by Rod Pearson
Thursday, Nov 27, 2025
Game Time: 7:30 pm ET, Saturday, November 29, 2025
Venue: Yulman Stadium, New Orleans, LA
Where to Watch: ESPNU
Opening Odds at USA Sportsbooks
DraftKings: Point Spread: Charlotte +29.5, Tulane -29.5; Over/Under: 52.5 points
Bet365: Point Spread: Charlotte +30, Tulane -30; Over/Under: 53 points
BetMGM: Point Spread: Charlotte +29.5, Tulane -29.5; Over/Under: 53.5 points
Season Record
Charlotte 49ers: 1-10 (0-7) (14th place, American)
Tulane Green Wave: 9-2 (6-1) (2nd place, American)
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Recent Form
Charlotte 49ers: lost their last game on the road against the Georgia Bulldogs 35-3.
Tulane Green Wave: won their last game on the road against the Temple Owls 37-13.
Charlotte 49ers vs Tulane Green Wave Preview and Analysis
Charlotte is entering this game with a 1-10 record overall and they have a 0-7 record in their conference games too. They are 1-5 in their home games, 0-4 in their road games, and they are also 0-1 in their neutral site games this season, but they will be on the road for this game. They lost their last game against Georgia 35-3. Grayson Loftis was the starting QB and he completed 14/27 passes for 130 passing yards, 0 touchdowns, and 2 interceptions. Jariel Cobb led the team in rushing yards with 26. E. Jai Mason led the receivers with 38 receiving yards on 1 reception. Reid Williford and Gavin Willis each led the defense in that game with 6 solo tackles and 1 assisted tackle while Curtis Simpson and Yamil Talib each led the defense in sacks with 1. Ja'Qurious Conley came away with the only interception for them in that one.
Tulane is entering this game with a 9-2 record overall and they have a 6-1 record in their conference games too. They are 5-0 in their home games, 4-2 in their road games, and they are also 0-0 in their neutral site games this season, but they will be at home for this game. They won their last game against Temple 37-13. Jake Retzlaff was the starting QB and he completed 17/28 passes for 231 passing yards, 2 touchdowns, and 0 interceptions. Jamauri McClure led the team in rushing yards with 122. Shazz Preston led the receivers with 96 receiving yards on 5 receptions and 1 TD. Chris Rodgers led the defense in that game with 5 solo tackles and 3 assisted tackles while Jordan Norman led the defense in sacks with 2. No one on the defense came away with an interception for them in that one.
Charlotte vs Tulane Prediction
The current betting odds have Tulane listed as a 29.5 point favorite in this game according to Draftkings Sportsbook. Tulane has looked really good in their games this season with their 9-2 record overall and their 6-1 conference record which has them right near the top of the American Conference. They have also looked great on their home field this year with their 5-0 home record. Meanwhile, Charlotte has looked terrible in their games this season with their 1-10 record overall and their 0-7 conference record which has them right at the bottom of the American Conference. They have been a terrible road team too with their 0-4 road record this year. They are off a 35-3 loss to Georgia in their last one and they weren't competitive in that game. They have been the worst team in the conference all season and they have been getting blown out in a lot of their games too. They have nothing left to play for either and their offense hasn't been putting up a lot of points this year either. Tulane is off a 37-13 win over Temple in their last one and they are starting to roll now as they have their sights set on the American Championship. They are currently ranked inside the top 25 too and have the inside track on the group of 5 playoff spot. Tulane is going to continue rolling here as they still have a lot to play for and can use this game as a tune up before the conference championship. The best way to place a bet here is on Tulane to cover the spread in this game.
Charlotte Tulane Prediction: Our NCAAF Pick for Saturday, November 29, 2025 (7:30 pm ET start time) is Tulane 49 Charlotte 10.
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NCAAF Betting Trends
Charlotte 49ers: 11-3 ATS as a road underdog. 6-2 ATS in a road game where the total is between 49.5 and 56. 8-1 ATS on the road after a loss by 17 or more points. 10-3 OVER when the total is between 49.5 and 56. 12-6 OVER after a loss by 17 or more points.
Tulane Green Wave: 3-6 ATS off a road win against a conference rival. 1-4 ATS versus poor rushing teams - averaging 120 rushing yards/game or less. 1-4 ATS at home vs. bad defensive teams who give up 31 or more points/game. 7-4 OVER versus poor rushing teams - averaging 3.25 rushing yards/carry or less.
Key Injuries
Charlotte 49ers: D. Wallace (DL) Questionable - Undisclosed. M. Williams (DL) Questionable - Undisclosed. J. King (OG) Questionable - Undisclosed. J. Johnson (DL) Questionable - Undisclosed. D. Edwards (CB) Questionable - Undisclosed. B. Brinkley (OG) Questionable - Undisclosed. M. Bowers (OG) Questionable - Undisclosed. P. Startz (LB) Questionable - Undisclosed. G. Laskey (TE) Out - Undisclosed. I. Bullerdick (OG) Out - Undisclosed. U. Rockhead (OG) Out - Undisclosed. O. Davis (OG) Out - Undisclosed. A. Tifase (DL) Out - Undisclosed. D. Kelley (OG) Out - Undisclosed. A. Adair (OG) Out - Undisclosed. J. Olson (WR) Out - Undisclosed. H. Rutledge (RB) Out - Undisclosed. C. Harrell (QB) Out - Knee. D. Burgess (DL) Out - Upper Body. J. McGowan (WR) Out - Lower Body.
Tulane Green Wave: C. Helmke (K) Questionable - Undisclosed. B. Bohanon (WR) Questionable - Lower Body. J. Lewis (CB) Questionable - Undisclosed. J. Hollifield (OG) Questionable - Undisclosed. J. Tchienchou (S) Questionable - Undisclosed. G. Henderson (DL) Out - Undisclosed. L. Husbands (TE) Out - Undisclosed. D. Jackson (CB) Questionable - Undisclosed. H. Lawson (LB) Questionable - Undisclosed. C. Klein (S) Questionable - Undisclosed. T. Thompson (TE) Out - Knee. D. Agu (LB) Out - Undisclosed.
Notable Quotes
“We’re doing our best to lay a foundation, it's very difficult with the scoreboard this year.” - Tim Albin after his team’s loss against UGA in their last game.
“I think we might be like the 75th best team in the country. I don’t think we’re bottom 25. But I don’t think we’re Top 25, either. We have some work to do.” - Jon Sumrall after his team’s win against Temple in their last game.
Starting Lineups
Charlotte 49ers
WR Brown, Sean
WR Mason, E. Jai
WR Nicholas, Javen
TE McGee, Gus
QB Loftis, Grayson
RB Gainey Jr., Rod
Tulane Green Wave
WR Preston, Shazz
WR Brown-Stephens, Anthony
WR Bohanon, Bryce
TE Pascuzzi, Johnny
QB Retzlaff, Jake
RB Gordon, Javin
Statistical Leaders
Charlotte 49ers
Passing: Grayson Loftis (1,275)
Rushing: Rod Gainey Jr. (256)
Receiving: Javen Nicholas (700)
Touchdowns: Javen Nicholas (5)
Tulane Green Wave
Passing: Jake Retzlaff (2,426)
Rushing: Jake Retzlaff (565)
Receiving: Shazz Preston (539)
Touchdowns: Jake Retzlaff (12)
Coaches:
Charlotte 49ers: Tim Albin (1st season)
Tulane Green Wave: Jon Sumrall (2nd season)
Rod Pearson
About the Author:
Rod Pearson has been a rabid sports fan his entire life. He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years. In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective. Join Rod every day as he breaks down the games to find the best betting value.
