by Rod Pearson
Friday, Nov 14, 2025
Game Time: 1:00 pm ET, Sunday, November 16, 2025
Venue: Nissan Stadium, Nashville, TN
Where to Watch: FOX
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: Texans -5.5, Titans +5.5; Over/Under: 37.5 points
Bet365: Point Spread: Texans -6, Titans +6; Over/Under: 37 points
BetMGM: Point Spread: Texans -6, Titans +6; Over/Under: 37 points
Season Record
Houston Texans: 4-5 (3rd place, AFC South)
Tennessee Titans: 1-8 (4th place, AFC South)
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Recent Form
Houston Texans: won their last game at home against the Jacksonville Jaguars 36-29.
Tennessee Titans: lost their last game at home against the Los Angeles Chargers 27-20.
Houston Texans vs Tennessee Titans Preview and Analysis
The Texans are entering this game with a 4-5 record overall and they have a 2-1 record in their divisional games too. They are 3-2 in their home games, 1-3 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against the Jacksonville Jaguars 36-29. Davis Mills was the starting QB and he completed 27/45 passes for 292 passing yards, 2 touchdowns, and 1 interception. Jo'quavious Marks led the team in rushing yards with 63 and 1 TD. Nico Collins led the receivers with 136 receiving yards on 7 receptions. Danielle Hunter led the defense in that game with 5 solo tackles and 2 assisted tackles while Danielle Hunter led the defense in sacks with 3.5. Derek Stingley Jr. came away with the only interception for them in that one.
The Titans are entering this game with a 1-8 record overall and they have a 0-3 record in their divisional games too. They are 0-4 in their home games, 1-4 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They lost their last game against the Los Angeles Chargers 27-20. Cameron Ward was the starting QB and he completed 12/21 passes for 145 passing yards, 0 touchdowns, and 0 interceptions. Tony Pollard led the team in rushing yards with 56. Elic Ayomanor led the receivers with 46 receiving yards on 3 receptions. Cedric Gray led the defense in that game with 11 solo tackles and 5 assisted tackles while Jihad Ward led the defense in sacks with 2.5. Cody Barton came away with the only interception for them in that one.
Texans vs Titans Prediction
The current betting odds have the Texans listed as a 5.5 point favorite in this game according to Draftkings Sportsbook. The Texans haven't looked good in their games this season with their 4-5 record overall which has them right near the bottom of the AFC South. They were missing their starting QB Stroud in their last one and could be without him again, but they did find a way to get the win without him. Meanwhile, the Titans have looked terrible in their games this season with their 1-8 record overall which has them right at the bottom of the AFC South with the worst record in the entire NFL. They are coming out of their bye week after losing to the Chargers 27-20 in their last one, but that was one of the better games they have played all season. They have been getting blown out in a lot of their games as Cam Ward is still trying to figure things out in his rookie season, and he doesn't have a lot of talent around him on the offense either. The Texans offense has been terrible this season, even when Stroud has been playing, but they do have one of the best defenses in the NFL. This isn't going to be an easy game for Cam Ward against one of the best defenses in the NFL, and Davis Mills did find a spark in this offense last week in their 36-29 win over the Jags. This is a must win game for the Texans to get back into the division race and their offense will be able to do enough here while the defense does the rest. The best way to place a bet here is on the Texans to cover the spread in this game.
Texans Titans Prediction: Our NFL Pick for Sunday, November 16, 2025 (1:00 pm ET start time) is Texans 17 Titans 6.
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NFL Betting Trends
Houston Texans: 7-1 ATS in a road game where the total is between 35.5 and 42 points. 10-2 ATS after playing a division game. 9-3 ATS versus poor defensive teams - allowing 350 yards/game or more. 27-17 UNDER in all games. 9-5 UNDER after playing a division game.
Tennessee Titans: 12-30 ATS in all games. 5-17 ATS as an underdog of 3.5 to 9.5 points. 2-13 ATS versus division opponents. 9-3 UNDER when playing against a team with a losing record.
Key Injuries
Houston Texans: K. Fairbairn (K) Injured - Right Quad. D. Autry (DL) Injured - Knee. B. Berrios (WR) Injured - Quad. D. Schultz (TE) Injured - Shoulder. A. Al-Shaair (LB) Injured - Knee. H. Bryant (TE) Injured - Neck. J. Pitre (S) Injured - Concussion. J. Hansen (LB) Injured - Elbow. E. Ingram (OG) Injured - Knee. D. Mills (QB) Injured - Left Elbow. J. Johnson (FB) Injured - Elbow. T. Howard (OT) Injured - Concussion. C. Harris (LB) Injured - Shin. C. Stroud (QB) Injured - Concussion. C. Stover (TE) Injured - Foot.
Tennessee Titans: L. Cushenberry III (C) Injured - Ankle. K. Zeitler (OG) Injured - Rest. X. Woods (S) Injured - Hamstring. C. Ridley (WR) Injured - Hamstring. A. Key (LB) Injured - Quadricep. J. Lynch (DL) Injured - Shoulder. J. Simmons (DL) Injured - Hamstring. M. Brown (S) Injured - Knee. C. Okonkwo (TE) Injured - Foot. B. Oliver (WR) Injured - Knee. C. Ravenell (DL) Injured - Ankle. K. Mullings (RB) Injured - Ankle.
Notable Quotes
“The key for our entire game was, no one blinked. I told the guys last night it was going to be a heavyweight fight. I wanted us to continue forward, keep punching.” - DeMeco Ryans after his team’s win against the Jaguars in their last game.
“The big turning point obviously is getting stopped on the 1-yard line, then a big drive go down there and score so that's the difference. It’s frustrating to look at it because of the missed opportunities that we had early.” - Mike McCoy after his team’s loss against the LA Chargers in their last game.
Starting Lineups
Houston Texans
WR Collins, Nico
WR Hutchinson, Xavier
WR Kirk, Christian
TE Schultz, Dalton
QB Mills, Davis
RB Marks, Woody
FB Brooks, British
Tennessee Titans
WR Ayomanor, Elic
WR Jefferson, Van
WR Dike, Chimere
TE Okonkwo, Chig
QB Ward, Cam
RB Pollard, Tony
Statistical Leaders
Houston Texans
Passing: C.J. Stroud (1,702)
Rushing: Nick Chubb (402)
Receiving: Nico Collins (550)
Touchdowns: Woody Marks (4)
Tennessee Titans
Passing: Cam Ward (1,760)
Rushing: Tony Pollard (480)
Receiving: Elic Ayomanor (323)
Touchdowns: Elic Ayomanor (2)
Coaches:
Houston Texans: DeMeco Ryans (3rd season)
Tennessee Titans: Mike McCoy (Interim)
Rod Pearson
About the Author:
Rod Pearson has been a rabid sports fan his entire life. He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years. In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective. Join Rod every day as he breaks down the games to find the best betting value.
