by Rod Pearson
Friday, Nov 14, 2025
Game Time: 8:20 pm ET, Sunday, November 16, 2025
Venue: Lincoln Financial Field, Philadelphia, PA
Where to Watch: NBC, Peacock
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: Lions +2.5, Eagles -2.5; Over/Under: 46.5 points
Bet365: Point Spread: Lions +2.5, Eagles -2.5; Over/Under: 46.5 points
BetMGM: Point Spread: Lions +2.5, Eagles -2.5; Over/Under: 46.5 points
Season Record
Detroit Lions: 6-3 (1st place, NFC North)
Philadelphia Eagles: 7-2 (1st place, NFC East)
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Detroit Lions: won their last game on the road against the Washington Commanders 44-22.
Philadelphia Eagles: won their last game on the road against the Green Bay Packers 10-7.
Detroit Lions vs Philadelphia Eagles Preview and Analysis
The Lions are entering this game with a 6-3 record overall and they have a 1-2 record in their divisional games too. They are 3-1 in their home games, 3-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against the Washington Commanders 44-22. Jared Goff was the starting QB and he completed 25/33 passes for 320 passing yards, 3 touchdowns, and 0 interceptions. Jahmyr Gibbs led the team in rushing yards with 142 and 2 TDs. Jameson Williams led the receivers with 119 receiving yards on 6 receptions and 1 TD. Thomas Harper led the defense in that game with 6 solo tackles and 0 assisted tackles while Brian Branch led the defense in sacks with 1.5. No one on the defense came away with an interception for them in that one.
The Eagles are entering this game with a 7-2 record overall and they have a 2-1 record in their divisional games too. They are 3-1 in their home games, 4-1 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against the Green Bay Packers 10-7. Jalen Hurts was the starting QB and he completed 15/26 passes for 183 passing yards, 1 touchdown, and 0 interceptions. Saquon Barkley led the team in rushing yards with 60. DeVonta Smith led the receivers with 69 receiving yards on 4 receptions and 1 TD. Nakobe Dean led the defense in that game with 6 solo tackles and 1 assisted tackle while Nakobe Dean, Jalyx Hunt, and Nolan Smith Jr. each led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.
Lions vs Eagles Prediction
The current betting odds have the Eagles listed as a 2.5 point favorite in this game according to Draftkings Sportsbook. The Eagles have looked great in their games this season with their 7-2 record overall which has them right at the top of the NFC East with one of the best records in the NFL. They are off a 10-7 win over the Packers in their last one and they continue to show why they are the defending Super Bowl champions, winning games in many different ways this season. Meanwhile, the Lions have looked good in their games this season with their 6-3 record overall which has them right at the top of the NFC North. They are off a 44-22 win over the Commanders in their last one and that was a nice bounce back win for them, but they are only 3-2 in road games this season and have struggled more in those. They are going to bring their best effort for the Eagles as this is a good litmus test for them, but they have fallen short this year in some of their bigger games. The Eagles defense didn't look great to start the year, but they have fixed the issues they were dealing with and now look like one of the best defenses in the NFL lately. The offense hasn't looked great at times, but they still have a lot of talent to work with and they continue to find ways to win games like champions usually do. The Eagles are still the better team here, finding ways to get the job done, and they have the edge being at home. The best way to place a bet here is on the Eagles to cover the spread in this game.
Lions Eagles Prediction: Our NFL Pick for Sunday, November 16, 2025 (8:20 pm ET start time) is Eagles 23 Lions 17.
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NFL Betting Trends
Detroit Lions: 32-15 ATS in all games. 18-5 ATS in road games. 22-11 ATS against conference opponents. 28-18 OVER in all games. 19-8 OVER in all games where the total is between 42.5 and 49 points.
Philadelphia Eagles: 36-48 ATS in a home game where the total is greater than or equal to 45.5. 1-4 ATS at home after 3 or more consecutive wins against the spread. 9-5 OVER off a road win. 5-1 OVER after playing on Monday night football.
Key Injuries
Detroit Lions: A. Robertson (CB) Injured - Hamstring. T. Decker (OT) Injured - Shoulder. G. Glasgow (OG) Injured - Back. P. O'Connor (DL) Injured - Knee. M. Davenport (DL) Injured - Shoulder. D. Reed (CB) Injured - Hamstring. J. Paschal (DL) Injured - Back. B. Wright (TE) Injured - Ankle. M. Rodriguez (LB) Injured - Knee. J. Saylors (RB) Injured - Back. A. Hutchinson (DL) Injured - Elbow. P. Sewell (OT) Injured - Ankle. K. Joseph (S) Injured - Knee. S. LaPorta (TE) Injured - Back. T. Arnold (CB) Injured - Concussion. S. Vaki (RB) Injured - Ankle. M. Frazier (OG) Injured - Knee.
Philadelphia Eagles: L. Johnson (OT) Injured - Ankle. L. Dickerson (OG) Injured - Quad. C. Adomitis (LS) Injured - Finger. C. Jurgens (OG) Injured - Knee. T. Steen (OG) Injured - Oblique. N. Smith Jr. (LB) Injured - Triceps. J. Bennett (CB) Injured - Pectoral. W. Lampkin (OG) Injured - Knee. D. Cooper (WR) Injured - Shoulder.
Notable Quotes
"Listen, John Morton's all team. That's all he cares about. He just wants to win. He wants to be a part of it. He wants to help where he can, and he was outstanding today.” - Dan Campbell on taking over play calling duties.
“He loves football. He loves working. You could just see it, the way he was running around in practice. His motor is constantly, constantly running.” - Nick Sirianni after his team’s win against the Packers in their last game.
Starting Lineups
Detroit Lions
WR Raymond, Kalif
WR Williams, Jameson
WR St. Brown, Amon-Ra
TE LaPorta, Sam
QB Goff, Jared
RB Gibbs, Jahmyr
Philadelphia Eagles
WR Brown, A.J.
WR Smith, DeVonta
WR Dotson, Jahan
TE Goedert, Dallas
QB Hurts, Jalen
RB Barkley, Saquon
Statistical Leaders
Detroit Lions
Passing: Jared Goff (2,235)
Rushing: Jahmyr Gibbs (693)
Receiving: Amon-Ra St. Brown (693)
Touchdowns: Jahmyr Gibbs (10)
Philadelphia Eagles
Passing: Jalen Hurts (1,860)
Rushing: Saquon Barkley (579)
Receiving: DeVonta Smith (657)
Touchdowns: Dallas Goedert (7)
Coaches:
Detroit Lions: Dan Campbell (5th season)
Philadelphia Eagles: Nick Sirianni (5th season)
Rod Pearson
About the Author:
Rod Pearson has been a rabid sports fan his entire life. He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years. In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective. Join Rod every day as he breaks down the games to find the best betting value.
