Cleveland Guardians vs Chicago White Sox Prediction, Preview and Odds - 07/22/2022

by Rod Pearson

Thursday, Jul 21, 2022
Game Time: 8:10 pm ET, Friday, July 22, 2022
Venue:  Guaranteed Rate Field, Chicago, IL
Where to Watch:  Apple TV+

 

Opening Odds at USA Sportsbooks

DraftKings:  Moneyline odds:  Guardians +135, White Sox -155; Over/Under:  8.5 runs
Bet365:  Moneyline odds:  Guardians +130, White Sox -150; Over/Under:  8.5 runs
BetMGM:  Moneyline odds:  Guardians +125, White Sox -150; Over/Under:  8.5 runs
 

Season Record

Cleveland Guardians:  46-44 (2nd place, AL Central)
Chicago White Sox:  46-46 (3rd place, AL Central)
 
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Recent Form
Cleveland Guardians:  6-4 last 10
Chicago White Sox:  7-3 last 10
 
 
 

Cleveland Guardians vs Chicago White Sox Preview and Analysis

 
The Guardians enter this game on a 3 game winning streak. They won their last series against the Detroit Tigers 3-0 completing the sweep in a 3-game series. They enter this game with a 46-44 record overall and have a road record of 21-25. This is the series opener of a 4-game series with the White Sox on Friday. Their offense ranks 16th in the MLB with a .698 OPS. Cal Quantrill was their starting pitcher on Sunday while Cal Quantrill is making his start in this game on Friday. He is 6-5 with a 3.75 ERA this season. His team won their last 2 straight games this season with him making an appearance. In his last start, he allowed 0 ER, 0 HRs, and 2 BB with 5 Ks on 4 hits through 6 IP against the Detroit Tigers. 
 
The White Sox won 5 of their last 6 games and enter this game off of a win. They won their last series against the Minnesota Twins 3-1 in a 4-game series. They enter this game with a 46-46 record overall and have a home record of 19-25. This is the 1st game of a 4-game series with the Guardians on Friday. Their offense ranks 18th in the MLB with a .696 OPS. Dylan Cease was on the mound on Sunday while Lucas Giolito will be throwing the first pitch in this game on Friday. He is 6-5 with a 4.69 ERA this season. His team won 2 of their last 3 games this season with him making an appearance. In his last start, he allowed 0 ER, 0 HRs, and 1 BB with 5 Ks on 5 hits through 6.1 IP against the Cleveland Guardians.

 

Guardians vs White Sox Prediction

The current betting odds have not been listed for this game yet. The White Sox entered the All-Star break playing very well as they were able to get a series win against the Twins in a 4-game series, really cutting down on that lead they have in the AL Central right now. The White Sox were getting very hot last week, their pitching has been a lot better in their recent games as they are not allowing as many runs anymore. Their batting has also been a lot better as they were scoring a lot of runs in their games and really overpowering teams with their offense. The Guardians were also scoring a lot of runs in their games prior to the break but they were also at home to one of the worst offensive teams in the MLB, the Detroit Tigers. They also faced the White Sox in a 4-game series at home before that which they split but the White Sox won the last 2 games of that series and have been a lot better since those games. The White Sox will be looking to carry over that play into the 2nd half of the season as they are still in position to win the AL Central. The best way to place a bet in this game is on the White Sox to win here.
 
Guardians White Sox Prediction:  Our MLB Pick for Friday, July 22, 2022 (8:10 pm ET start time) is White Sox 6 Guardians 4.
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MLB Betting Trends

 
Cleveland Guardians: Will be posted by 12:00am EST, 07/22/2022.
Chicago White Sox: Will be posted by 12:00am EST, 07/22/2022.
 

Key Injuries

 
Cleveland Guardians:  O. Gonzalez (LF) Late July - Ribs. A. Gimenez (SS) Ques Fri - Foot. A. Civale (SP) Out indefinitely - Wrist.
Chicago White Sox:  L. Robert (CF) Late July - Illness. E. Jimenez (LF) Late July - Leg. J. Burger (3B) Late July - Hand.
 
 

Notable Quotes

 
"Just a really good player. It doesn't matter if it's on the bases, or wherever. He impacts the game everywhere for us. Sometimes in a really big way." - Terry Francona after his team’s win against the Tigers on Sunday.
 
 
"That's what he's done all year. He's picked us up at important times." - Tony La Russa on Cease after his team’s win against the Twins on Sunday.
 
 

Starting Lineups

 
Cleveland Guardians
Steven Kwan (L) LF
Amed Rosario (R) SS
Jose Ramirez (S) 3B
Josh Naylor (L) 1B
Andres Gimenez (L) 2B
Franmil Reyes (R) DH
Nolan Jones (L) RF
Luke Maile (R) C
Myles Straw (R) CF
 
Chicago White Sox
Tim Anderson (R) SS
Yoan Moncada (S) 3B
Andrew Vaughn (R) 1B
Jose Abreu (R) DH
Gavin Sheets (L) RF
Josh Harrison (R) 2B
Leury Garcia (S) LF
Seby Zavala (R) C
Adam Engel (R) CF
 

Statistical Leaders

 
Cleveland Guardians
Batting Average:  Nolan Jones (.333)
Hits:  Amed Rosario (99)
Home Runs:  Jose Ramirez (19)
RBI:  Jose Ramirez (75)
Stolen Bases:  Jose Ramirez (13)
Wins:  Triston McKenzie (7)
Saves:  Emmanuel Clase (19)
ERA:  Ian Gibaut (0.00)
 
Chicago White Sox
Batting Average:  Tim Anderson (.310)
Hits:  Jose Abreu (105)
Home Runs:  Luis Robert (12)
RBI:  Luis Robert (54)
Stolen Bases:  Luis Robert (11)
Wins:  Dylan Cease (9)
Saves:  Liam Hendriks (18)
ERA:  Dylan Cease (2.15)
 
Managers:
Cleveland Guardians: Terry Francona (10th season)
Chicago White Sox: Tony La Russa (2nd season)


Rod Pearson

About the Author:

Rod Pearson has been a rabid sports fan his entire life.  He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years.  In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective.  Join Rod every day as he breaks down the games to find the best betting value.

All photographic images used for editorial content have been licensed from the Associated Press.

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