Game Time: 8:10 pm ET, Wednesday, September 29, 2021
Venue: Guaranteed Rate Field, Chicago, IL
Where to Watch: NBCS-CHI
Opening Odds at USA Sportsbooks
DraftKings: Moneyline odds: Reds +155, White Sox -180; Over/Under: 8 runs
Bet365: Moneyline odds: Reds +150, White Sox -170; Over/Under: 8 runs
BetMGM: Moneyline odds: Reds +150, White Sox -185; Over/Under: 8 runs
Cincinnati Reds: 82-75 (3rd place, NL Central)
Chicago White Sox: 89-68 (1st place, AL Central)
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Cincinnati Reds vs Chicago White Sox Preview and Analysis
Cincinnati Reds: 6-4 last 10
Chicago White Sox: 5-5 last 10
Cincinnati Reds Analysis
The Reds are coming into this game after winning a 1-off game against the Pittsburgh Pirates on Monday 13-1. They are now on a 4 game winning streak after taking 3 of the four-game series against the Washington Nationals over the weekend. They will be playing a two-game series against the White Sox with the series opener being on Tuesday. That Tuesday game has not been played yet so the result is still pending. This will be the series finale on Wednesday. Rookie pitcher Riley O'Brien was given the nod for Tuesday's game while Sonny Gray will be the starting pitcher on the mound in this game on Wednesday. He is 7-8 with a 3.99 ERA this season. He has been credited with 2 straight losses and his team has lost 3 of the last 4 games that he has started in. In his last start, he allowed 4 ER, 2 of them being homers, and 4 BB with 3 Ks on 5 hits through 4 IP against the Nats last Friday. He has seen the White Sox lineup just 1 time this season in a game that was a no-decision for him but his team went on to win 1-0 as he allowed 0 runs in the game. Their offense has scored 39 runs in their last 5 games averaging almost 8 runs scored per game in that span and they have allowed their opponents to score 19 runs against them in that same span allowing almost 4 runs per game.
Chicago White Sox Analysis
The White Sox are coming into this game after winning a 1-off game against the Detroit Tigers on Monday night 8-7. They are on a 2 game winning streak now and have won 3 of their last 4 games. The first game of their two-game series against the Reds is on Tuesday with that result still pending. This will be the 2nd and final game of that series on Wednesday. Reynaldo Lopez will be the starter on Tuesday while Carlos Rodon will be throwing the first pitch for his team in this game on Wednesday. He is 12-5 with a 2.47 ERA this season and he has the 2nd most wins on his team for a starting pitcher in the rotation this season. He has been credited with 4 straight wins and his team has won 4 of the last 5 games that he has started in. In his last start, he allowed 3 runs, 2 of them being earned, and 2 BB with 6 strikeouts on 2 hits through 3 innings of work against the Tigers on Monday last week. This will be his first time facing the Reds lineup this season as these two teams are in opposite leagues so they do not meet up that often. Their offense has scored 24 runs in their last 5 games averaging almost 5 runs scored per game in that span and they have allowed their opponents to score 22 runs against them in that same span allowing a little over 4 runs per game.
Reds vs White Sox Prediction
The White Sox do not need to do anything here other than starting to get warmed up for the postseason they will be appearing in. The Reds are pretty much out of playoff contention but they do have the slightest hopes still, but it starts with them winning every single game to finish the season as they cannot lose or they will eliminate themselves. Their offense has been scoring a ton of runs in their last 3 games which shows that they still have a lot of fight left in them. They will clearly keep swinging until the end so the best bet to place here is on the Reds to win as the momentum is still with them at the moment.
Reds White Sox Prediction: Our MLB Pick for Wednesday, September 29, 2021 (8:10 pm ET start time) is Reds 9 White Sox 2.
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MLB Betting Trends
Cincinnati Reds: 23-21 (+11.1 units) on the money line as a road underdog of +100 or higher. 14-11 (+4.4 units) on the money line on the road when the total is 8 to 8.5.
Chicago White Sox: 43-31 (-15.1 units) on the money line as a favorite of -150 or more. 89-68 (-8.4 units) on the money line in all games.
Cincinnati Reds: L. Castillo (SP) Prob Fri - Personal. W. Miley (SP) Out indefinitely - Neck injury. T. Naquin (CF) out for season - Ribs injury.
Chicago White Sox: A. Engel (CF) Ques Mon - Leg injury. D. Cease (SP) day-to-day - Tricep injury. B. Goodwin (CF) Out indefinitely - Back injury.
Players to Watch
Cincinnati Reds: Nick Castellanos is one player to watch here. He leads his team in batting average and in hits. His team still has the slightest chance of making it to the postseason but his team cannot lose a single game so look for him to get some hits and get on base to give his team a chance of bringing in some runs and winning some more games.
Chicago White Sox: Jose Abreu is one player to watch in this matchup. He leads his team in home runs and in RBI this season. The White Sox have already punched their ticket into the postseason so now the only thing left to do is to start getting warmed up and hitting full stride by the time the playoffs start. Look for him to keep getting hits and bringing in runs as he tries to prepare himself for a solid postseason run.
"It is tough to see anything when your overall goal is to make the postseason. Maybe when it's all over we can enjoy the winning season." - David Bell after beating the Pirates on Monday.
"It seems they have issues when someone plays aggressively but not when they pitch aggressively and beyond the limits. The game is played two ways, not just one way." - Tony La Russa on Abreu getting hit by a pitch against the Tigers.
J. India 2B
M. Schrock LF
N. Castellanos RF
J. Votto 1B
E. Suarez 3B
K. Farmer SS
D. DeShields CF
T. Barnhart C
R. Sanmartin P
Chicago White Sox
L. Robert CF
L. Garcia SS
J. Abreu 1B
Y. Grandal DH
E. Jimenez LF
Y. Moncada 3B
A. Vaughn RF
C. Hernandez 2B
Z. Collins C
Batting Average: N. Castellanos (.310)
Hits: N. Castellanos (161)
Home Runs: J. Votto (35)
RBI: N. Castellanos (97)
Stolen Bases: J. India (12)
Wins: T. Mahle (13)
Saves: M. Givens (8)
ERA: A. Warren (1.42)
Chicago White Sox
Batting Average: L. Robert (.346)
Hits: T. Anderson (153)
Home Runs: J. Abreu (29)
RBI: J. Abreu (113)
Stolen Bases: T. Anderson (18)
Wins: D. Cease (13)
Saves: L. Hendriks (37)
ERA: C. Kimbrel (2.30)
Cincinnati Reds: David Bell (3rd season)
Chicago White Sox: Tony La Russa (9th season, non-consecutive)
70degrees F sunny, 60% humidity, 0% chance of rain, up to 7 mph wind speeds W.