Detroit Lions vs Washington Commanders Prediction, Preview and Odds - 11/09/2025

by Rod Pearson

Friday, Nov 07, 2025
Game Time: 4:25 pm ET, Sunday, November 9, 2025
Venue:  Northwest Stadium, Landover, MD
Where to Watch:  FOX


Opening Odds at USA Sportsbooks

DraftKings:  Point Spread:  Lions -7.5, Commanders +7.5; Over/Under:  49.5 points
Bet365:  Point Spread:  Lions -8, Commanders +8; Over/Under:  49 points
BetMGM:  Point Spread:  Lions -8, Commanders +8; Over/Under:  49 points

Season Record

Detroit Lions:  5-3 (2nd place, NFC North)
Washington Commanders:  3-6 (3rd place, NFC East)

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Recent Form
Detroit Lions:  lost their last game at home against the Minnesota Vikings 27-24.
Washington Commanders:  lost their last game at home against the Seattle Seahawks 38-14.


Detroit Lions vs Washington Commanders Preview and Analysis


The Lions are entering this game with a 5-3 record overall and they have a 1-2 record in their divisional games too. They are 3-1 in their home games, 2-2 in their road games, and they are also 1-0 in their neutral site games this season, but they will be on the road for this game. They lost their last game against the Minnesota Vikings 27-24. Jared Goff was the starting QB and he completed 25/37 passes for 284 passing yards, 2 touchdowns, and 0 interceptions. David Montgomery led the team in rushing yards with 40 and 1 TD. Amon-Ra St. Brown led the receivers with 97 receiving yards on 9 receptions. Jack Campbell led the defense in that game with 6 solo tackles and 3 assisted tackles while Jack Campbell, Derrick Barnes, Aidan Hutchinson, Al-Quadin Muhammad, and Tyler Lacy each led the defense in sacks with 1. Terrion Arnold came away with the only interception for them in that one.
 
 
 
The Commanders are entering this game with a 3-6 record overall and they have a 1-1 record in their divisional games too. They are 2-2 in their home games, 1-4 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They lost their last game against the Seattle Seahawks 38-14. Jayden Daniels was the starting QB and he completed 16/22 passes for 153 passing yards, 0 touchdowns, and 1 interception. Chris Rodriguez Jr. led the team in rushing yards with 65 and 1 TD. Zach Ertz led the receivers with 46 receiving yards on 4 receptions. Frankie Luvu and Trey Amos each led the defense in that game with 4 solo tackles and 3 assisted tackles while no one on the defense recorded a sack for them. Mike Sainristil came away with the only interception for them in that one.


Lions vs Commanders Prediction

The current betting odds have the Lions listed as a 7.5 point favorite in this game according to Draftkings Sportsbook. The Lions have looked good in their games this season with their 5-3 record overall which has them right near the top of the NFC North. They are off a 27-24 loss to the Vikings at home in their last one and they haven't looked as good in their road games this year with their 2-2 road record, but they will be looking to bounce back after that divisional loss. Meanwhile, the Commanders haven't looked good in their games this season with their 3-6 record overall which has them right near the bottom of the NFC East. They are off a 38-14 loss to the Seahawks in their last one and they lost a few players to injury in that game, including their starting QB. They have looked terrible in their games lately as they have been in a big slump, and it isn't going to get any easier for them with the players they are missing. Their defense hasn't looked good all season either and that is going to be an issue against one of the best offenses in the NFL. Not only will the Lions be looking to bounce back from their loss to the Vikings, they will also be coming for their revenge here since the Commanders were the team that kicked them out of the playoffs last year. All signs point to the Lions crushing the Commanders in this one. The best way to place a bet here is on the Lions to cover the spread in this game. 

Lions Commanders Prediction:  Our NFL Pick for Sunday, November 9, 2025 (4:25 pm ET start time) is Lions 35 Commanders 10.
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NFL Betting Trends


Detroit Lions: 31-15 ATS in all games. 12-2 ATS as a road favorite. 5-0 ATS off an upset loss as a favorite. 6-1 ATS after a 2 game home stand. 27-18 OVER in all games. 17-7 OVER as a favorite of 3.5 to 9.5 points. 6-1 OVER after a 2 game home stand.

Washington Commanders: 1-5 ATS as a home underdog. 6-11 ATS vs. good offensive teams - scoring 24 or more points/game. 6-11 ATS versus good offensive teams - averaging 350 yards/game or more. 12-3 OVER as an underdog of 3.5 to 9.5 points. 5-0 OVER after scoring 14 points or less last game.

Key Injuries


Detroit Lions:  T. Decker (OT) Injured - Shoulder. D. Skipper (OT) Injured - Back. P. O'Connor (DL) Injured - Knee. D. Thomas (S) Injured - Forearm. G. Stuard (LB) Injured - Foot. J. Paschal (DL) Injured - Back. T. Summers (LB) Injured - Hand. M. Rodriguez (LB) Injured - Knee. J. Saylors (RB) Injured - Back. P. Sewell (OT) Injured - Shoulder. K. Joseph (S) Injured - Knee. C. Reynolds (RB) Injured - Hamstring. T. Arnold (CB) Injured - Shoulder. M. Frazier (OG) Injured - Knee.

Washington Commanders:  T. Amos (CB) Injured - Hip. J. Daniels (QB) Injured - Elbow. J. Croskey-Merritt (RB) Injured - Tooth. B. Wagner (LB) Injured - Thumb. L. Tunsil (OT) Injured - Hamstring. E. Goldman (DL) Injured - Concussion. T. McLaurin (WR) Injured - Quad. Q. Martin (S) Injured - Hamstring. T. Owens (S) Injured - Hamstring. C. Yankoff (TE) Injured - Hamstring. J. Newton (DL) Injured - Ankle. Z. Ertz (TE) Injured - NIR - Rest. V. Miller (LB) Injured - NIR - Rest.

Notable Quotes


“We did everything we needed to do to lose that game. We made every critical error at the right time to lose.” - Dan Campbell after his team’s loss against the Vikings in their last game. 


“Just an unacceptable performance by us tonight. We missed it by a mile.” - Dan Quinn after his team’s loss against the Seahawks in their last game. 


Starting Lineups


Detroit Lions
WR Raymond, Kalif
WR Williams, Jameson
WR St. Brown, Amon-Ra
TE LaPorta, Sam
QB Goff, Jared
RB Gibbs, Jahmyr

Washington Commanders
WR Burks, Treylon
WR Moore, Chris
WR Samuel, Deebo
TE Ertz, Zach
QB Mariota, Marcus
RB Croskey-Merritt, Jacory

Statistical Leaders


Detroit Lions
Passing: Jared Goff (1,915)
Rushing: Jahmyr Gibbs (551)
Receiving: Amon-Ra St. Brown (635)
Touchdowns: Jahmyr Gibbs (7)

Washington Commanders
Passing: Jayden Daniels (1,184)
Rushing: Jacory Croskey-Merritt (440)
Receiving: Deebo Samuel (367)
Touchdowns: Deebo Samuel (4)

Coaches:
Detroit Lions: Dan Campbell (5th season)
Washington Commanders: Dan Quinn (2nd season)


Rod Pearson

About the Author:

Rod Pearson has been a rabid sports fan his entire life.  He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years.  In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective.  Join Rod every day as he breaks down the games to find the best betting value.

All photographic images used for editorial content have been licensed from the Associated Press.

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