Jacksonville Jaguars vs Indianapolis Colts Prediction, Preview and Odds - 09/10/2023

Game Time: 1:00 pm ET, Sunday, September 10, 2023

Venue:  Lucas Oil Stadium, Indianapolis, IN

Where to Watch:  FOX

DraftKings:  Point Spread:  Jaguars -5, Colts +5; Over/Under:  45 points

Bet365:  Point Spread:  Jaguars -4.5, Colts +4.5; Over/Under:  45 points

BetMGM:  Point Spread:  Jaguars -4.5, Colts +4.5; Over/Under:  45 points

Jacksonville Jaguars:  0-0 (AFC South)

Indianapolis Colts:  0-0 (AFC South)

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Jacksonville Jaguars:  N/A

Indianapolis Colts:  N/A

The Jaguars finished last season with a 9-8 record overall and they were 4-2 in their division games too. They had a 5-3 record in their home games and had a 4-5 record in their road games where they will be in this game. Last season, their offense was averaging 23.8 points per game and their defense was allowing an average of 20.6 points per game. Their offense was also averaging 357.4 yards per game and their defense was allowing an average of 353.3 yards per game. Trevor Lawrence led the team in passing yards with 4113, Travis Etienne led the team in rushing yards with 1125, and Christian Kirk led the team in receiving yards with 1108.

The Colts finished last season with a 4-12-1 record overall and they were 1-4-1 in their division games too. They had a 2-6 record in their home games and had a 2-6-1 record in their road games where they will be in this game. Last season, their offense was averaging 17 points per game and their defense was allowing an average of 25.1 points per game. Their offense was also averaging 311.6 yards per game and their defense was allowing an average of 334 yards per game. Matt Ryan led the team in passing yards with 3057, Jonathan Taylor led the team in rushing yards with 861, and Michael Pittman Jr. led the team in receiving yards with 925.

The current betting odds have the Jaguars listed as a 5 point favorite in this game according to Draftkings Sportsbook. The Jaguars had a much improved season last year with their 9-8 record overall winning the AFC Title too, but they fizzled out in the playoffs and they will be looking to take a big step this season in Lawrence's 3rd season in the NFL and Pederson's 2nd season as head coach. Doug Pederson really turned this team around last season and now they have surrounded Lawrence with a lot of talent on this offense, both in the running game and the receiving game. Meanwhile, the Colts were terrible last season with their 4-12-1 record overall and they have hired a new head coach for this season now. Steichen is in his 1st season as head coach with a rookie QB Anthony Richardson who they drafted but this offense is still lacking a lot of talent, especially with the running game since Taylor is still dealing with injuries and disgruntled with the team. The Colts may be at home for this 1st game of the season but Steichen is not going to have everyone on the same page here in his 1st year as coach with a rookie QB and not a whole lot of talent around. This Jaguars team is looking to be the next dominant force in the AFC South though and they will be looking to have an even better season this year which all starts with a big win in this division game. The best way to place a bet here is on the Jaguars to cover the spread in this game. 

Jaguars Colts Prediction:  Our NFL Pick for Sunday, September 10, 2023 (1:00 pm ET start time) is Jaguars 28 Colts 13.

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Jacksonville Jaguars: 1-6 ATS as a favorite. 1-5 ATS in a road game where the total is between 42.5 and 45 points. 4-11 ATS in the first half of the season. 22-14 UNDER in all games. 16-9 UNDER in all games where the total is between 42.5 and 49 points. 

Indianapolis Colts: 8-4 ATS as an underdog of 3.5 to 9.5 points. 18-7 ATS as a home underdog of 3.5 to 7 points. 15-8 UNDER as a home underdog of 3.5 to 7 points. 8-2 UNDER in a home game where the total is between 42.5 and 49 points. 

Jacksonville Jaguars:  J. Wells (OT) I-R - Groin. D. Smoot (DE) Out indefinitely - Achilles. V. Miller (LB) I-R - Achilles. D. Hamilton (DT) Out indefinitely - Back. L. Taylor (TE) I-R - Undisclosed. C. Claybrooks (CB) Ques Week 1 - Poss. Suspension. C. Robinson (OL) Elig Week 5 - Suspension.

Indianapolis Colts:  J. Woods (TE) Ques Week 1 - Hamstring. R. Seals-Jones (TE) I-R - Foot. J. Domann (LB) I-R - Shin. D. Pinter (G) I-R - Ankle. T. Leo (DE) I-R - Undisclosed. J. Taylor (RB) Out indefinitely - Ankle. G. Avery (DE) I-R - Knee. A. Dulin (WR) I-R - Knee. Z. Moss (RB) Ques Week 1 - Arm. J. Witt (OT) I-R - Hip. C. Lammons (DB) Elig Week 4 - Suspension. D. Scott (S) I-R - Knee.

“I just want to give a quick update on DaVon, which I know you’re going to ask. He’s doing extremely well. Obviously, it’s a non-football-related injury. He’s doing extremely well, and our doctor said that he could be back in our building as early as next week, so we’re happy for that." - Doug Pederson on the injury to DaVon Hamilton. 

"Yeah, he's been doing a tremendous job so far, and we gotta keep that going through the season. It's a gauntlet season, 17 weeks, new opponent every week. new game plan every week, and we've gotta be ready to roll." - Shane Steichen on Anthony Richardson coming into this new NFL season.

WR Ridley, Calvin 

WR Jones, Zay 

WR Kirk, Christian 

TE Engram, Evan 

QB Lawrence, Trevor 

RB Etienne Jr., Travis 

WR Pittman Jr., Michael 

WR Pierce, Alec 

WR McKenzie, Isaiah 

TE Alie-Cox, Mo 

QB Richardson, Anthony 

RB Moss, Zack 

Passing: N/A

Rushing: N/A

Receiving: N/A

Touchdowns: N/A

Passing: N/A

Rushing: N/A

Receiving: N/A

Touchdowns: N/A

Coaches:

Jacksonville Jaguars: Doug Pederson (2nd season)

Indianapolis Colts: Shane Steichen (1st season)