Houston Astros vs. Baltimore Orioles: Prediction, Preview, Picks & Odds - 9/23/2022

by Chuck Sommers

Time: 7:05 p.m. ET
Venue: Oriole Park at Camden Yards, Baltimore, MD
Where to watch: AT&T SportsNet-Southwest, MASN

Opening Odds at USA Sportsbooks

DraftKings: Astros -145, Orioles +125
FanDuel: Astros -154, Orioles +130
BetMGM: Astros -154, Orioles +125
Caesars: Astros -155, Orioles +130

Season record
Astros: 99-52
Orioles: 78-71

We're coming down to the wire in the MLB season. Playoff races are heating up, pennant races are still to be decided, and MVP cases are still to be made. Are you in the right headspace to finish strong entering the postseason? Look no further than what Al McMordie has done as of late, going 53-37 in his last 90 in MLB plays! You know you want that type of winning in your life. Make sure you check out Al's and our other champion handicappers to see who they have down the stretch this season

Astros - Orioles preview and analysis

With 13 games remaining, the Baltimore Orioles have life. It’s absurd to think the Orioles can still make the playoffs. It would take a Herculean effort for Baltimore to make the most absurd of leaps to make the playoffs, sitting four games back of the Seattle Mariners for the final wild card spot, and even 4.5 back of the Tampa Bay Rays. There’s still life, but the young O’s are running out of time.

But Baltimore got off to a great start with its backs against the wall with a 2-0 win over the Houston Astros on Thursday to take the first game of the series, which continues in Baltimore on Friday fresh off an impressive win over Justin Verlander.

It was a night for Trey Mancini’s return to Baltimore after being an original hero from that group. But it was a night that belonged to Baltimore. All it took was two runs in the second inning, a two-run single from Rougned Odor. Kyle Bradish nearly went the distance at 8.2 innings and striking out 10 to defeat the best team in the American League.

Bradish took a perfect game into the sixth but still stayed in to deliver one hell of a performance.

"I knew if a runner gets on, I was going to come out. It's a two-run ballgame, and Bautista was fresh, and we've got to win these games," Bradish said. "I wasn't too happy that I didn't finish it, but I completely understand."

"Just feeling good," he said. "Routine was good today, arm felt really good. Pregame bullpen, really good. Everything was working."

The Orioles’ season has been nothing but spectacular. That franchise has been longing for something to cheer for over the course of 10 years. Ever since the Manny Machado era came to an end, they haven’t had much to get excited about. They’ve gone straight to the youth movement and it has been an incredible moment. If they can get some more wins and inch closer to the wild card race.

But it’s almost a shame that the Orioles are fighting for their lives, knock off Verlander and the Astros in a 2-0 win and still have to find themselves climbing up the proverbial tree in order to keep their race alive. Verlander went only six innings, but he’s looking to make a late push for the AL Cy Young case despite dealing with a calf injury throughout August.

“He has a lot at stake,” Astros manager Dusty Baker said. “He’s trying to win 20 [games]. Trying to win the ERA title. He’s in a position to win the Cy. We’re pulling for him. When you’re in that position, you want to go take it.”

Perhaps it was the emotional moment of Mancini coming back and going 0 for 3, but there’s no reason why the Astros shouldn’t bounce back in this one.

“When I got traded, I put out in my statement that my relationship with the city transcends baseball and it always will,” Mancini said.


Jose Urquidy takes the mound as a 13-game winner on Friday, facing Dean Kremer who has been very good for the Orioles. I can’t imagine the Astros losing another game when things are starting to go haywire. Astros win 4-3

Betting trends

Astros are 22-7 as a road favorite between -125 and -175 this year.

Astros are 13-12 against AL East teams this season.

Orioles are 32-25 when they're an underdog between +125 and +175.

Orioles are 19-10 agianst AL West opponents this year.

Projected lineup

Jeremy Pena (R) SS
Aledmys Diaz (R) 2B
Yordan Alvarez (L) LF
Alex Bregman (R) 3B
Kyle Tucker (L) RF
Trey Mancini (R) 1B
Christian Vazquez (R) C
Yainer Diaz (R) DH
Mauricio Dubon (R) CF

Cedric Mullins (L) CF
Adley Rutschman (S) C
Gunnar Henderson (L) 3B
Anthony Santander (S) DH
Ryan Mountcastle (R) 1B
Terrin Vavra (L) LF
Kyle Stowers (L) RF
Rougned Odor (L) 2B
Jorge Mateo (R) SS

Statistical leaders

Batting average: Yordan Alvarez -- .300
Home runs: Yordan Alvarez -- 37
RBI: Kyle Tucker -- 102
Wins: Justin Verlander -- 17
ERA: Justin Verlander -- 1.82

Batting average: Cedric Mullins -- .262
Home runs: Anthony Santander -- 27
RBI: Ryan Mountacastle -- 80
Wins: Jordan Lyles -- 11
ERA: Jordan Lyles -- 4.50

Don't miss our champion handicappers' free picks and expert MLB picks today. And if you enjoyed this Houston Astros - Baltimore Orioles preview, be sure to drop by every day for our daily MLB projections and predictions.

Chuck Sommers

About the Author:

Chuck Sommers has camped outside of sportsbooks since he can remember, learning the tricks and nuances of the trade. He still has nightmares of betting $5,000 on the Raiders in the Tuck Rule game but has since turned that to 25 years of veteran handicapping greatness. You can find him mostly in the shadows at the Red Rock or Aliante casinos wondering if the over is cashing on any given Sunday.

All photographic images used for editorial content have been licensed from the Associated Press.

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