Jacksonville Jaguars vs Tennessee Titans Prediction, Preview and Odds - 11/30/2025

Game Time: 1:00 pm ET, Sunday, November 30, 2025

Venue:  Nissan Stadium, Nashville, TN

Where to Watch:  CBS

DraftKings:  Point Spread:  Jaguars -6.5, Titans +6.5; Over/Under:  42.5 points

Bet365:  Point Spread:  Jaguars -6.5, Titans +6.5; Over/Under:  41.5 points

BetMGM:  Point Spread:  Jaguars -6.5, Titans +6.5; Over/Under:  42 points

Jacksonville Jaguars:  7-4 (2nd place, AFC South)

Tennessee Titans:  1-10 (4th place, AFC South)

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Jacksonville Jaguars:  won their last game on the road against the Arizona Cardinals 27-24 in overtime.

Tennessee Titans:  lost their last game at home against the Seattle Seahawks 30-24.

The Jaguars are entering this game with a 7-4 record overall and they have a 1-1 record in their divisional games too. They are 4-1 in their home games, 3-2 in their road games, and they are also 0-1 in their neutral site games this season, but they will be on the road for this game. They won their last game against the Arizona Cardinals 27-24 in OT. Trevor Lawrence was the starting QB and he completed 18/30 passes for 256 passing yards, 3 touchdowns, and 3 interceptions. Travis Etienne Jr. led the team in rushing yards with 86. Brenton Strange led the receivers with 93 receiving yards on 5 receptions. Andrew Wingard led the defense in that game with 8 solo tackles and 2 assisted tackles while Dennis Gardeck and Devin Lloyd each led the defense in sacks with 1.5. No one on the defense came away with an interception for them in that one.

 

 

 

The Titans are entering this game with a 1-10 record overall and they have a 0-4 record in their divisional games too. They are 0-6 in their home games, 1-4 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They lost their last game against the Seattle Seahawks 30-24. Cameron Ward was the starting QB and he completed 28/42 passes for 256 passing yards, 1 touchdown, and 0 interceptions. Cameron Ward led the team in rushing yards with 37 and 1 TD. Gunnar Helm led the receivers with 51 receiving yards on 6 receptions. Kevin Winston Jr. led the defense in that game with 6 solo tackles and 4 assisted tackles while Arden Key led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.

The current betting odds have the Jaguars listed as a 6.5 point favorite in this game according to Draftkings Sportsbook. The Jaguars have looked good in their games this season with their 7-4 record overall which has them right near the top of the AFC South. They have been a good road team too with their 3-2 road record this season. Meanwhile, the Titans have looked terrible in their games this season with their 1-10 record overall which has them right at the bottom of the AFC South with the worst record in the entire NFL. They have looked terrible on their home field too with their 0-6 home record this season. They are off a 30-24 loss to the Seahawks in their last one and they were able to make that a close game in the end, but they were down big right from the start and they haven't really been in a lot of their games this season either. Their offense has looked terrible as Cam Ward is still struggling in his rookie season, and the defense can only do so much to keep them in their games. The Jaguars are off a 27-24 win over the Cardinals in their last one and it wasn't pretty, but they got the job done. They do have some impressive wins this season too. The Jaguars are going to be motivated after seeing the Colts drop a game at the top of the division so look for them to roll over one of the worst teams in the NFL who is just going through the motions this year. The best way to place a bet here is on the Jaguars to cover the spread in this game. 

Jaguars Titans Prediction:  Our NFL Pick for Sunday, November 30, 2025 (1:00 pm ET start time) is Jaguars 23 Titans 10.

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Jacksonville Jaguars: 9-4 ATS versus division opponents. 6-1 ATS vs. bad defensive teams who give up 24 or more points/game. 5-1 ATS vs. poor teams - outscored by 6+ points per game on the season. 8-2 OVER as a favorite of 3.5 to 9.5 points. 9-3 OVER in a road game where the total is between 42.5 and 49 points.

Tennessee Titans: 14-30 ATS in all games. 6-17 ATS as an underdog of 3.5 to 9.5 points. 3-13 ATS versus division opponents. 10-5 OVER as a home underdog. 8-1 OVER when playing against a good team (Win Pct. 60% to 75%).

Jacksonville Jaguars:  A. Armstead (DL) Injured - Hand. J. Lewis (CB) Injured - Neck. E. Murray (S) Injured - Neck. H. Long (TE) Injured - Knee. C. Edoga (OG) Injured - Calf. C. Braswell (CB) Injured - Hamstring. P. Mekari (OG) Injured - Concussion. Y. Abdullah (LB) Injured - Finger. T. Walker (DL) Injured - Knee. A. Johnson (S) Injured - Elbow. A. Harrison (OG) Injured - Knee. J. Jones (CB) Injured - Quad. B. Thomas Jr. (WR) Injured - Ankle. D. Striggow (DL) Injured - Knee.

Tennessee Titans:  K. Zeitler (OG) Injured - NIR - Rest. X. Woods (S) Injured - Hamstring. J. Ward (LB) Injured - NIR - Rest. S. Joseph-Day (DL) Injured - Elbow. L. Cushenberry III (C) Injured - Foot. T. Pollard (RB) Injured - NIR - Rest. J. Simmons (DL) Injured - NIR - Rest. D. Moore Jr. (OT) Injured - Knee. S. Tuttle (DL) Injured - Concussion. J. Armour-Davis (CB) Injured - Achilles. C. Okonkwo (TE) Injured - Foot. K. Brooks (CB) Injured - Concussion. E. Ayomanor (WR) Injured - Hamstring.

“Guys stepped up, nobody flinched, nobody was walking around with their head down and frustrated. You've got to keep playing. That's been the message for the last few weeks. And these guys closed it out when we needed it.” - Liam Coen after his team’s win against the Cardinals in their last game. 

“We’ve each got to be more consistent because these guys fought their tails off once again up until the very end. But got to be more consistent throughout a game.” - Mike McCoy after his team’s loss against the Seahawks in their last game. 

WR Patrick, Tim

WR Meyers, Jakobi

WR Washington, Parker

TE Strange, Brenton

QB Lawrence, Trevor 

RB Etienne Jr., Travis

WR Kinsey, Mason

WR Jefferson, Van

WR Dike, Chimere

TE Okonkwo, Chig

QB Ward, Cam

RB Pollard, Tony

Passing: Trevor Lawrence (2,407)

Rushing: Travis Etienne Jr. (815)

Receiving: Parker Washington (421)

Touchdowns: Travis Etienne Jr. (7)

Passing: Cam Ward (2,210)

Rushing: Tony Pollard (522)

Receiving: Chig Okonkwo (377)

Touchdowns: Elic Ayomanor (2)

Coaches:

Jacksonville Jaguars: Liam Coen (1st season)

Tennessee Titans: Mike McCoy (Interim)