Green Bay Packers vs Detroit Lions Prediction, Preview and Odds - 10/25/2026

Game Time: 4:25 pm ET, Sunday, October 25, 2026

Venue:  Ford Field, Detroit, MI 

Where to Watch:  FOX

DraftKings:  Point Spread:  Packers +3, Lions -3; Over/Under:  53.5 points

Bet365:  Point Spread:  Packers +3, Lions -3; Over/Under:  53.5 points

BetMGM:  Point Spread:  Packers +3, Lions -3; Over/Under:  53.5 points

Green Bay Packers:  4-2 (3rd place, NFC North)

Detroit Lions:  3-2 (4th place, NFC North)

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Green Bay Packers:  won their last game at home against the Dallas Cowboys 23-13.

Detroit Lions:  won their last game on the road against the Arizona Cardinals 45-21.

The Packers are entering this game with a 4-2 record overall and they have a 1-1 record in their divisional games too. They are 2-1 in their home games, 2-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against the Dallas Cowboys 23-13. Jordan Love was the starting QB and he completed 23/41 passes for 276 passing yards, 1 touchdown, and 1 interception. Pierre Strong Jr. led the team in rushing yards with 28. Matthew Golden led the receivers with 104 receiving yards on 6 receptions and 1 TD. Keisean Nixon led the defense in that game with 8 solo tackles while Lukas Van Ness led the defense in sacks with 1. Evan Williams and Brandon Cisse each came away with 1 interception for them in that one.

 

 

 

The Lions are entering this game with a 3-2 record overall and they have a 0-0 record in their divisional games too. They are 2-0 in their home games, 1-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against the Arizona Cardinals 45-21. Jared Goff was the starting QB and he completed 19/30 passes for 271 passing yards, 3 touchdowns, and 0 interceptions. Jahmyr Gibbs led the team in rushing yards with 151 and 2 TDs. Sam LaPorta led the receivers with 88 receiving yards on 5 receptions and 1 TD. Jack Campbell led the defense in that game with 11 solo tackles while D.J. Wonnum led the defense in sacks with 2. Keith Abney II came away with the only interception for them in that one.

The current betting odds have the Lions listed as a 3 point favorite in this game according to Draftkings Sportsbook. The Lions have looked good in their games this season with their 3-2 record overall, but that record has them right at the bottom of the NFC North in a really competitive division. They have looked great on their home field though with their 2-0 home record this season. Meanwhile, the Packers have looked good in their games this season with their 4-2 record overall which has them right in the middle of the NFC North. They have been a good road team too with their 2-1 road record this year. The Packers have been up and down this season with some major issues on offense, but lately they have looked a lot better. They are coming off a 23-13 win over the Cowboys in their last one and their defense has looked great, but they aren't a team that is putting up a ton of points from game to game. They should be getting Jacobs back here which is big for their offense, but they haven't had a good rushing attack all season and a lot of that is due to the injuries on their offensive line. The Lions are in a much better situation here and they have been getting healthier lately with some key players on defense coming back for this game. They won their last game against the Cardinals 45-21, but they are also coming out of their bye week and they have had extra time to prepare for the Packers. The Lions are undefeated at home this season and have looked great at home under Campbell over the last few years, so that home advantage is going to play a big factor in this game. The Lions are also going to have extra motivation here since they lost both games to the Packers last season, so look for the Lions to come out of their bye week strong and make a statement as a contender in the NFC North. The best way to place a bet here is on the Lions to cover the spread in this game. 

Packers Lions Prediction:  Our NFL Pick for Sunday, October 25, 2026 (4:25 pm ET start time) is Lions 31 Packers 24.

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Green Bay Packers: 6-12 ATS in road games. 2-8 ATS vs. poor passing defenses - allowing 235 or more passing yards/game. 1-4 ATS vs. bad defensive teams who give up 24 or more points/game. 7-2 OVER vs. poor passing defenses - allowing 235 or more passing yards/game. 8-3 OVER versus poor defensive teams - allowing 350 yards/game or more. 

Detroit Lions: 11-6 ATS after playing their last game on the road. 4-1 ATS after a 2 game road trip. 6-3 ATS vs. good passing teams averaging 235 or more passing yards/game. 14-5 OVER in a home game where the total is greater than or equal to 45.5. 15-6 OVER after scoring 30 points or more last game.

Green Bay Packers:  Z. Franklin (LB) Injured - Shin. L. Van Ness (DL) Injured - Illness. J. Riley (DL) Injured - Achilles. B. St-Juste (CB) Injured - Hamstring. C. Watson (WR) Injured - Ankle. S. Williams (WR) Injured - Ankle. A. Banks (OG) Injured - Knee. A. Campbell (DL) Injured - Ankle. B. Cisse (CB) Injured - Shoulder. M. Golden (WR) Injured - Shoulder. J. Love (QB) Injured - Back. B. Melton (WR) Injured - Back.

Detroit Lions:  R. Ya-Sin (CB) Injured - Hamstring. C. Mays (C) Injured - Wrist. B. Branch (CB) Injured - Achilles.

“I want to make every throw. I want these guys to make every catch. That’s the expectation. Stuff happens. Drops happen. Obviously, I want those guys to make those plays, and we’re capable of making those plays. But for me, it’s got to be the next play mindset. You’ve got to move on.” - Jordan Love after their win against the Cowboys in their last game. 

“The important thing is you go all in, no matter what you're going to do. And either it crumbles or they rise up, but you're going all in. You've got to push your chips all the way in and you've got to believe in it. So we did. We applied a little pressure and the players really responded.” - Dan Campbell after his team’s win against the Cardinals in their last game. 

WR Watson, Christian

WR Golden, Matthew

WR Williams, Savion

TE Kraft, Tucker

QB Love, Jordan

RB Jacobs, Josh

WR TeSlaa, Isaac

WR Williams, Jameson

WR St. Brown, Amon-Ra

TE LaPorta, Sam

QB Goff, Jared

RB Gibbs, Jahmyr

Passing: Jordan Love (1,684)

Rushing: MarShawn Lloyd (122)

Receiving: Christian Watson (538)

Touchdowns: Christian Watson (6)

Passing: Jared Goff (1,485)

Rushing: Jahmyr Gibbs (504)

Receiving: Amon-Ra St. Brown (372)

Touchdowns: Jahmyr Gibbs (9)

Coaches:

Green Bay Packers: Matt LaFleur (8th season)

Detroit Lions: Dan Campbell (6th season)