Chicago White Sox vs New York Yankees Prediction, Preview and Odds - 05/21/2022

Game Time: 1:05 pm ET, Saturday, May 21, 2022

Venue:  Yankee Stadium, Bronx, NY

Where to Watch:  MLB Network

DraftKings:  Moneyline odds:  White Sox +135, Yankees -155; Over/Under:  9 runs

Bet365:  Moneyline odds:  White Sox +135, Yankees -155; Over/Under:  9 runs

BetMGM:  Moneyline odds:  White Sox +135, Yankees -155; Over/Under:  9 runs

 

Chicago White Sox:  19-19 (2nd place, AL Central)

New York Yankees:  28-10 (1st place, AL East)

 

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Chicago White Sox:  5-5 last 10

New York Yankees:  8-2 last 10

 

 

 

The White Sox are coming into this game with a 19-19 record overall and they are 10-9 in their road games this season where they will be in this game. They have lost 2 of their last 3 games but are coming into this one off of a win in their last game which snapped a 2 game losing streak that they were on. They just won their 5-game series against the Kansas City Royals 3-2 and they are playing the 2nd game of a 3-game series with the Yankees on Saturday. This will be the 2nd game of the series on Saturday with the series opener still to be played on Friday. Dallas Keuchel is the starting pitcher for them on Friday while Johnny Cueto is on the mound for them here on Saturday. He is 0-0 with a 0.00 ERA this season. His team won their only game this season with him as a starter. In his last start, he allowed 0 ER, 0 HRs, and 2 BB with 7 Ks on 2 hits in 6 IP against the Kansas City Royals. They scored 18 runs in their last series averaging just under 4 runs scored per game in that span and they allowed 15 runs against them averaging 3 runs allowed per game.

 

The Yankees are coming into this game with a 28-10 record overall and they are 14-4 in their home games this season where they will be in this game. They have won 4 of their last 5 games but are coming into this one off of a loss in their last game which snapped a 4 game winning streak that they were on. They just won their 4-game series against the Baltimore Orioles 3-1 and they are playing the 2nd game of a 3-game series with the White Sox on Saturday. This will be the 2nd game of the series on Saturday with the series opener still to be played on Friday. Nestor Cortes is the starting pitcher for them on Friday while Luis Severino will be on the mound for them here on Saturday. He is 3-0 with a 3.63 ERA this season. His team won all 7 games this season with him as a starter. In his last start, he allowed 1 earned run, 1 homer, and 2 BB with 7 strikeouts on 1 hit in 6 innings played against the Baltimore Orioles. They scored 20 runs in their last series averaging 5 runs scored per game in that span and they allowed 17 runs against them averaging just over 4 runs allowed per game.

 

The Yankees are coming into this game as a favorite with the current betting odds. The Yankees have been heating up over the last few weeks and have been winning a lot of their games, currently with the best record in the MLB. They just won 3 of their 4 games against the White Sox last week and that series was in Chicago. The Yankees will be at home this time and they have not been slowing down in their games yet. They have Severino on the mound here and they have had a lot of success with him starting this season as they have not lost a game with him yet. The White Sox have Cueto starting here and he pitched well in his last start that was his only start this season and he went up against the Royals who do not have that great of a lineup. This will be the first real test for Cueto this season but the White Sox still have an awful bullpen that the Yankees beat up last week so even if he leaves this game tied or with a lead, the Yankees could easily come back at home to win it. The best bet here is on the Yankees to win.

 

White Sox Yankees Prediction:  Our MLB Pick for Saturday, May 21, 2022 (1:05 pm ET start time) is Yankees 7 White Sox 4.

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Chicago White Sox: 22-46 (-19.5 Units) ML as an underdog of +100 or higher. 68-67 (-8.8 Units) ML in road games. 25-18 UNDER as a road underdog of +100 or higher.

New York Yankees: 157-111 (-8.6 Units) ML in all games. 132-92 (-18.6 Units) ML as a favorite of -110 or higher. 21-14 UNDER as a favorite of -110 or higher.

 

 

Chicago White Sox:  Y. Moncada (3B) Ques Fri - Leg. L. Lynn (SP) Early June - Knee. M. Kopech (RP) Out indefinitely - Personal.

New York Yankees:  C. Green (RP) Ques Fri - Forearm. B. Rortvedt (C) Mid July - Oblique. D. German (SP) Mid June - Shoulder.

 

 

 

"I was just trying to get a run in and get that egg off the board. I was being myself, playing my game, and having fun while doing it. Just putting us in the best position to be successful." - Tim Anderson after their win against the Royals on Thursday.

 

 

"Any time you go out on the road and throw a 6-2 out there, you'll take that. Look forward to being back at Yankee Stadium." - Aaron Boone after his team’s loss against the Orioles on Thursday.

 

 

 

Tim Anderson (R) SS

Yoan Moncada (S) 3B

Luis Robert (R) CF

Jose Abreu (R) DH

AJ Pollock (R) LF

Gavin Sheets (L) 1B

Andrew Vaughn (R) RF

Reese McGuire (L) C

Josh Harrison (R) 2B

 

DJ LeMahieu (R) 3B

Aaron Judge (R) RF

Anthony Rizzo (L) 1B

Giancarlo Stanton (R) DH

Gleyber Torres (R) 2B

Aaron Hicks (S) CF

Isiah Kiner-Falefa (R) SS

Kyle Higashioka (R) C

Marwin Gonzalez (S) LF

 

 

Batting Average:  Tim Anderson (.346)

Hits:  Tim Anderson (47)

Home Runs:  Luis Robert (6)

RBI:  Luis Robert (17)

Stolen Bases:  Tim Anderson (7)

Wins:  Reynaldo Lopez (4)

Saves:  Liam Hendriks (12)

ERA:  Johnny Cueto (0.00)

 

Batting Average:  Miguel Andujar (.400)

Hits:  Aaron Judge (42)

Home Runs:  Aaron Judge (14)

RBI:  Giancarlo Stanton (35)

Stolen Bases:  Aaron Hicks (5)

Wins:  Clay Holmes (4)

Saves:  Aroldis Chapman (9)

ERA:  JP Sears (0.00)

 

Managers:

Chicago White Sox: Tony La Russa (2nd season)

New York Yankees: Aaron Boone (5th season)