen Day IL - Elbow. W. Smith (C) Ten Day IL - Neck. B. Graterol (RP) Sixty Day IL - Shoulder. B. Snell (SP) Sixty Day IL - Elbow. E. Hernandez (1B) Ten Day IL - Oblique. B. Casparius (RP) Sixty Day IL - Shoulder. E. Diaz (RP) Sixty Day IL - Elbow. T. Glasnow (SP) Sixty Day IL - Back. J. Cousins (RP) Sixty Day IL - Elbow. G. Stone (SP) Sixty Day IL - Shoulder. B. Miller (SP) Sixty Day IL - Shoulder.

Philadelphia Phillies:  B. Keller (RP) Fifteen Day IL - Elbow. T. Banks (RP) Fifteen Day IL - Forearm. L. Trivino III (RP) Fifteen Day IL - Back. J. Rojas (CF) Sixty Day IL - Elbow. A. Garcia (RF) Sixty Day IL - Lat.

"That was certainly a nice silver lining for tonight. All of his at-bats were really good. I just saw that fire tonight. The good conviction in the swings." - Dave Roberts on Mookie Betts after his team’s loss against the Phillies in their game on Monday. 

“Trea’s our guy. Trea works every day, so it's not like Trea’s out there and he doesn't care about defense. Trea cares about his defense. He wants to make plays. He's working every day, so we ride with Trea.” - Don Mattingly after his team’s win against the LA Dodgers in their game on Monday. 

Shohei Ohtani (L) DH

Andy Pages (R) CF

Tommy Edman (S) 3B

Freddie Freeman (L) 1B

Mookie Betts (R) SS

Miguel Rojas (R) 2B

Teoscar Hernández (R) LF

Alex Call (R) RF

Dalton Rushing (L) C

Trea Turner (R) SS

Kyle Schwarber (L) DH

Bryce Harper (L) 1B

Alec Bohm (R) 3B

Brandon Marsh (L) LF

Bryson Stott (L) 2B

J.T. Realmuto (R) C

Gabriel Rincones Jr. (L) RF

Justin Crawford (L) CF

Batting Average:  Enrique Hernández (1.000)

Hits:  Freddie Freeman (105)

Home Runs:  Shohei Ohtani (22)

RBI:  Andy Pages (68)

Stolen Bases:  Andy Pages (8)

Wins:  Justin Wrobleski (10)

Saves:  Tanner Scott (14)

ERA:  Shohei Ohtani (1.79)

Batting Average:  Derek Hill (.316)

Hits:  Brandon Marsh (104)

Home Runs:  Kyle Schwarber (33)

RBI:  Kyle Schwarber (61)

Stolen Bases:  Trea Turner (17)

Wins:  Cristopher Sánchez (12)

Saves:  Jhoan Duran (24)

ERA:  Bryse Wilson (0.00)

Managers:

Los Angeles Dodgers: Dave Roberts (11th season)

Philadelphia Phillies: Don Mattingly (Interim)