Carolina Panthers vs Atlanta Falcons Prediction, Preview and Odds - 11/16/2025

by Rod Pearson

Thursday, Nov 13, 2025
 
Game Time: 1:00 pm ET, Sunday, November 16, 2025
Venue:  Mercedes-Benz Stadium, Atlanta, GA
Where to Watch:  FOX


Opening Odds at USA Sportsbooks

DraftKings:  Point Spread:  Panthers +3.5, Falcons -3.5; Over/Under:  42.5 points
Bet365:  Point Spread:  Panthers +3.5, Falcons -3.5; Over/Under:  42.5 points
BetMGM:  Point Spread:  Panthers +3.5, Falcons -3.5; Over/Under:  42.5 points

Season Record

Carolina Panthers:  5-5 (2nd place, NFC South)
Atlanta Falcons:  3-6 (3rd place, NFC South)

Do not miss out on our expert handicapper analysis! Kyle Hunter is on a HOT STREAK in the NFL on a 10-3 NFL RUN for +$6,730 PROFIT! Make sure you check out his picks and many more from the expert handicappers featured in the Shop Picks section.

Recent Form
Carolina Panthers:  lost their last game at home against the New Orleans Saints 17-7.
Atlanta Falcons:  lost their last game at a neutral site against the Indianapolis Colts 31-25 in overtime.


Carolina Panthers vs Atlanta Falcons Preview and Analysis


The Panthers are entering this game with a 5-5 record overall and they have a 1-1 record in their divisional games too. They are 3-2 in their home games, 2-3 in their road games, and they are also 0-0 in their neutral site games this season, but they will be on the road for this game. They lost their last game against the New Orleans Saints 17-7. Bryce Young was the starting QB and he completed 17/25 passes for 124 passing yards, 0 touchdowns, and 1 interception. Rico Dowdle led the team in rushing yards with 53 and 1 TD. Tetairoa McMillan led the receivers with 60 receiving yards on 5 receptions. Tre'von Moehrig led the defense in that game with 6 solo tackles and 1 assisted tackle while Trevin Wallace and Nic Scourton each led the defense in sacks with 1. No one on the defense came away with an interception for them in that one.
 
 
 
The Falcons are entering this game with a 3-6 record overall and they have a 0-2 record in their divisional games too. They are 2-2 in their home games, 1-3 in their road games, and they are also 0-1 in their neutral site games this season, but they will be at home for this game. They lost their last game against the Indianapolis Colts 31-25 in OT. Michael Penix Jr. was the starting QB and he completed 12/28 passes for 177 passing yards, 1 touchdown, and 0 interceptions. Bijan Robinson led the team in rushing yards with 84. Drake London led the receivers with 104 receiving yards on 6 receptions and 1 TD. Xavier Watts led the defense in that game with 6 solo tackles and 5 assisted tackles while Ronnie Harrison Jr., Jalon Walker, Arnold Ebiketie, James Pearce Jr., Kaden Elliss, Brandon Dorlus, and Zach Harrison each led the defense in sacks with 1. Jessie Bates III came away with the only interception for them in that one.


Panthers vs Falcons Prediction

The current betting odds have the Falcons listed as a 3.5 point favorite in this game according to Draftkings Sportsbook. The Falcons haven't looked good in their games this season with their 3-6 record overall which has them right near the bottom of the NFC South. They have looked terrible lately as they are on a losing streak and coming off a 31-25 loss to the Colts in Germany, but they have looked better in their last 2 losses and they are going to be desperate for a win after coming so close the last 2 games. Meanwhile, the Panthers haven't looked bad in their games this season with their 5-5 record overall which has them right near the top of the NFC South. They have looked really good lately as they find ways to win games, but they have also been beating up on a lot of bad opponents. Now they are on the road where they haven't looked as good this season, going 2-3 in road games, and they are off a terrible 17-7 loss at home to the Saints in their last one. The Falcons still have a lot more talent on their team than the Panthers do and the Falcons are a lot better than their record suggests. The Panthers find ways to win games, but their offense hasn't really looked that great with Bryce Young not being asked to do much. The Falcons are going to be desperate for a bounce back win in this one and this is a big game for them to get back in the division. The best way to place a bet here is on the Falcons to cover the spread in this game. 

Panthers Falcons Prediction:  Our NFL Pick for Sunday, November 16, 2025 (1:00 pm ET start time) is Falcons 24 Panthers 17.
Don't miss our champion handicappers free picks and expert football picks today. And if you enjoyed this Carolina Panthers Atlanta Falcons prediction, be sure to drop by every day for our weekly NFL predictions and previews.

NFL Betting Trends


Carolina Panthers: 42-28 ATS on the road after scoring 14 points or less last game. 31-23 ATS on the road when playing against a bad team (Win Pct. 25% to 40%). 25-17 ATS on the road versus poor rushing defenses - allowing >=130 rushing yards/game or more. 16-8 OVER in all games where the total is between 42.5 and 49 points.

Atlanta Falcons: 15-26 ATS in all games. 5-10 ATS as a home favorite of 7 points or less. 3-7 ATS after a loss by 6 or less points. 7-2 OVER after allowing 30 points or more last game. 9-4 OVER versus good rushing teams - averaging 4.5 rushing yards/carry or more.

Key Injuries


Carolina Panthers:  D. Brown (DL) Injured - Knee. R. Dowdle (RB) Injured - Quadriceps. B. Tremayne (WR) Injured - Hip. C. Zavala (OG) Injured - Elbow. T. Wallace (LB) Injured - Shoulder. L. Ransom (S) Injured - Hand.

Atlanta Falcons:  J. Agnew (WR) Injured - Foot. J. Matthews (OT) Injured - NIR - Rest. L. Floyd (DL) Injured - Hamstring. J. Woods (LB) Injured - Hamstring. M. Hughes (CB) Injured - Neck. C. Lindstrom (OG) Injured - Foot. L. McCullough (LS) Injured - NIR - Personal. D. Malone (DL) Injured - Ankle. M. Bergeron (OG) Injured - Ankle. Z. Harrison (DL) Injured - Knee. D. London (WR) Injured - Illness. L. London (DL) Injured - Shoulder. D. Alford (CB) Injured - Concussion. S. Roberts (DL) Injured - Knee. B. Dorlus (DL) Injured - Oblique. M. Verdon (LB) Injured - Shoulder.

Notable Quotes


“We didn’t play our version of football. That was not us. We can’t have that. We can’t give up big plays and we can’t turn the ball over. Our offense has to be more opportunistic and take advantage of some of the situations where the defense made some stops for us and got us the ball back.” - Dave Canales after his team’s loss against the Saints in their last game. 


“We had plenty of opportunities to win it. We’ve just got to find a way to get better, whether it’s stopping the run, whether it’s covering kicks better, returning the ball better or converting on third down — all the things that kind of hurt us today." - Raheem Morris after his team’s loss against the Colts in their last game. 


Starting Lineups


Carolina Panthers
WR McMillan, Tetairoa
WR Legette, Xavier
WR Coker, Jalen
TE Sanders, Ja'Tavion
QB Young, Bryce
RB Dowdle, Rico 

Atlanta Falcons
WR Mooney, Darnell 
WR London, Drake
WR Sills V, David
TE Pitts Sr., Kyle
QB Penix Jr., Michael
RB Robinson, Bijan

Statistical Leaders


Carolina Panthers
Passing: Bryce Young (1,514)
Rushing: Rico Dowdle (788)
Receiving: Tetairoa McMillan (618)
Touchdowns: Rico Dowdle (6)

Atlanta Falcons
Passing: Michael Penix Jr. (1,807)
Rushing: Bijan Robinson (679)
Receiving: Drake London (691)
Touchdowns: Drake London (6)

Coaches:
Carolina Panthers: Dave Canales (2nd season)
Atlanta Falcons: Raheem Morris (2nd season)

 

Rod Pearson

About the Author:

Rod Pearson has been a rabid sports fan his entire life.  He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years.  In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective.  Join Rod every day as he breaks down the games to find the best betting value.

All photographic images used for editorial content have been licensed from the Associated Press.

© 2025 Al McMordie's BigAl.com. All Rights Reserved.