by Rod Pearson
Friday, Oct 23, 2026
Game Time: 8:20 pm ET, Sunday, October 25, 2026
Venue: Lumen Field, Seattle, WA
Where to Watch: NBC
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: Chiefs +3, Seahawks -3; Over/Under: 42.5 points
Bet365: Point Spread: Chiefs +3, Seahawks -3; Over/Under: 42.5 points
BetMGM: Point Spread: Chiefs +2.5, Seahawks -2.5; Over/Under: 42.5 points
Season Record
Kansas City Chiefs: 5-0 (1st place, AFC West)
Seattle Seahawks: 3-3 (2nd place, NFC West)
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Kansas City Chiefs: won their last game at home against the Los Angeles Chargers 22-6.
Seattle Seahawks: lost their last game on the road against the Denver Broncos 17-14 in overtime.
Kansas City Chiefs vs Seattle Seahawks Preview and Analysis
The Chiefs are entering this game with a 5-0 record overall and they have a 3-0 record in their divisional games too. They are 3-0 in their home games, 2-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against the Los Angeles Chargers 22-6. Patrick Mahomes was the starting QB and he completed 23/30 passes for 272 passing yards, 0 touchdowns, and 1 interception. Kenneth Walker III led the team in rushing yards with 128 and 2 TDs. Xavier Worthy led the receivers with 73 receiving yards on 7 receptions. Nick Bolton led the defense in that game with 11 solo tackles while George Karlaftis, Chamarri Conner, and Ashton Gillotte each led the defense in sacks with 1. Jack Cochrane came away with the only interception for them in that one.
The Seahawks are entering this game with a 3-3 record overall and they have a 1-1 record in their divisional games too. They are 2-1 in their home games, 1-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They lost their last game against the Denver Broncos 17-14 in OT. Sam Darnold was the starting QB and he completed 27/51 passes for 278 passing yards, 0 touchdowns, and 2 interceptions. Emanuel Wilson led the team in rushing yards with 52. Jaxon Smith-Njigba led the receivers with 134 receiving yards on 12 receptions. Ernest Jones IV led the defense in that game with 9 solo tackles while Ernest Jones IV and Nick Emmanwori each led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.
Chiefs vs Seahawks Prediction
The current betting odds have the Chiefs listed as a 3 point underdog in this game according to Draftkings Sportsbook. The Chiefs have looked great in their games this season with their 5-0 record overall which has them right at the top of the AFC West. They have been a great road team too with their 2-0 road record this year. Meanwhile, the Seahawks haven't looked great in their games this season with their 3-3 record overall, but that record has them right near the top of the NFC West. They have looked good on their home field too with their 2-1 home record this season. The Seahawks are the defending Super Bowl champions, but they have had a rocky start to the season. Their defense still looks like one of the best defenses in the NFL, but the offense has some big issues that need to be fixed. They lost their OC to the Raiders, so this offense has looked different this season, but letting Kenneth Walker walk in the off-season was also a bad idea. They are coming off a 17-14 loss to the Broncos in their last one and they have to play another good defense here. The Chiefs have been rolling in their games this season as they are one of the few undefeated teams left in the NFL and acquiring Kenneth Walker has been a big part of that. He has helped transform this Chiefs offense this season, playing like one of the best RB's in the league, and he is going to bring his best effort against the team that let him walk after winning the Super Bowl. The Chiefs are coming off a 22-6 win over the Chargers in their last one and their offense has been rolling all season, putting up a ton of points in every game. The Chiefs have the talent to go toe-to-toe here with the defending champs and Walker will be a big reason why the Chiefs come away with the win. The best way to place a bet here is on the Chiefs to cover the spread in this game.
Chiefs Seahawks Prediction: Our NFL Pick for Sunday, October 25, 2026 (8:20 pm ET start time) is Chiefs 23 Seahawks 20.
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NFL Betting Trends
Kansas City Chiefs: 6-11 ATS in road games. 4-9 ATS after playing a division game. 0-3 ATS vs. good passing defenses - allowing 5.7 or less passing yards/att. 22-16 OVER against NFC West division opponents. 25-18 OVER versus good defensive teams - allowing 4.75 yards/play or less.
Seattle Seahawks: 20-12 ATS off an upset loss as a road favorite. 64-37 ATS after 2 or more consecutive losses. 67-50 ATS versus good rushing teams - averaging 4.5 rushing yards/carry or more. 18-10 OVER against AFC West division opponents. 47-23 OVER vs. good defensive teams who give up 17 or less points/game.
Key Injuries
Kansas City Chiefs: C. Allen (WR) Injured - Knee. C. Conner (CB) Injured - Knee. T. Kelce (TE) Injured - Ankle. P. Mahomes (QB) Injured - Knee. C. McDonald (LB) Injured - Knee. J. Moore (OG) Injured - Concussion. R. Rice (WR) Injured - Hamstring. T. Smith (OG) Injured - Hip. L. Sneed (CB) Injured - Knee.
Seattle Seahawks: U. Nwosu (LB) Injured - Hip. D. Lawrence (LB) Injured - Rest. D. Lock (QB) Injured - Elbow. C. Surratt (LB) Injured - Calf. R. Shaheed (WR) Injured - Hip. A. Bradford (OG) Injured - Knee. Z. Charbonnet (RB) Injured - Knee. D. Thomas (LB) Injured - Ankle. T. Knight (LB) Injured - Oblique. C. O'Toole (LB) Injured - Hamstring. B. Stephens (OG) Injured - Knee.
Notable Quotes
“It's great to win in this league. And it's hard. It's a hard thing to do. They're not always going to be pretty, but you have to battle through.” - Andy Reid after his team’s win against the LA Chargers in their last game.
“No moral victories in the league. It’s a bottom-line business, production business. But I’m proud of our effort. I’m proud of the resolve of the team. I’m proud of our connectedness of our team.” - Mike Macdonald after his team’s loss against the Broncos in their last game.
Starting Lineups
Kansas City Chiefs
WR Royals, Jalen
WR Worthy, Xavier
WR Allen, Cyrus
TE Kelce, Travis
QB Mahomes, Patrick
RB Walker, Kenneth
FB VanSumeren, Ben
Seattle Seahawks
WR Smith-Njigba, Jaxon
WR Shaheed, Rashid
WR Kupp, Cooper
TE Barner, AJ
QB Darnold, Sam
RB Charbonnet, Zach
FB Russell, Brady
Statistical Leaders
Kansas City Chiefs
Passing: Patrick Mahomes (1,309)
Rushing: Kenneth Walker III (665)
Receiving: Travis Kelce (299)
Touchdowns: Kenneth Walker III (8)
Seattle Seahawks
Passing: Sam Darnold (1,033)
Rushing: Emanuel Wilson (303)
Receiving: Jaxon Smith-Njigba (717)
Touchdowns: Jaxon Smith-Njigba (7)
Coaches:
Kansas City Chiefs: Andy Reid (14th season)
Seattle Seahawks: Mike Macdonald (3rd season)
Rod Pearson
About the Author:
Rod Pearson has been a rabid sports fan his entire life. He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years. In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective. Join Rod every day as he breaks down the games to find the best betting value.
