Cleveland Cavaliers vs Boston Celtics Prediction, Preview and Odds - 12/22/2021

by Amedeus Mastrangelo

Wednesday, Dec 22, 2021
Game Time: 7:30 pm ET, Wednesday, December 22, 2021
Venue:  TD Garden, Boston, MA 
Where to Watch:  NBCS-BOS

 

Opening Odds at USA Sportsbooks

DraftKings:  Point Spread:  Cavaliers +6, Celtics -6; Over/Under:  NL points
Bet365:  Point Spread:  Cavaliers 5.5, Celtics 5.5; Over/Under:  NL points
BetMGM:  Point Spread:  Cavaliers +6.5, Celtics -6.5; Over/Under:  NL points
 

Season Record

Cleveland Cavaliers:  19-12 (2nd place, Central Division)
Boston Celtics:  15-16 (3rd place, Atlantic Division)
 
Do not miss out on our expert handicapper analysis! Ben Burns is on a 9-1 (10*) RUN! Make sure you check out his picks and many more from the expert handicappers featured in the Shop Picks section.

 

Cleveland Cavaliers vs Boston Celtics Preview and Analysis

 
Recent Form
Cleveland Cavaliers:  8-2 last 10
Boston Celtics:  4-6 last 10
 
 
 

Cleveland Cavaliers Analysis

The Cavaliers are coming into this game with a 19-12 record overall and they are 10-5 in their road games this season where they will be in this game. Their last loss was against the Milwaukee Bucks but they have gone on a six-game winning streak since then with wins coming against the Chicago Bulls, the Minnesota Timberwolves, the Sacramento Kings, the Miami Heat, the Houston Rockets, and the Bucks in their last game. Cedi Osman led the team in points in that game off the bench with 23 while Darius Garland was next on the team with 22 points. Ricky Rubio led the team in assists in that game with 10 while Kevin Love led the team in rebounds with 7. They were 50% from the field, 35.6% from 3-point range, and 92.9% from the free throw line with their shooting in that game. Their offense is averaging 107 PPG and their defense is allowing their opponents to average 101.1 PPG against them. The Cavs have an ATS record of 24-5-2 this season and their O/U record is 11-20.
 
 

Boston Celtics Analysis

The Celtics are coming into this contest with a 15-16 record overall and they are 8-6 in their home games this season where they will be in this game. They have lost 2 of their last 3 games and are coming into this one off of a loss in their last game. Their last win was against the New York Knicks while their 2 losses in that span came against the Golden State Warriors and the Philadelphia 76ers in their last game. Jaylen Brown went off in that game as he led the team in points with 30 while Jayson Tatum was next on the team with 17 points. Tatum led the team in assists in that game with 6 while Enes Freedom led the team in rebounds with 11. They were 46.3% from the field, 25.9% from 3-point range, and 80% from the free throw line with their shots in that game. Their offense is averaging 108.3 PPG and their defense is allowing their opponents to average 107.3 PPG against them. The Celtics have an ATS record of 15-14-2 this season and their O/U record is 13-17-1.
 
 

 

Cavaliers vs Celtics Prediction

The Cavaliers are coming into this matchup as a 6 point underdog with the current betting odds according to Draftkings Sportsbook. The Cavaliers have been having a great season and are playing very well in their recent games. The Cavs have won 6 straight games and they have a winning record on the road this season. They also have the best ATS record in the NBA and are the only team covering in over 80% and 70% of their games. The Celtics have been playing alright but they have been a lot more inconsistent in their games this season and they even sit at below .500 for the year. The best bet to place in this game is on the Cavaliers to cover the spread here as they have a very good chance of winning this game.
 
Cavaliers Celtics Prediction:  Our NBA Pick for Wednesday, December 22, 2021 (7:30 pm ET start time) is Cavaliers 107 Celtics 99.
Don't miss our champion handicappers free picks and expert basketball picks today.  And if you enjoyed this Cleveland Cavaliers Boston Celtics prediction, be sure to drop by every day for our weekly NBA predictions and previews.
 

NBA Betting Trends

 
Cleveland Cavaliers: 11-20 O/U in all games. 11-20 O/U in the first half of the season. 2-5 O/U when playing only their 2nd game in 5 days. 6-13 O/U after 1 or more consecutive unders. 3-7 O/U off a win against a division rival. 10-27 O/U after allowing 100 points or less. 6-17 O/U after allowing 105 points or less 2 straight games. 4-14 O/U after 1 or more consecutive wins.
Boston Celtics: 18-10 ATS in December games. 15-8 ATS after 2 consecutive division games. 16-4 ATS after having lost 5 or 6 of their last 7 games. 51-29 ATS off an upset loss to a division rival as a favorite. 28-16 ATS off an upset loss as a favorite. 10-2 ATS after scoring 105 points or less.
 

Key Injuries

 
Cleveland Cavaliers:  D. Valentine (SG) Out indefinitely - Illness. D. Windler (SG) Out indefinitely - Head injury. R. Nembhard (PG) Out indefinitely - Illness. L. Stevens (PF) Out indefinitely - Illness. Jarrett Allen (C) Out indefinitely - Illness. Evan Mobley (C) Out indefinitely - Hip injury. Isaac Okoro (SF) Out indefinitely - Illness. Collin Sexton (PG) out for season - Knee injury.
Boston Celtics:  R. Williams III (C) Ques Wed - Personal. Brodric Thomas (PG) Out indefinitely - Illness. Josh Richardson (SG) Out indefinitely - Illness. B. Fernando (PF) Out indefinitely - Back injury. Sam Hauser (SF) Out indefinitely - Illness. Juancho Hernangomez (PF) Out indefinitely - Illness. Grant Williams (PF) Out indefinitely - Illness. Al Horford (C) Out indefinitely - Illness. Jabari Parker (PF) Out indefinitely - Illness.
 
 

Notable Quotes

 
 
"In order to be successful against Milwaukee, you have to move the ball. They did a really good job of creating shots for each other." - J.B. Bickerstaff on his team’s win against the Bucks on Saturday night.
 
"We just had a little lapse there and picked it up where we left off in the first half. A few mistakes there, but overall three great quarters of defense." - Ime Udoka on his team’s win against the Knicks on Saturday night.
 
 

Starting Lineups

 
Cleveland Cavaliers
PG    Darius Garland 
SG    Cedi Osman
SF    Lauri Markkanen
PF    Dean Wade
C    Kevin Love
 
Boston Celtics
PG    Dennis Schroder
SG    Marcus Smart
SF    Jaylen Brown
PF    Jayson Tatum
C    Robert Williams III
 

Statistical Leaders

 
Cleveland Cavaliers
PPG: D. Garland (19.1)
APG: D. Garland (7.3)
Reb/G: J. Allen (10.8)
 
Boston Celtics
PPG: J. Tatum (25.9)
APG: M. Smart (5.5)
Reb/G: J. Tatum (8.6)
 
Coaches:
Cleveland Cavaliers: J.B. Bickerstaff (3rd season)
Boston Celtics: Ime Udoka (1st season)
 


Amedeus Mastrangelo

About the Author:

Amedeus Mastrangelo has been heavily wagering on all sports for years and plays just about everything, including sides, totals, favorites, underdogs, against the spread, alternative spreads, first half, second half, player props, and futures. The bottom line is, if Mastrangelo can see an edge in any way shape or form, then he's going to take advantage.

All photographic images used for editorial content have been licensed from the Associated Press.

© 2025 Al McMordie's BigAl.com. All Rights Reserved.