Florida Gators vs Duke Blue Devils Prediction, Picks and Game Preview - 12/02/2025

Game Time: 7:30 pm ET, Tuesday, December 2, 2025

Venue:  Cameron Indoor Stadium, Durham, NC

Where to Watch:  ESPN

DraftKings:  Point Spread:  Florida +9.5, Duke -9.5; Over/Under:  155.5 points

Bet365:  Point Spread:  Florida +9.5, Duke -9.5; Over/Under:  155.5 points

BetMGM:  Point Spread:  Florida +8.5, Duke -8.5; Over/Under:  156.5 points

Florida Gators:  5-2 (0-0) (11th place, SEC)

Duke Blue Devils:  8-0 (0-0) (1st place, ACC)

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Florida Gators:  4-1  last 5

Duke Blue Devils:  5-0  last 5

Florida is entering this game with a 5-2 record overall, a 0-0 record in conference games, and they are 0-0 in their road games this season where they will be in this game. They are coming off a win against the Providence Friars in their last game. Xaivian Lee led the team in points in that game with 20 while Urban Klavzar was next on the team with 18. Thomas Haugh led the team in assists with 5 in that game while Thomas Haugh led the team in rebounds with 12. They were 42.4% from the field, 36.4% from 3-point range, and 81.5% from the free throw line with their shooting in that game. Their offense is averaging 85.9 PPG and their defense is allowing their opponents to average 72.6 PPG against them. Florida has an ATS record of 1-6 this season and their O/U record is 2-5.

Duke is entering this game with an 8-0 record overall, a 0-0 conference record, and they are 4-0 in their home games this season where they will be in this game. They are coming off a win against the Arkansas Razorbacks in their last game. Cameron Boozer led the team in points in that game with 35 while Caleb Foster was next on the team with 15. Caleb Foster led the team in assists with 8 in that game while Cameron Boozer led the team in rebounds with 9. They were 49.2% from the field, 34.8% from 3-point range, and 66.7% from the free throw line with their shooting in that game. Their offense is averaging 91.9 PPG and their defense is allowing their opponents to average 58.8 PPG against them. Duke has an ATS record of 6-2 this season and their O/U record is 1-7.

The current betting odds have Duke listed as a 9.5 point favorite in this game according to Draftkings Sportsbook. Duke has looked great in their games this season with their 8-0 record overall which has them right at the top of the ACC and ranked like one of the best teams in the nation. They have also looked great on their home court this year with their 4-0 home record. Meanwhile, Florida hasn't looked great in their games this season with their 5-2 record overall which has them in the bottom half of the SEC. They are still ranked inside the top 25 teams in the nation and they have a lot of talent as the defending National Champions, but this is going to be their first true road game of the season. They have played in some neutral site games, but not in a hostile environment like this. They are also missing a key player in their lineup and they just haven't looked right in their games all season. Duke has been rolling over teams in their games though and most of their wins have been in games that weren't even close. They have some ranked wins under their belt too, coming off a 9 point win over Arkansas in their last one. Florida is going to struggle in this first road game of the season and Duke hasn't really shown any weaknesses with none of their games being close. Duke may be the higher ranked team here, but they are still going to bring their best effort for the team that won the National Championship last season. The best way to place a bet here is on Duke to cover the spread in this game. 

Florida Duke Prediction:  Our NCAAB Pick for Tuesday, December 2, 2025 (7:30 pm ET start time) is Duke 84 Florida 68.

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Florida Gators: 7-3 ATS against ACC opponents. 4-1 ATS after failing to cover the spread in 3 or more consecutive games. 26-12 ATS versus very good teams - outscoring their opponents by 8+ points/game. 25-14 OVER versus very good teams - outscoring their opponents by 8+ points/game.

Duke Blue Devils: 4-7 ATS after 3 or more consecutive unders. 4-9 1H ATS versus poor 3 point shooting teams - making 31% of their attempts or less. 6-11 1H ATS versus up-tempo teams averaging 62 or more shots/game. 5-1 OVER at home versus up-tempo teams averaging 62 or more shots/game. 

Florida Gators:  A. Condon (F-C) Questionable - Face.

Duke Blue Devils:  S. Wilkins (G-F) Out - Redshirt.

"We felt like we left one on the table yesterday and controlled the game up 10 in the second half with five or four minutes to go, whatever it was. Again, credit to TCU, I thought they made some plays, but we really felt like we missed a good opportunity yesterday.” - Todd Golden after his team’s win against Providence in their last game. 

"Nik is just a winner, man. He's a big-time competitor. I thought he had key rebounds, especially down the stretch in traffic. His ability to stay in front of guards — he guarded [Arkansas guard Meleek Thomas] a lot, he guarded [Darius Acuff Jr.] — he made life difficult [for the Razorbacks]. They hit a couple shots, and he's just a connecting, winning player on offense.” - Jon Scheyer on Nik Khamenia after his team’s win against Arkansas in their last game. 

R. Chinyelu 

A. Condon 

B. Fland 

T. Haugh 

X. Lee

C. Boozer 

I. Evans 

C. Foster 

P. Ngongba 

D. Sarr

PPG: Thomas Haugh (17.9)

APG: Xaivian Lee (4)

Reb/G: Rueben Chinyelu (10.9)

PPG: Cameron Boozer (22.9)

APG: Cameron Boozer (3.9)

Reb/G: Cameron Boozer (9.8)

Coaches:

Florida Gators: Todd Golden (4th season)

Duke Blue Devils: Jon Scheyer (4th season)