Houston Astros vs Baltimore Orioles Prediction, Preview and Odds - 09/25/2022

by Rod Pearson

Game Time: 1:05 pm ET, Sunday, September 25, 2022
Venue:  Oriole Park at Camden Yards, Baltimore, MD
Where to Watch:  MASN

 

Opening Odds at USA Sportsbooks

DraftKings:  Moneyline odds:  Astros -150, Orioles +130; Over/Under:  7.5 runs
Bet365:  Moneyline odds:  Astros -150, Orioles +130; Over/Under:  7.5 runs
BetMGM:  Moneyline odds:  Astros -150, Orioles +130; Over/Under:  7.5 runs
 

Season Record

Houston Astros:  99-53 (1st place, AL West)
Baltimore Orioles:  79-71 (4th place, AL East)
 
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Recent Form
Houston Astros:  7-3 last 10
Baltimore Orioles:  6-4 last 10
 
 
 

Houston Astros vs Baltimore Orioles Preview and Analysis

 
The Astros enter this game on a 2 game losing streak. They won their last series against the Tampa Bay Rays 3-0 completing the sweep in a 3-game series. They enter this game with a 99-53 record overall and have a road record of 49-30. This is the series finale of a 4-game series with the Orioles on Sunday with the 3rd game still to be played on Saturday. Their offense ranks 7th in the MLB with a .740 OPS. Framber Valdez is their starting pitcher on Saturday while Cristian Javier is making his start in this game on Sunday. He is 10-9 with a 2.77 ERA this season. His team won their last 4 straight games this season with him making an appearance. In his last start, he allowed 0 ER, 0 HRs, and 4 BB with 6 Ks on 1 hit through 5 IP against the Tampa Bay Rays.
 
The Orioles enter this game on a 3 game winning streak. They lost their last series against the Detroit Tigers 2-1 in a 3-game series. They enter this game with a 79-71 record overall and have a home record of 44-32. This is the 4th game of a 4-game series with the Astros on Sunday with the 3rd game still to be played on Saturday. Their offense ranks 22nd in the MLB with a .691 OPS. Mike Baumann is their starting pitcher on Saturday while Austin Voth is making his start in this game on Sunday. He is 5-3 with a 4.32 ERA this season. His team won 3 of their last 4 games this season with him making an appearance. In his last start, he allowed 2 earned runs, 1 homer, and 0 BB with 3 strikeouts on 6 hits through 5 innings played against the Detroit Tigers.

 

Astros vs Orioles Prediction

The current betting odds have the Astros listed as a favorite in this game according to Draftkings Sportsbook. The Astros have been great over the last week, they haven't won a game in this series yet but they are not going to come away from this empty handed. They have already lost 2 games which means they cannot win this series but they can still split it and they will be focused on getting the wins in these last 2 games. The Orioles have been good in these 2 games as they haven't given up a run against the Astros in 2 games but that is not going to stay like that for long and their bats will wake up here. The Orioles don't have a very reliable starter here and the Astros have one of their best going in Valdez. Valdez just had a great outing in his last start and he has been pitching that way all year. He won't give up many runs to the Orioles here and the Astros should be able to win this game with great pitching, but their bats will also wake up against Baumann. The best way to place a bet here is on the Astros to win this game.
 
Astros Orioles Prediction:  Our MLB Pick for Sunday, September 25, 2022 (1:05 pm ET start time) is Astros 5 Orioles 1.
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MLB Betting Trends

 
Houston Astros: 13-14 (-4.6 Units) ML against AL East opponents. 88-54 UNDER in all games. 46-26 UNDER in road games.
Baltimore Orioles: 79-71 (+31.6 Units) ML in all games. 44-32 (+17.3 Units) ML in home games. 31-22 UNDER as an underdog of +125 to +175.
 

Key Injuries

 
Houston Astros:  J. James (RP) out for season - Back. M. Brantley (LF) out for season - Shoulder. J. Castro (C) out for season - Knee.
Baltimore Orioles:  R. Urias (SS) Ques Sat - Neck. T. Wells (RP) out for season - Shoulder. C. Ellis (SP) out for season - Shoulder. J. Means (SP) out for season - Elbow.
 
 

Notable Quotes

 
"They pitched great against us. We don't like it. We're not happy about it, but sometimes things don't go your way. They've pretty much taken it to us the past couple of days." - Dusty Baker after his team’s loss against the Orioles on Friday.
 
 
"It's contagious. Maybe Bradish saw what Jordan did, and Dean saw what Bradish and Jordan did and just wanted to keep it going." - Brandon Hyde after his team’s win against the Astros in their game on Friday.
 
 

Starting Lineups

 
Houston Astros
Jose Altuve (R) 2B
Jeremy Pena (R) SS
Yordan Alvarez (L) LF
Alex Bregman (R) 3B
Yuli Gurriel (R) 1B
Aledmys Diaz (R) DH
Trey Mancini (R) RF
Chas McCormick (R) CF
Martin Maldonado (R) C
 
Baltimore Orioles
Cedric Mullins (L) CF
Adley Rutschman (S) C
Ryan Mountcastle (R) 1B
Anthony Santander (S) RF
Gunnar Henderson (L) 3B
Jesus Aguilar (R) DH
Austin Hays (R) LF
Terrin Vavra (L) 2B
Jorge Mateo (R) SS
 

Statistical Leaders

 
Houston Astros
Batting Average:  Yordan Alvarez (.301)
Hits:  Jose Altuve (148)
Home Runs:  Yordan Alvarez (37)
RBI:  Kyle Tucker (102)
Stolen Bases:  Kyle Tucker (22)
Wins:  Justin Verlander (17)
Saves:  Ryan Pressly (30)
ERA:  Ryne Stanek (1.05)
 
Baltimore Orioles
Batting Average:  Gunnar Henderson (.296)
Hits:  Cedric Mullins (148)
Home Runs:  Anthony Santander (27)
RBI:  Anthony Santander (81)
Stolen Bases:  Jorge Mateo (33)
Wins:  Jordan Lyles (11)
Saves:  Felix Bautista (15)
ERA:  Cionel Perez (1.36)
 
Managers:
Houston Astros: Dusty Baker (3rd season)
Baltimore Orioles: Brandon Hyde (4th season)


Rod Pearson

About the Author:

Rod Pearson has been a rabid sports fan his entire life.  He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years.  In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective.  Join Rod every day as he breaks down the games to find the best betting value.

All photographic images used for editorial content have been licensed from the Associated Press.

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