Indiana Hoosiers vs Maryland Terrapins Prediction, Picks and Game Preview - 11/01/2025

by Rod Pearson

Wednesday, Oct 29, 2025
Game Time: 3:30 pm ET, Saturday, November 1, 2025
Venue:  SECU Stadium, College Park, MD
Where to Watch:  CBS


Opening Odds at USA Sportsbooks

DraftKings:  Point Spread:  Indiana -21.5, Maryland +21.5; Over/Under:  50.5 points
Bet365:  Point Spread:  Indiana -21.5, Maryland +21.5; Over/Under:  50.5 points
BetMGM:  Point Spread:  Indiana -21.5, Maryland +21.5; Over/Under:  50.5 points

Season Record

Indiana Hoosiers:  8-0 (5-0) (1st place, Big Ten)
Maryland Terrapins:  4-3 (1-3) (13th place, Big Ten)

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Recent Form
Indiana Hoosiers:  won their last game at home against the UCLA Bruins 56-6.
Maryland Terrapins:  lost their last game on the road against the UCLA Bruins 20-17.


Indiana Hoosiers vs Maryland Terrapins Preview and Analysis


Indiana is entering this game with an 8-0 record overall and they have a 5-0 record in their conference games too. They are 6-0 in their home games, 2-0 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against UCLA 56-6. Fernando Mendoza was the starting QB and he completed 15/22 passes for 168 passing yards, 3 touchdowns, and 1 interception. Roman Hemby led the team in rushing yards with 81 and 2 TDs. E.J. Williams Jr. led the receivers with 109 receiving yards on 5 receptions and 1 TD. Isiah Jones led the defense in that game with 4 solo tackles and 4 assisted tackles while Tyrique Tucker led the defense in sacks with 1.5. Devan Boykin and Aiden Fisher came away with 1 interception for them in that one.
 
 
 
Maryland is entering this game with a 4-3 record overall and they have a 1-3 record in their conference games too. They are 3-2 in their home games, 1-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They lost their last game against UCLA 20-17. Malik Washington was the starting QB and he completed 23/48 passes for 210 passing yards, 1 touchdown, and 1 interception. Malik Washington led the team in rushing yards with 67. DeJuan Williams led the receivers with 86 receiving yards on 7 receptions. Daniel Wingate led the defense in that game with 8 solo tackles and 1 assisted tackle while Sidney Stewart led the defense in sacks with 1. Jamare Glasker and Jalen Huskey each came away with 1 interception for them in that one.


Indiana vs Maryland Prediction

The current betting odds have Indiana listed as a 21.5 point favorite in this game according to Draftkings Sportsbook. Indiana has looked great in their games this season with their 8-0 record overall and their 5-0 conference record which has them right at the top of the Big Ten. They are ranked inside the top 3 in the nation and they have been rolling over the teams they have played all year. They are off a 56-6 win over a hot UCLA team in their last one and they also have a really impressive road win over Oregon too. Meanwhile, Maryland has looked good in their games this season with their 4-3 record overall, but their 1-3 conference record has them right near the bottom of the Big Ten. They are coming out of their bye week and have had extra time to prepare for this game, but they don't have the talent that Indiana has. They are off a road loss to UCLA in their last one, losing 20-17, and they have blown some leads late this season too. Their offense hasn't looked great either as they don't put up a ton of points in their games and they are going to struggle just to move the ball against this Indiana defense. Indiana has established themselves as one of the best teams in the nation this season and they are going to continue rolling in this game like they have been doing lately. The best way to place a bet here is on Indiana to cover the spread in this game. 

Indiana Maryland Prediction:  Our NCAAF Pick for Saturday, November 1, 2025 (3:30 pm ET start time) is Indiana 49 Maryland 10.
Don't miss our champion handicappers free picks and expert football picks today. And if you enjoyed this Indiana Hoosiers Maryland Terrapins prediction, be sure to drop by every day for our weekly NCAAF predictions and previews.

NCAAF Betting Trends


Indiana Hoosiers: 21-12 ATS in all lined games. 14-7 ATS as a favorite. 8-2 ATS off a home win by 17 points or more. 11-3 ATS after allowing 14 points or less last game. 22-11 OVER in all lined games. 9-3 OVER in road lined games. 15-4 OVER after playing a game at home.

Maryland Terrapins: 3-6 ATS in a home game where the total is between 49.5 and 56. 1-4 ATS off a road loss against a conference rival. 1-4 ATS off a road loss. 12-6 OVER in home lined games. 6-1 OVER against teams with a turnover margin of +1 per game or better. 

Key Injuries


Indiana Hoosiers:  K. Wyatt (DL) Questionable - Undisclosed. B. Bonds (CB) Out - Undisclosed. L. Beebe Jr. (RB) Out - Leg. T. Morris (WR) Out - Knee.

Maryland Terrapins:  Z. Mathis (DL) Questionable - Undisclosed. L. Haughton Jr. (TE) Questionable - Undisclosed. J. Martin (QB) Questionable - Undisclosed. L. Irvin III (CB) Questionable - Undisclosed. J. McLaurin (RB) Questionable - Undisclosed. J. Gilchrist (OG) Questionable - Undisclosed. S. Foye (RB) Out - Undisclosed. D. Samuels (LB) Out - Undisclosed. M. McMonigle (OG) Out - Undisclosed. B. Coombs (RB) Out - Undisclosed. J. Jenkins (CB) Out - Undisclosed. K. James (LB) Out - Undisclosed.

Notable Quotes


“It was on a big platform against a team that was hot, and we wanted to be physical and dominate the line of scrimmage, and I thought we did that early in the game. Fisher made a huge play early in the game.” - Curt Cignetti after his team’s win against UCLA in their last game. 


“We've lost three Big Ten games by a combined 10 points in the last three weeks. I'm not going to ask what is the issue, or why this keeps happening. Why is a victim question, and I'm not a victim. I'm going to ask what we need to do or what I need to do to be able to get us to finish these games.” - Mike Locksley after his team’s loss against UCLA in their last game. 


Starting Lineups


Indiana Hoosiers
WR Sarratt, Elijah
WR Williams Jr., E.J.
WR Cooper Jr., Omar
TE Nowakowski, Riley
QB Mendoza, Fernando
RB Hemby, Roman

Maryland Terrapins
WR Smith Jr., Octavian
WR Knotts, Shaleak
WR Farooq, Jalil
TE Fleming, Dorian
QB Washington, Malik
RB Ray, Nolan

Statistical Leaders


Indiana Hoosiers
Passing: Fernando Mendoza (1,923)
Rushing: Roman Hemby (513)
Receiving: Elijah Sarratt (609)
Touchdowns: Elijah Sarratt (10)

Maryland Terrapins
Passing: Malik Washington (1,716)
Rushing: DeJuan Williams (292)
Receiving: Shaleak Knotts (421)
Touchdowns: Shaleak Knotts (5)

Coaches:
Indiana Hoosiers: Curt Cignetti (2nd season)
Maryland Terrapins: Mike Locksley (8th season)


Rod Pearson

About the Author:

Rod Pearson has been a rabid sports fan his entire life.  He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years.  In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective.  Join Rod every day as he breaks down the games to find the best betting value.

All photographic images used for editorial content have been licensed from the Associated Press.

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