Houston Rockets vs Philadelphia 76ers Prediction, Preview and Odds - 01/22/2026

Game Time: 7:00 pm ET, Thursday, January 22, 2026

Venue:  Xfinity Mobile Arena, Philadelphia, PA

Where to Watch:  SCHN, NBCS-P

DraftKings:  Point Spread:  Rockets -2.5, 76ers +2.5; Over/Under:  221.5 points

Bet365:  Point Spread:  Rockets -2.5, 76ers +2.5; Over/Under:  221.5 points

BetMGM:  Point Spread:  Rockets -2.5, 76ers +2.5; Over/Under:  221.5 points

Houston Rockets:  26-15 (2nd place, Southwest Division)

Philadelphia 76ers:  23-19 (4th place, Atlantic Division)

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Houston Rockets:  5-5 last 10

Philadelphia 76ers:  5-5 last 10

The Rockets are entering this game with a 26-15 record overall this season and they are 11-12 in their road games this season where they will be in this game. They are entering this game on a 3 game winning streak with wins coming against the Minnesota Timberwolves, the New Orleans Pelicans, and the San Antonio Spurs. Reed Sheppard led the team in points in that game with 21 while Alperen Şengün was next on the team with 20 points. Alperen Şengün led the team in assists in that game with 9 while Alperen Şengün led the team in rebounds with 13. They were 51.8% from the field, 37% from 3-point range, and 68.2% from the free throw line with their shots in that game. Their offense is averaging 117 PPG and their defense is allowing their opponents to average 110.5 PPG against them. The Rockets have an ATS record of 20-21 this season and their O/U record is 19-21-1.

The 76ers are entering this game with a 23-19 record overall this season and they are 11-12 in their home games this season where they will be in this game. They are entering this game off a loss against the Phoenix Suns. V. J. Edgecombe led the team in points in that game with 25 while Kelly Oubre Jr. was next on the team with 21 points. Tyrese Maxey led the team in assists in that game with 7 while Andre Drummond led the team in rebounds with 15. They were 41.9% from the field, 32.4% from 3-point range, and 77.8% from the free throw line with their shots in that game. Their offense is averaging 116.5 PPG and their defense is allowing their opponents to average 115.4 PPG against them. The 76ers have an ATS record of 24-18 this season and their O/U record is 22-20.

The current betting odds have the Rockets listed as a 2.5 point favorite in this game according to Draftkings Sportsbook. The Rockets have looked good in their games this season with their 26-15 record overall which has them in the top half of the West. They haven't been a good road team though with their 11-12 road record this year. Meanwhile, the 76ers have looked good in their games this season with their 23-19 record overall which has them in the top half of the East. They haven't looked great on their home court though with their 11-12 home record this season. The 76ers haven't looked that great lately either, going 5-5 in their last 10 games and coming off a home loss to the Suns in their last one. They have been struggling a lot more in their home games this season and they have also been dealing with injuries throughout the year as both Embiid and George have been in and out of the lineup. The Rockets have been a more steady team this season though and they look like a team that can be one of the best in the West this year. They are only 5-5 in their last 10 games too, but they have looked better lately with 3 wins in a row now and will come into this one with some momentum on their side. They are off a win over the Spurs in their last one and have been rolling lately with some good wins against top teams in the West. The Rockets are starting to get into a groove now and they can take advantage of the 76ers with their home troubles this year. The best way to place a bet here is on the Rockets to cover the spread in this game. 

Rockets 76ers Prediction:  Our NBA Pick for Thursday, January 22, 2026 (7:00 pm ET start time) is Rockets 112  76ers 106.

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Houston Rockets: 10-6 ATS off a home win against a division rival. 19-11 ATS after playing 3 consecutive home games. 18-12 OVER after playing 3 consecutive home games. 27-19 OVER when playing 8 or more games in 14 days.

Philadelphia 76ers: 29-37 ATS in non-conference games. 9-15 ATS after playing 3 consecutive home games. 16-7 OVER against Southwest division opponents. 20-13 OVER when playing against a good team (Win Pct. 60% to 70%).

Houston Rockets:  S. Adams (C) Out - Ankle. F. VanVleet (PG) Out For Season - ACL.

Philadelphia 76ers:  J. Embiid (C) Day To Day - Injury Management. P. George (PF) Day To Day - Knee.

“We had good energy the whole game. When we cut the lead a little bit there in the fourth quarter, it was just ‘keep fighting, keep staying together, we’re close, keep putting the pieces together and go on a big run’. And that’s what we did. It was a great team effort.” - Reed Sheppard after their win against the Spurs in their game on Tuesday.

"I think, obviously they used a bunch of guys on him. They were super physical on him. I did think he got some pretty decent opportunities. Just, unfortunately, he had a little bit of a cold shooting night, but he also, I thought they were physical, and did a lot of switching, used a bunch of different guys on him, full court, pressure, all that kind of stuff." - Nick Nurse after his team’s loss against the Suns in their game on Tuesday.

PG Amen Thompson

SG Kevin Durant

SF Tari Eason

PF Jabari Smith Jr.

C Alperen Sengun

PG Tyrese Maxey

SG VJ Edgecombe

SF Paul George

PF Dominick Barlow

C Joel Embiid

PPG: Kevin Durant (25.9)

APG: Alperen Sengun (6.4)

Reb/G: Alperen Sengun (9.3)

PPG: Tyrese Maxey (30)

APG: Tyrese Maxey (6.7)

Reb/G: Andre Drummond (9)

Coaches:

Houston Rockets: Ime Udoka (3rd season)

Philadelphia 76ers: Nick Nurse (3rd season)