by Rod Pearson
Thursday, Dec 11, 2025
Game Time: 4:25 pm ET, Sunday, December 14, 2025
Venue: SoFi Stadium, Inglewood, CA
Where to Watch: FOX
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: Lions +6, Rams -6; Over/Under: 55.5 points
Bet365: Point Spread: Lions +6, Rams -6; Over/Under: 55 points
BetMGM: Point Spread: Lions +6, Rams -6; Over/Under: 55.5 points
Season Record
Detroit Lions: 8-5 (3rd place, NFC West)
Los Angeles Rams: 10-3 (1st place, NFC West)
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Recent Form
Detroit Lions: won their last game at home against the Dallas Cowboys 44-30.
Los Angeles Rams: won their last game on the road against the Arizona Cardinals 45-17.
Detroit Lions vs Los Angeles Rams Preview and Analysis
The Lions are entering this game with an 8-5 record overall and they have a 1-3 record in their divisional games too. They are 5-2 in their home games, 3-3 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They won their last game against the Dallas Cowboys 44-30. Jared Goff was the starting QB and he completed 25/34 passes for 309 passing yards, 1 touchdown, and 0 interceptions. David Montgomery led the team in rushing yards with 60 and 1 TD. Jameson Williams led the receivers with 96 receiving yards on 7 receptions. D.J. Reed led the defense in that game with 8 solo tackles and 0 assisted tackles while Al-Quadin Muhammad led the defense in sacks with 3. D.J. Reed and Derrick Barnes each came away with 1 interception for them in that one.
The Rams are entering this game with a 10-3 record overall and they have a 3-1 record in their divisional games too. They are 5-1 in their home games, 4-2 in their road games, and they are also 1-0 in their neutral site games this season, but they will be at home for this game. They won their last game against the Arizona Cardinals 45-17. Matthew Stafford was the starting QB and he completed 22/31 passes for 281 passing yards, 3 touchdowns, and 0 interceptions. Blake Corum led the team in rushing yards with 128 and 2 TDs. Puka Nacua led the receivers with 167 receiving yards on 7 receptions and 2 TDs. Omar Speights led the defense in that game with 4 solo tackles and 1 assisted tackle while Kamren Curl, Byron Young, and Kobie Turner each led the defense in sacks with 1. Nate Landman came away with the only interception for them in that one.
Lions vs Rams Prediction
The current betting odds have the Lions listed as a 6 point underdog in this game according to Draftkings Sportsbook. The Lions have looked good in their games this season with their 8-5 record overall, but that record has them right near the bottom of the NFC North in a competitive division. They haven't been a great road team this season with their 3-3 road record. Meanwhile, the Rams have looked great in their games this season with their 10-3 record overall which has them right at the top of the NFC West. They have been a great home team too with their 5-1 home record this year. The Rams are off a 45-17 win over the Cardinals in their last one and they have been rolling in their games lately, but they did slip up against the Panthers 2 weeks ago. They have looked like one of the best teams in the NFL for a lot of the season, but the Lions are also a really good team and they are going to be desperate to win this game. The Lions are off a 44-30 win over the Cowboys in their last one and they played on Thursday night so they have some extra time to rest too. Their defense hasn't looked great this year, but they still have one of the best offenses in the NFL and they can go toe-to-toe with this Rams team. The Rams need this game too with how tight their division is, but the Lions could end up missing the playoffs with a loss here so they are going to bring their best effort and leave everything on the field against one of the best teams in the NFL. The best way to place a bet here is on the Lions to cover the spread in this game.
Lions Rams Prediction: Our NFL Pick for Sunday, December 14, 2025 (4:25 pm ET start time) is Rams 34 Lions 30.
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NFL Betting Trends
Detroit Lions: 33-18 ATS in all games. 7-2 ATS after allowing 30 points or more last game. 10-5 ATS vs. good offensive teams - scoring 24 or more points/game. 31-19 OVER in all games. 10-5 OVER after a win by 14 or more points.
Los Angeles Rams: 2-5 ATS at home off a road win. 4-7 ATS at home after playing their last game on the road. 1-6 ATS at home versus good offensive teams - averaging 350 yards/game or more. 7-4 OVER after a win by 14 or more points. 7-3 OVER vs. good teams - outscoring opponents by 6+ PPG on the season.
Key Injuries
Detroit Lions: T. Decker (OT) Injured - Shoulder. A. Anzalone (LB) Injured - Illness. K. Raymond (WR) Injured - Ankle. K. Awosika (OG) Injured - Foot. K. Joseph (S) Injured - Knee. B. Branch (CB) Injured - Achilles. S. Zylstra (TE) Injured - Knee. T. Harper (S) Injured - Concussion. C. Mahogany (OG) Injured - Fibula. S. Vaki (RB) Injured - Thumb.
Los Angeles Rams: D. Adams (WR) Injured - Hamstring. D. Williams (CB) Injured - Tibia. T. Atwell (WR) Injured - Hamstring. B. Young (LB) Injured - Knee.
Notable Quotes
“He’s unique. He’s special.” - Dan Campbell on Jahmyr Gibbs after his team’s win against the Cowboys in their last game.
“I thought Matthew was outstanding. He was great — thought he saw the field really well. He threw the ball with accuracy and anticipation.” - Sean McVay after his team’s win against the Cardinals in their last game.
Starting Lineups
Detroit Lions
WR TeSlaa, Isaac
WR Williams, Jameson
WR St. Brown, Amon-Ra
TE Firkser, Anthony
QB Goff, Jared
RB Gibbs, Jahmyr
Los Angeles Rams
WR Adams, Davante
WR Nacua, Puka
WR Smith, Xavier
TE Parkinson, Colby
QB Stafford, Matthew
RB Williams, Kyren
Statistical Leaders
Detroit Lions
Passing: Jared Goff (3,334)
Rushing: Jahmyr Gibbs (1,062)
Receiving: Amon-Ra St. Brown (976)
Touchdowns: Jahmyr Gibbs (16)
Los Angeles Rams
Passing: Matthew Stafford (3,354)
Rushing: Kyren Williams (952)
Receiving: Puka Nacua (1,186)
Touchdowns: Davante Adams (14)
Coaches:
Detroit Lions: Dan Campbell (5th season)
Los Angeles Rams: Sean McVay (9th season)
Rod Pearson
About the Author:
Rod Pearson has been a rabid sports fan his entire life. He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years. In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective. Join Rod every day as he breaks down the games to find the best betting value.
