Cincinnati Reds vs Chicago White Sox Prediction, Preview and Odds - 09/28/2021

by Amedeus Mastrangelo

Game Time: 8:10 pm ET, Tuesday, September 28, 2021
Venue:  Guaranteed Rate Field, Chicago, IL
Where to Watch:  NBCS-CHI

 

Opening Odds at USA Sportsbooks

DraftKings:  Moneyline odds:  Reds +160, White Sox -190; Over/Under:  9 runs
Bet365:  Moneyline odds:  Reds +155, White Sox -175; Over/Under:  9 runs
BetMGM:  Moneyline odds:  Reds +155, White Sox -190; Over/Under:  9 runs
 

Season Record

Cincinnati Reds:  81-75 (3rd place, NL Central)
Chicago White Sox:  88-68 (1st place, AL Central)
 
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Cincinnati Reds vs Chicago White Sox Preview and Analysis

 
Recent Form
Cincinnati Reds:  6-4 last 10
Chicago White Sox:  5-5 last 10
 
 
 

Cincinnati Reds Analysis

The Reds are coming into this game after winning their series finale against the Washington Nationals on Sunday. They are currently on a 3 game winning streak after taking that game going on to win their four-game series against the Nats. They have a 1-off game on Monday against the Pittsburgh Pirates and then will be moving on to this game on Tuesday in the series-opener of a two-game series against the White Sox. Monday's result is still pending as they have not played that game yet. Reiver Sanmartin will be getting the nod for Monday's game while Luis Castillo will be the starting pitcher on the mound in this game on Tuesday. He is 8-16 with a 4.05 ERA this season. He was credited with the loss in his last time out and his team has lost 5 of their last 6 games when he has started. In his last start, he allowed 2 ER, 1 being a HR, and 3 BB with 6 Ks on 6 hits through 6 IP against the Nats last Thursday. This will be the first time he has faced the White Sox lineup this year as these two teams do not meet that often. Their offense has scored 26 runs in their last 4 games averaging over 6 runs scored per game in that span and they have allowed their opponents to score 18 runs against them in that same span allowing over 4 runs per game.
 

Chicago White Sox Analysis

The White Sox are coming into this game after winning their series finale against the Cleveland Indians on Sunday. They played them in a five-game series with a double-header last Thursday and they took 3 of those 5 games. They have a 1-off game against the Detroit Tigers on Monday with that result still pending as that game has not been played yet. They will move on to this game on Tuesday afterward as they will be facing the Reds in a two-game series. Dallas Keuchel will be the starter for Monday's game while Reynaldo Lopez will be throwing the first pitch for them in this game on Tuesday. He is 3-3 with a 3.16 ERA this season. He has been credited with 2 straight losses as his team has lost 2 of his last 3 starts but they have also won 4 of his last 6 starts so a bit of a mixed bag with him on the mound. In his last start, he allowed 2 ER, both of them being homers, and 0 BB with 4 strikeouts on 4 hits through 3.1 innings of work against the Indians last Thursday. These two teams do not meet very often since they are in different leagues so this will be his first time facing the Reds lineup this year. Their offense has scored 16 runs in their last 5 games averaging a little over 3 runs scored per game in that span and they have allowed their opponents to score 15 runs against them in that same span allowing 3 runs per game. 
 

 

Reds vs White Sox Prediction

The Reds are pretty much out of playoff contention as they would need to win all 6 games in the remainder of their season and even then the St. Louis Cardinals would clinch if they win just 1 more game. They cannot play spoiler here either as the White Sox have already locked up their division. Still, the value is on the Reds here as they have been playing in better form recently. The Reds are on a little win streak while the White Sox have lost a good majority of their games in the last 2 weeks. The best bet to place here is on the Reds to win this game as they will keep fighting to try and end their season on a good note at least.
 
Reds White Sox Prediction:  Our MLB Pick for Tuesday, September 28, 2021 (8:10 pm ET start time) is Reds 4 White Sox 1.
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MLB Betting Trends

 
Cincinnati Reds: 187-193 (-23.3 units) on the money line in all games. 87-102 (-7.7 units) on the money line in road games.
Chicago White Sox: 127-72 (+15.8 units) on the money line as a favorite of -110 or higher. 106-80 (+13.2 units) on the money line in home games.
 

Key Injuries

 
Cincinnati Reds:  J. Votto (1B) Ques Mon - Knee injury. W. Miley (SP) Out indefinitely - Neck injury. T. Naquin (CF) out for season - Ribs injury.
Chicago White Sox:  A. Engel (CF) Ques Mon - Leg injury. M. Wright (RP) Ques Mon - Suspension. B. Goodwin (CF) Out indefinitely - Back injury.
 

Players to Watch

 
Cincinnati Reds: Joey Votto is one player to watch in this game. He leads his team in home runs and in RBI. His team still has a very slim chance at the postseason so look for him to keep fighting and playing his best until the end of the season.
 
Chicago White Sox: Tim Anderson is one player to watch here. He leads his team in hits and in stolen bases. He will need to start heating up for the postseason so look for him to make some good hits here and start getting warmed up.
 

Notable Quotes

"All these games are important. We are focused on each day to finish strong." - David Bell on how his team is approaching these last few games.
 
"We had the high of the clinch, and yesterday we were back on our heels. We can't maintain our edge that way. Today you saw everybody out there, a lot of energy, good live actions, making plays, getting base hits. Once in a while you have a game you need to address and we addressed it really well." - Tony La Russa on his team’s attitude in the last few games of the season.
 
 
 

Starting Lineups

 
Cincinnati Reds
J. India 2B
T. Stephenson C
N. Castellanos RF
E. Suarez 3B
K. Farmer SS
A. Cabrera 1B
D. DeShields LF
J. Barrero CF
T. Mahle P
 
Chicago White Sox
T. Anderson SS
L. Garcia 2B
J. Abreu DH
Y. Grandal C
E. Jimenez LF
Y. Moncada 3B
G. Sheets 1B
A. Vaughn RF
B. Hamilton CF
 

Statistical Leaders

 
Cincinnati Reds
Batting Average:  N. Castellanos (.309)
Hits:  N. Castellanos (160)
Home Runs:  J. Votto (33)
RBI:  J. Votto (92)
Stolen Bases:  J. India (11)
Wins:  T. Mahle (13)
Saves:  M. Givens (8)
ERA:  A. Warren (1.45)
 
Chicago White Sox
Batting Average:  L. Robert (.349)
Hits:  T. Anderson (153)
Home Runs:  J. Abreu (29)
RBI:  J. Abreu (113)
Stolen Bases:  T. Anderson (18)
Wins:  D. Cease (13)
Saves:  L. Hendriks (36)
ERA:  C. Kimbrel (2.30)
 
Managers:
Cincinnati Reds: David Bell (3rd season)
Chicago White Sox: Tony La Russa (9th season, non-consecutive)
 

Weather Forecast

67 degrees F sunny, 65% humidity, 0% chance of rain, up to 6 mph wind speeds SW.


Amedeus Mastrangelo

About the Author:

Amedeus Mastrangelo has been heavily wagering on all sports for years and plays just about everything, including sides, totals, favorites, underdogs, against the spread, alternative spreads, first half, second half, player props, and futures. The bottom line is, if Mastrangelo can see an edge in any way shape or form, then he's going to take advantage.

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