Duke Blue Devils vs Syracuse Orange Prediction, Picks and Game Preview - 02/05/2025

Game Time: 7:00 pm ET, Wednesday, February 5, 2025

Venue:  JMA Wireless Dome, Syracuse, NY 

Where to Watch:  ESPN2

DraftKings:  Point Spread:  Duke -18.5, Syracuse +18.5; Over/Under:  143 points

Bet365:  Point Spread:  Duke -18.5, Syracuse +18.5; Over/Under:  143 points

BetMGM:  Point Spread:  Duke -18.5, Syracuse +18.5; Over/Under:  143 points

Duke Blue Devils:  19-2 (11-0) (1st place, ACC)

Syracuse Orange:  10-12 (4-7) (14th place, ACC)

Do not miss out on our expert handicapper analysis! Big Al McMordie is on a HOT STREAK in college basketball on a 75-58 CBB RUN for +$11,300 PROFIT! Make sure you check out his picks and many more from the expert handicappers featured in the Shop Picks section.

Duke Blue Devils:  5-0  last 5

Syracuse Orange:  2-3  last 5

Duke is entering this game with a 19-2 record overall, an 11-0 record in conference games, and they are 6-0 in their road games this season where they will be in this game. They are coming off a win against the North Carolina Tar Heels in their last game. Kon Knueppel led the team in points per game in that game with 22 while Cooper Flagg was next on the team with 21. Cooper Flagg led the team in assists with 7 in that game while Cooper Flagg led the team in rebounds with 8. They were 52.8% from the field, 50% from 3-point range, and 84% from the free throw line with their shooting in that game. Their offense is averaging 80.3 PPG and their defense is allowing their opponents to average 60 PPG against them. Duke has an ATS record of 13-8 this season and their O/U record is 9-12.

Syracuse is entering this game with a 10-12 record overall, a 4-7 conference record, and they are 8-4 in their home games this season where they will be in this game. They are coming off a win against the California Golden Bears in their last game. Lucas Taylor led the team in points in that game with 19 while JJ Starling was next on the team with 18. JJ Starling led the team in assists with 4 in that game while Eddie Lampkin Jr. led the team in rebounds with 10. They were 46.3% from the field, 50% from 3-point range, and 85% from the free throw line with their shooting in that game. Their offense is averaging 74.2 PPG and their defense is allowing their opponents to average 77 PPG against them. Syracuse has an ATS record of 12-9-1 this season and their O/U record is 9-12-1.

The current betting odds have Duke listed as an 18.5 point favorite in this game according to Draftkings Sportsbook. Duke has looked really good in their games this season with their 19-2 record overall and their 11-0 conference record which has them right at the top of the ACC. They have been a great road team so far with their 6-0 road record this season. Meanwhile, Syracuse hasn't looked good in their games this season with their 10-12 record overall and their 4-7 conference record which has them near the bottom of the ACC. They have looked good on their home court with their 8-4 home record, but that hasn't helped them much in conference play. They have been really up and down on their home court lately and the ACC hasn't really been a strong conference this season. They are coming off a win over Cal in their last one, but they are 2-3 in their last 5 games. Now they face the best team in the ACC who is also ranked like one of the best teams in the nation and Duke just continues to crush conference opponents with the talent they have. They are coming off a 17 point win over UNC in their last one and they have a ton of momentum on their side with 15 wins in a row now, the only undefeated team in the ACC. Duke also has some really impressive wins going back before conference play started and there hasn't been a team in the ACC that has been able to keep up. Syracuse isn't going to make this a close game with the way they have played in the conference this year. The best way to place a bet here is on Duke to cover the spread in this game. 

Duke Syracuse Prediction:  Our NCAAB Pick for Wednesday, February 5, 2025 (7:00 pm ET start time) is Duke 86 Syracuse 62.

Don't miss our champion handicappers free picks and expert basketball picks today. And if you enjoyed this Duke Blue Devils Syracuse Orange prediction, be sure to drop by every day for our weekly NCAAB predictions and previews.

Duke Blue Devils: 26-17 ATS off a home win. 15-8 ATS off a home win against a conference rival. 27-18 ATS after playing a home game. 15-5 UNDER as a road favorite or pick. 11-4 UNDER in a road game where the total is 140 to 149.5. 17-3 UNDER after playing 2 consecutive home games.

Syracuse Orange: 17-27 ATS after 1 or more consecutive wins. 4-8 ATS when playing against a top-level team (Win Pct. > 80%). 5-9 ATS versus good passing teams, averaging 16 assists/game or more. 10-3 UNDER as a home underdog or pick. 12-3 UNDER versus good passing teams, averaging 16 assists/game or more. 28-19 UNDER versus good shooting teams - making 45% of their shots or more.

Duke Blue Devils:  None.

Syracuse Orange:  C. Westry (G) Questionable - Undisclosed. D. Freeman (F) Questionable - Lower Leg.

“Oh, by the way, it was our high in deflections. We talked about that and now we gotta break it again. Twenty-three, I think. One of you guys are gonna watch the film and see it was 16 or 17. I was told 23.” - Jon Scheyer after his team’s win against UNC in their last game. 

"We’ll probably know a little bit more very soon. Hopefully sometime this week about what’s the plan." - Adrian Autry on the injury to Donnie Freeman.

C. Flagg 

S. James 

K. Knueppel 

K. Maluach 

T. Proctor

J. Davis 

E. Lampkin 

E. Moore 

J. Starling 

L. Taylor

PPG: C. Flagg (20)

APG: C. Flagg (4.2)

Reb/G: C. Flagg (8)

PPG: J. Starling (17.9)

APG: J. Carlos (3.7)

Reb/G: E. Lampkin (9)

Coaches:

Duke Blue Devils: Jon Scheyer (3rd season)

Syracuse Orange: Adrian Autry (2nd season)