Indianapolis Colts vs Jacksonville Jaguars Prediction, Preview and Odds - 11/01/2026

Game Time: 1:00 pm ET, Sunday, November 1, 2026

Venue:  EverBank Stadium, Jacksonville, FL

Where to Watch:  CBS

DraftKings:  Point Spread:  Colts +7.5, Jaguars -7.5; Over/Under:  46.5 points

Bet365:  Point Spread:  Colts +7.5, Jaguars -7.5; Over/Under:  46.5 points

BetMGM:  Point Spread:  Colts +7.5, Jaguars -7.5; Over/Under:  46.5 points

Indianapolis Colts:  2-5 (2nd place, AFC South)

Jacksonville Jaguars:  4-2 (1st place, AFC South)

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Indianapolis Colts:  lost their last game on the road against the Minnesota Vikings 16-10.

Jacksonville Jaguars:  lost their last game at a neutral site against the Houston Texans 34-31.

The Colts are entering this game with a 2-5 record overall and they have a 1-1 record in their divisional games too. They are 1-2 in their home games, 0-3 in their road games, and they are also 1-0 in their neutral site games this season, but they will be on the road for this game. They lost their last game against the Minnesota Vikings 16-10. Daniel Jones was the starting QB and he completed 13/22 passes for 108 passing yards, 0 touchdowns, and 1 interception. Jonathan Taylor led the team in rushing yards with 95 and 1 TD. Keenan Allen led the receivers with 31 receiving yards on 3 receptions. A.J. Haulcy led the defense in that game with 9 solo tackles while Adetomiwa Adebawore led the defense in sacks with 2. No one on the defense came away with an interception for them in that one.

 

 

 

The Jaguars are entering this game with a 4-2 record overall and they have a 0-1 record in their divisional games too. They are 2-0 in their home games, 1-1 in their road games, and they are also 1-1 in their neutral site games this season, but they will be at home for this game. They lost their last game against the Houston Texans 34-31. Trevor Lawrence was the starting QB and he completed 24/41 passes for 306 passing yards, 4 touchdowns, and 1 interception. Chris Rodriguez Jr. led the team in rushing yards with 55. Jakobi Meyers led the receivers with 83 receiving yards on 5 receptions. Foyesade Oluokun led the defense in that game with 8 solo tackles while no one on the defense recorded a sack for them. Travis Hunter came away with the only interception for them in that one.

The current betting odds have the Jaguars listed as a 7.5 point favorite in this game according to Draftkings Sportsbook. The Jaguars have looked good in their games this season with their 4-2 record overall which has them right at the top of the AFC South. They have looked great on their home field too with their 2-0 home record this season. Meanwhile, the Colts haven't looked good in their games this season with their 2-5 record overall, but that record has them right near the top of the AFC South. They have been a terrible road team though with their 0-3 road record this year. The Colts are coming off a 16-10 loss to the Vikings in their last one and they put up a good fight against a really good defense, but their offense couldn't get anything going. They have been dealing with some injuries on offense, but their defense has also been really bad this season. The Jaguars are coming off a 34-31 loss to the Texans in their last one which was in London, but the Jags will be looking to bounce back now that they are back at home. They spent 2 weeks in London, but they did take their bye week right after, so they have 2 weeks to prepare for this game and they have a big opportunity to spread the gap in this division. They have a really good defense that has been great in both of their home games this season, not giving up many points in either game, and their offense has been rolling this year with half of their games seeing them put up over 30 points. Both of their home wins this season have been blow out wins too and this game will be no different with how bad the Colts have looked lately. The best way to place a bet here is on the Jaguars to cover the spread in this game. 

Colts Jaguars Prediction:  Our NFL Pick for Sunday, November 1, 2026 (1:00 pm ET start time) is Jaguars 35 Colts 20.

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Indianapolis Colts: 1-5 ATS vs. good passing teams averaging 7 or more passing yards/att. 3-6 ATS when playing against a good team (Win Pct. 60% to 75%). 3-8 ATS vs. good offensive teams - scoring 24 or more points/game. 18-10 OVER against conference opponents. 7-2 OVER vs. poor passing defenses - allowing 7 or more passing yards/att.

Jacksonville Jaguars: 12-5 ATS in home games. 9-2 ATS in a home game where the total is between 42.5 and 49 points. 8-1 ATS vs. bad defensive teams who give up 24 or more points/game. 8-2 OVER after playing a division game. 9-4 OVER when playing against a team with a losing record.

Indianapolis Colts:  None.

Jacksonville Jaguars:  None.

“I've got a ton of faith in Daniel.” - Shane Steichen after his team’s loss against the Vikings in their last game. 

“We didn’t get the result we wanted. (But) I’m extremely proud of this team in the way they kept fighting today, going down 10 points ... kept fighting.” - Liam Coen after his team’s loss against the Texans in their last game. 

WR Treadwell, Laquon

WR Allen, Keenan

WR Downs, Josh

TE Alie-Cox, Mo

QB Jones, Daniel

RB Taylor, Jonathan

WR Cameron, Josh

WR Meyers, Jakobi

WR Washington, Parker

TE Strange, Brenton

QB Lawrence, Trevor

RB Tuten, Bhayshul 

Passing: Daniel Jones (1,398)

Rushing: Jonathan Taylor (587)

Receiving: Josh Downs (307)

Touchdowns: Jonathan Taylor (8)

Passing: Trevor Lawrence (1,480)

Rushing: Bhayshul Tuten (388)

Receiving: Parker Washington (416)

Touchdowns: Parker Washington (4)

Coaches:

Indianapolis Colts: Shane Steichen (4th season)

Jacksonville Jaguars: Liam Coen (2nd season)