Detroit Pistons vs San Antonio Spurs Prediction, Preview and Odds - 03/05/2026

Game Time: 8:00 pm ET, Thursday, March 5, 2026

Venue:  Frost Bank Center, San Antonio, TX 

Where to Watch:  FDSDT, FDSSW

DraftKings:  Point Spread:  Pistons +2.5, Spurs -2.5; Over/Under:  227.5 points

Bet365:  Point Spread:  Pistons +3.5, Spurs -3.5; Over/Under:  227.5 points

BetMGM:  Point Spread:  Pistons +3.5, Spurs -3.5; Over/Under:  228.5 points

Detroit Pistons:  45-15 (1st place, Central Division)

San Antonio Spurs:  44-17 (1st place, Southwest Division)

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Detroit Pistons:  8-2 last 10

San Antonio Spurs:  9-1 last 10

The Pistons are entering this game with a 45-15 record overall this season and they are 21-8 in their road games this season where they will be in this game. They are entering this game off a loss against the Cleveland Cavaliers. Jalen Duren led the team in points in that game with 24 while Tobias Harris was next on the team with 19 points. Cade Cunningham led the team in assists in that game with 14 while Jalen Duren led the team in rebounds with 14. They were 50.6% from the field, 37.5% from 3-point range, and 75.9% from the free throw line with their shots in that game. Their offense is averaging 117.2 PPG and their defense is allowing their opponents to average 109.5 PPG against them. The Pistons have an ATS record of 31-29 this season and their O/U record is 26-33-1.

The Spurs are entering this game with a 44-17 record overall this season and they are 21-6 in their home games this season where they will be in this game. They are entering this game off a win against the Philadelphia 76ers. Devin Vassell and Dylan Harper each led the team in points in that game with 22 while Stephon Castle was next on the team with 15 points. Stephon Castle led the team in assists in that game with 10 while Carter Bryant and Keldon Johnson each led the team in rebounds with 9. They were 55.1% from the field, 40% from 3-point range, and 83.3% from the free throw line with their shots in that game. Their offense is averaging 118.2 PPG and their defense is allowing their opponents to average 111.4 PPG against them. The Spurs have an ATS record of 34-26-2 this season and their O/U record is 25-37.

The current betting odds have the Spurs listed as a 2.5 point favorite in this game according to Draftkings Sportsbook. The Spurs have looked great in their games this season with their 44-17 record overall which has them right near the top of the West with one of the best records in the entire NBA. They have looked great on their home court too with their 21-6 home record this season. Meanwhile, the Pistons have looked great in their games this season with their 45-15 record overall which has them right at the top of the East with one of the best records in the entire NBA. They have been a great road team too with their 21-8 road record this year. This is a matchup between two of the best teams in the NBA right now and both have been rolling in their games lately too. The Pistons are 8-2 in their last 10 games while the Spurs are 9-1, but the Spurs are off a huge win over the 76ers while the Pistons are off a loss to the Cavaliers. As good as the Pistons have looked lately, they have had some trouble against some better teams. They lost to the Cavs after almost losing to them on their own home court a few nights ago, and they also lost on their home court to the Spurs, struggling to even compete in that one. They could never get ahead in their game against the Spurs and now the Spurs are going to have the home advantage here. The Pistons will be looking to bounce back and get that game back that they lost to the Spurs at home, but the Spurs have been the hotter team lately and they are going to do the same thing they did to the Pistons in that last meeting. Look for the Spurs to roll the Pistons again with the help of the home crowd in this one. The best way to place a bet here is on the Spurs to cover the spread in this game. 

Pistons Spurs Prediction:  Our NBA Pick for Thursday, March 5, 2026 (8:00 pm ET start time) is Spurs 122 Pistons 112.

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Detroit Pistons: 18-7 ATS as a road underdog of 6 points or less. 12-5 ATS revenging a straight up loss vs opponent as a home favorite. 24-17 ATS after a loss by 6 points or less. 4-0 OVER off an upset loss to a division rival as a favorite.

San Antonio Spurs: 16-26 ATS off a road win. 4-7 ATS at home versus good rebounding teams - outrebounding opponents by 3+ per game. 5-1 OVER at home after allowing 100 points or less. 8-4 OVER at home versus good rebounding teams - outrebounding opponents by 3+ per game. 

Detroit Pistons:  None.

San Antonio Spurs:  H. Barnes (PF) Day To Day - Ankle. M. Plumlee (C) Day To Day - Reconditioning. D. Jones Garcia (SF) Out For Season - Ankle.

"I have no response. If you mean it, you don't say it anonymously.” - J.B. Bickerstaff on the comments about his team from an anonymous Cavaliers player.

“What happened in New York, I think we wanted to prove to everyone that we’re still here.” - Dylan Harper after their win against the 76ers in their game on Tuesday.

PG Cade Cunningham

SG Duncan Robinson

SF Ausar Thompson

PF Tobias Harris

C Jalen Duren

PG De'Aaron Fox

SG Stephon Castle

SF Devin Vassell

PF Julian Champagnie

C Victor Wembanyama

PPG: Cade Cunningham (25.2)

APG: Cade Cunningham (9.9)

Reb/G: Jalen Duren (10.8)

PPG: Victor Wembanyama (23.4)

APG: Stephon Castle (6.8)

Reb/G: Victor Wembanyama (11.1)

Coaches:

Detroit Pistons: J.B. Bickerstaff (2nd season)

San Antonio Spurs: Mitch Johnson (2nd season)