by Rod Pearson
Tuesday, Dec 23, 2025
Game Time: 4:30 pm ET, Saturday, December 27, 2025
Venue: SoFi Stadium, Inglewood, CA
Where to Watch: NFL Network
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: Texans +2.5, Chargers -2.5; Over/Under: 39.5 points
Bet365: Point Spread: Texans +2, Chargers -2; Over/Under: 39.5 points
BetMGM: Point Spread: Texans +2, Chargers -2; Over/Under: 39.5 points
Season Record
Houston Texans: 10-5 (2nd place, AFC South)
Los Angeles Chargers: 11-4 (2nd place, AFC West)
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Recent Form
Houston Texans: won their last game at home against the Las Vegas Raiders 23-21.
Los Angeles Chargers: won their last game on the road against the Dallas Cowboys 34-17.
Houston Texans vs Los Angeles Chargers Preview and Analysis
The Texans are entering this game with a 10-5 record overall and they have a 4-1 record in their divisional games too. They are 6-2 in their home games, 4-3 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against the Las Vegas Raiders 23-21. C. J. Stroud was the starting QB and he completed 23/35 passes for 187 passing yards, 1 touchdown, and 0 interceptions. Jawhar Jordan led the team in rushing yards with 53. Nico Collins led the receivers with 59 receiving yards on 4 receptions. Jalen Pitre led the defense in that game with 6 solo tackles and 1 assisted tackle while Will Anderson Jr., Derek Barnett, and Danielle Hunter each led the defense in sacks with 1. Derek Stingley Jr. came away with the only interception for them in that one.
The Chargers are entering this game with an 11-4 record overall and they have a 5-0 record in their divisional games too. They are 5-2 in their home games, 5-2 in their road games, and they are also 1-0 in their neutral site games this season, but they will be at home for this game. They won their last game against the Dallas Cowboys 34-17. Justin Herbert was the starting QB and he completed 23/29 passes for 300 passing yards, 2 touchdowns, and 0 interceptions. Omarion Hampton led the team in rushing yards with 85 and 1 TD. Quentin Johnston led the receivers with 104 receiving yards on 4 receptions and 1 TD. Derwin James Jr. led the defense in that game with 5 solo tackles and 1 assisted tackle while Tuli Tuipulotu led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.
Texans vs Chargers Prediction
The current betting odds have the Texans listed as a 2.5 point underdog in this game according to Draftkings Sportsbook. The Texans have looked really good in their games this season with their 10-5 record overall which has them right near the top of the AFC South. They have been a good road team too with their 4-3 road record this year. Meanwhile, the Chargers have looked really good in their games this season with their 11-4 record overall which has them right near the top of the AFC West. They have also looked great on their home field this year with their 5-2 home record. The Chargers have been rolling in their games lately as they continue to find ways to win games with all of their injuries. They have a ton of momentum on their side with 4 wins in a row now and they are off a 34-17 win over the Cowboys in their last one. The Texans have also been rolling in their games lately though, winning 7 games in a row now, and they are off a 23-21 win over the Raiders in their last one. Both of these teams are sitting in 2nd place in their respective divisions and both still have a chance to win their divisions, but the Texans are in a better situation here. The Chargers have looked a lot better on defense lately, but the Texans have one of the best defenses in the NFL that hasn't been giving up many points all year, and they are going to be all over this banged up Chargers offense. The Chargers have also been getting by a lot with Herbert carrying the team on his back, but even he is banged up with a hand injury and will struggle against this Texans defense. The Texans haven't had a great offense this year, but their offense has been starting to click lately and that makes them a very dangerous team. The best way to place a bet here is on the Texans to cover the spread in this game.
Texans Chargers Prediction: Our NFL Pick for Saturday, December 27, 2025 (4:30 pm ET start time) is Texans 17 Chargers 14.
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NFL Betting Trends
Houston Texans: 8-2 ATS in a road game where the total is between 35.5 and 42 points. 4-1 ATS after a 2 game home stand. 11-5 ATS when playing against a good team (Win Pct. 60% to 75%). 10-5 UNDER as a road underdog. 13-7 UNDER when playing against a team with a winning record.
Los Angeles Chargers: 1-5 ATS against AFC South division opponents. 24-35 ATS vs. good passing defenses - allowing 5.7 or less passing yards/att. 38-22 UNDER vs. good passing defenses - allowing 5.7 or less passing yards/att. 33-20 UNDER at home vs. good teams - outscoring opponents by 6+ PPG on the season.
Key Injuries
Houston Texans: None.
Los Angeles Chargers: None.
Notable Quotes
“It doesn’t matter how it looks, it’s beautiful to get the win. I’m proud of our team for continuing to find ways to win.” - DeMeco Ryans after his team’s win against the Raiders in their last game.
“We got the ball out quick, had a great protection plan and really were on our stuff this week. So it’s a shoutout to the front five for just communicating, talking and blocking as well as they did.” - Justin Herbert after their win against the Cowboys in their last game.
Starting Lineups
Houston Texans
WR Collins, Nico
WR Higgins, Jayden
WR Kirk, Christian
TE Schultz, Dalton
QB Stroud, C.J.
RB Chubb, Nick
FB Brooks, British
Los Angeles Chargers
WR Johnston, Quentin
WR Allen, Keenan
WR McConkey, Ladd
TE Gadsden, Oronde
QB Herbert, Justin
RB Hampton, Omarion
FB Matlock, Scott
Statistical Leaders
Houston Texans
Passing: C.J. Stroud (2,628)
Rushing: Woody Marks (584)
Receiving: Nico Collins (1,060)
Touchdowns: Nico Collins (7)
Los Angeles Chargers
Passing: Justin Herbert (3,491)
Rushing: Kimani Vidal (631)
Receiving: Ladd McConkey (758)
Touchdowns: Quentin Johnston (8)
Coaches:
Houston Texans: DeMeco Ryans (3rd season)
Los Angeles Chargers: Jim Harbaugh (2nd season)
Rod Pearson
About the Author:
Rod Pearson has been a rabid sports fan his entire life. He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years. In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective. Join Rod every day as he breaks down the games to find the best betting value.
