Iowa Hawkeyes vs Iowa State Cyclones Prediction, Picks and Game Preview - 12/11/2025

Game Time: 8:00 pm ET, Thursday, December 11, 2025

Venue:  Hilton Coliseum, Ames, IA 

Where to Watch:  Fox Sports 1

DraftKings:  Point Spread:  Iowa +11.5, ISU -11.5; Over/Under:  145.5 points

Bet365:  Point Spread:  Iowa +11.5, ISU -11.5; Over/Under:  145.5 points

BetMGM:  Point Spread:  Iowa +11.5, ISU -11.5; Over/Under:  145.5 points

Iowa Hawkeyes:  8-1 (1-1) (10th place, Big Ten)

Iowa State Cyclones:  9-0 (0-0) (1st place, Big 12)

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Iowa Hawkeyes:  4-1  last 5

Iowa State Cyclones:  5-0  last 5

Iowa is entering this game with an 8-1 record overall, a 1-1 record in conference games, and they are 0-1 in their road games this season where they will be in this game. They are coming off a win against the Maryland Terrapins in their last game. Bennett Stirtz led the team in points in that game with 25 while Cam Manyawu and Tate Sage each was next on the team with 12. Cam Manyawu, Tavion Banks, and Tate Sage each led the team in assists with 3 in that game while Cam Manyawu and Tavion Banks each led the team in rebounds with 7. They were 54% from the field, 40.9% from 3-point range, and 50% from the free throw line with their shooting in that game. Their offense is averaging 79.9 PPG and their defense is allowing their opponents to average 62.6 PPG against them. Iowa has an ATS record of 7-2 this season and their O/U record is 5-4.

Iowa State is entering this game with a 9-0 record overall, a 0-0 conference record, and they are 4-0 in their home games this season where they will be in this game. They are coming off a win against the Purdue Boilermakers in their last game. Milan Momcilovic led the team in points in that game with 20 while Killyan Toure was next on the team with 13. Tamin Lipsey led the team in assists with 8 in that game while Blake Buchanan led the team in rebounds with 9. They were 54.1% from the field, 47.8% from 3-point range, and 66.7% from the free throw line with their shooting in that game. Their offense is averaging 94.6 PPG and their defense is allowing their opponents to average 64.6 PPG against them. Iowa State has an ATS record of 7-1-1 this season and their O/U record is 6-3.

The current betting odds have Iowa State listed as an 11.5 point favorite in this game according to Draftkings Sportsbook. Iowa State has looked great in their games this season with their 9-0 record overall which has them right at the top of the Big 12. They have looked great on their home court too with their 4-0 home record this season, and they are ranked inside the top 5 teams in the nation at the moment. Meanwhile, Iowa has looked really good in their games this season with their 8-1 record overall, but their 1-1 conference record has them lower in the Big Ten. They haven't been a good road team either with their 0-1 road record this year, losing the only road game they have played in the conference to Michigan State. They are off a home win over Maryland in their last one, but they weren't really competitive in that loss to Michigan State and MSU is one of the strongest teams in the Big Ten this year. Iowa State has been rolling in their games this season, picking up some impressive wins against ranked opponents, and they are off a road win over Purdue in their last one. Purdue is not only one of the best teams in the Big Ten, but they are one of the best teams in the nation and Iowa State completely embarrassed them on their own court. Iowa doesn't have the talent to go toe-to-toe with Iowa State here, especially on the road. The best way to place a bet here is on Iowa State to cover the spread in this game. 

Iowa Iowa State Prediction:  Our NCAAB Pick for Thursday, December 11, 2025 (8:00 pm ET start time) is Iowa State 88 Iowa 72.

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Iowa Hawkeyes: 9-22 ATS as an underdog. 8-16 ATS in road games. 3-8 ATS versus up-tempo teams averaging 62 or more shots/game. 11-21 ATS versus very good teams - outscoring their opponents by 8+ points/game. 14-6 OVER after a win by 15 points or more. 4-1 OVER against Big 12 conference opponents.

Iowa State Cyclones: 52-26 ATS in all games. 25-11 ATS as a home favorite or pick. 25-12 ATS after a win by 15 points or more. 27-14 ATS versus very good teams - outscoring their opponents by 8+ points/game. 25-12 OVER after a win by 15 points or more. 

Iowa Hawkeyes:  T. Thompson (F) Questionable - Undisclosed.

Iowa State Cyclones:  M. Williams (G) Out - Hip.

“People undervalue the ability to screen, and the angles. That’s something that is probably, if it’s not the most important thing for our offense, it’s pretty close. The variety of screening angles and the variety of ways we come out at screens, how we set those things up, is probably just as important.” - Ben McCollum on his team this season.

“I think we're always looking at ways to make our program better and the way we do things better and evaluating even from year to year what things [we] felt went well or we could be better. It's always an evolution.” - T.J. Otzelberger on the upcoming Cy-Hawk battle.

T. Banks 

K. Combs 

C. Koch 

C. Manyawu 

B. Stirtz

B. Buchanan 

J. Jefferson 

T. Lipsey 

M. Momcilovic 

K. Toure

PPG: Bennett Stirtz (18.8)

APG: Bennett Stirtz (4.9)

Reb/G: Cam Manyawu (4.3)

PPG: Milan Momcilovic (18.3)

APG: Tamin Lipsey (5.7)

Reb/G: Joshua Jefferson (6.7)

Coaches:

Iowa Hawkeyes: Ben McCollum (1st season)

Iowa State Cyclones: T.J. Otzelberger (5th season)