Indiana Hoosiers vs Purdue Boilermakers Prediction, Picks and Game Preview - 02/20/2026

Game Time: 8:00 pm ET, Friday, February 20, 2026

Venue:  Mackey Arena, West Lafayette, IN

Where to Watch:  FOX

DraftKings:  Point Spread:  Indiana +10.5, Purdue -10.5; Over/Under:  148.5 points

Bet365:  Point Spread:  Indiana +10.5, Purdue -10.5; Over/Under:  148.5 points

BetMGM:  Point Spread:  Indiana +10.5, Purdue -10.5; Over/Under:  148.5 points

Indiana Hoosiers:  17-9 (8-7) (10th place, Big Ten)

Purdue Boilermakers:  21-5 (11-4) (3rd place, Big Ten)

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Indiana Hoosiers:  3-2  last 5

Purdue Boilermakers:  4-1  last 5

Indiana is entering this game with a 17-9 record overall, an 8-7 record in conference games, and they are 3-6 in their road games this season where they will be in this game. They are coming off a loss against the Illinois Fighting Illini in their last game. Lamar Wilkerson led the team in points in that game with 21 while Tucker DeVries was next on the team with 13. Conor Enright led the team in assists with 6 in that game while Sam Alexis led the team in rebounds with 8. They were 40.8% from the field, 25% from 3-point range, and 83.3% from the free throw line with their shooting in that game. Their offense is averaging 80.3 PPG and their defense is allowing their opponents to average 71.3 PPG against them. Indiana has an ATS record of 13-13 this season and their O/U record is 12-14.

Purdue is entering this game with a 21-5 record overall, an 11-4 conference record, and they are 11-3 in their home games this season where they will be in this game. They are coming off a loss against the Michigan Wolverines in their last game. Trey Kaufman-Renn led the team in points in that game with 27 while Braden Smith was next on the team with 20. Braden Smith led the team in assists with 6 in that game while Trey Kaufman-Renn led the team in rebounds with 12. They were 39.1% from the field, 30.8% from 3-point range, and 90% from the free throw line with their shooting in that game. Their offense is averaging 82.5 PPG and their defense is allowing their opponents to average 69.5 PPG against them. Purdue has an ATS record of 12-14 this season and their O/U record is 12-14.

The current betting odds have Purdue listed as a 10.5 point favorite in this game according to Draftkings Sportsbook. Purdue has looked great in their games this season with their 21-5 record overall and their 11-4 conference record which has them right near the top of the Big Ten. They have looked great on their home court too with their 11-3 home record this season. Meanwhile, Indiana has looked good in their games this season with their 17-9 record overall and their 8-7 conference record which has them right in the middle of the Big Ten. They haven't been a good road team though with their 3-6 road record this year. Indiana has been really up and down this season and they haven't looked bad lately, going 3-2 in their last 5 games, but they are off a loss to Illinois in their last one and have struggled a lot against top opponents this year. They did pick up a win at home over Purdue earlier this season, but that is only going to make the target on their back bigger here. Purdue has had their own trouble in the conference this season, but their trouble has mainly been against top teams in the Big Ten. They have been beating up on weaker teams all year and they are going to be coming for some revenge in this one too. Purdue has looked a lot better lately as they are 4-1 in their last 5 games, but they are off a home loss to Michigan in their last one and they will be looking to bounce back here. That wasn't a great loss for them since they are trying to be the best in the Big Ten and that game showed where they stand, but Michigan is also pulling away from the rest of the Big Ten as they look like one of the best in the nation. Look for Purdue to bounce back big in this rivalry game and take out their frustrations against an inferior opponent. The best way to place a bet here is on Purdue to cover the spread in this game. 

Indiana Purdue Prediction:  Our NCAAB Pick for Friday, February 20, 2026 (8:00 pm ET start time) is Purdue 87 Indiana 67.

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Indiana Hoosiers: 1-4 ATS off a road loss. 2-6 ATS after playing a road game. 3-6 ATS versus good rebounding teams - outrebounding opponents by 4+ per game. 6-3 UNDER in road games. 5-1 UNDER off a loss against a conference rival.

Purdue Boilermakers: 26-17 ATS when playing against a good team (Win Pct. 60% to 80%). 31-22 ATS versus very good teams - outscoring their opponents by 8+ points/game. 6-3 ATS when the total is 140 to 149.5. 8-2 1H UNDER after allowing 85 points or more.

Indiana Hoosiers:  J. Drake (G) Questionable - Undisclosed. J. Rayford (G) Out - Undisclosed. J. Harris (F) Questionable - Undisclosed.

Purdue Boilermakers:  None.

“I think there's probably a few components. No. 1, just the communication aspect of play calls and that type of stuff, being able to relay that stuff. Then anytime you get some environment, having your team be able to stay composed during those stretches and stuff. So that's what makes all the sports, home courts, so advantageous, is having that type of environment behind you.” - Darian DeVries on playing at Mackey Arena.

“Our goal was to win the Big Ten. But those dudes aren’t losing four (conference) games. We’ve got four losses, and they ain’t losing four games, that’s just reality. When you’ve been in the league for 25 years, that’s reality.” - Matt Painter after his team’s loss against Michigan in their last game. 

S. Alexis 

T. Conerway 

T. DeVries 

C. Enright 

L. Wilkerson

O. Cluff 

C. Cox 

T. Kaufman-Renn 

F. Loyer 

B. Smith

PPG: Lamar Wilkerson (21.2)

APG: Conor Enright (4.8)

Reb/G: Tucker DeVries (5.3)

PPG: Braden Smith (14.9)

APG: Braden Smith (8.8)

Reb/G: Trey Kaufman-Renn (9.1)

Coaches:

Indiana Hoosiers: Darian DeVries (1st season)

Purdue Boilermakers: Matt Painter (21st season)