Buffalo Bills vs Miami Dolphins Prediction, Preview and Odds - 09/25/2022

by Rod Pearson

Game Time: 1:00 pm ET, Sunday, September 25, 2022
Venue:  Hard Rock Stadium, Miami Gardens, FL
Where to Watch:  CBS

 

Opening Odds at USA Sportsbooks

DraftKings:  Point Spread:  Bills -5.5, Dolphins +5.5; Over/Under:  53.5 points
Bet365:  Point Spread:  Bills -5.5, Dolphins +5.5; Over/Under:  54 points
BetMGM:  Point Spread:  Bills -5.5, Dolphins +5.5; Over/Under:  54 points
 

Season Record

Buffalo Bills:  2-0 (2nd place, AFC East)
Miami Dolphins:  2-0 (1st place, AFC East)
 
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Recent Form
Buffalo Bills:  won their last game at home against the Tennessee Titans 41-7.
Miami Dolphins:  won their last game on the road against the Baltimore Ravens 42-38.

 

Buffalo Bills vs Miami Dolphins Preview and Analysis

 
The Bills are entering this game with a 2-0 record overall and they are playing their 2nd road game of the season here as they are 1-0 in their road games. Their offense is averaging 413.5 YPG and 36 PPG while their defense is allowing 215 YPG and 8.5 PPG against them. They won their last game at home against the Tennessee Titans 41-7 and are now playing their 1st divisional game of the season. Josh Allen was the starting quarterback in that game and he completed 26/38 passes for 317 yards and 4 touchdowns. James Cook led the team in rushing with 53 yards on 11 rushing attempts. Stefon Diggs led the team in receiving with 148 yards and 3 TDs on 12 receptions. Taron Johnson led the defense in that game with 4 solo tackles and 0 assisted tackles. Gregory Rousseau and Tremaine Edmunds all led the defense in sacks with 1 each while Jordan Poyer and Matt Milano each came away with 1 interception for them in that one.
 
 
 
The Dolphins are entering this game with a 2-0 record overall and they are playing their 2nd home game of the season here as they are 1-0 in their home games this year. Their offense is averaging 427 YPG and 31 PPG while their defense is allowing 372 YPG and 22.5 PPG against them. They won their last game on the road against the Baltimore Ravens 42-38 and they are now playing their 2nd division game of the year as they are already 1-0 in the AFC East. Tua Tagovailoa was the starting QB in that game and he completed 36/50 passes for 469 yards, 6 touchdowns, and 2 interceptions. Raheem Mostert led the team in rushing with 51 yards on 11 carries. Tyreek Hill led the team in receiving with 190 yards and 2 TDs on 11 catches while Jaylen Waddle had 171 receiving yards and 2 Tds on 11 receptions. Christian Wilkins led the defense in that game with 6 solo tackles and 2 assisted tackles. No one on the defense recorded a sack for them or came away with an interception in that one.
 

 

Bills vs Dolphins Prediction

The current betting odds have the Bills listed as a 5.5 point favorite in this game according to Draftkings Sportsbook. The Bills are 2-0 this year but they have completely dismantled both teams they have played against. They won against the defending Super Bowl champs in LA on opening night and the score wasn't even close. They followed up with another embarrassing win over the Titans on Monday night and now play their 1st divisional game of the year here. The Dolphins are already 1-0 in the division with a leg up as they played the patriots in Week 1, getting a win there, and now they had a huge comeback last week in Baltimore as they were trailing by 21 points to the Ravens and scored 28 points in the 4th quarter alone to win that one. That was a very big comeback and emotional game for them but they are going to be due for a let down here. They have the best team in the NFl rolling into Miami here and the Bills look unstoppable as their offense just doesn't stop scoring and their defense doesn't even allow many points. They are determined to win the Super Bowl this year after the way things ended for them last year in the playoffs, and they are not going to let the shiny new Dolphins outshine them in the division and in this game. The best way to place a bet here is on the Dolphins to cover the spread in this game.
 
Bills Dolphins Prediction:  Our NFL Pick for Sunday, September 25, 2022 (1:00 pm ET start time) is Bills 42 Dolphins 24.
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NFL Betting Trends

 
Buffalo Bills: 10-18 ATS after scoring 40 points or more last game. 23-15 OVER in all games. 11-5 OVER in road games.
Miami Dolphins: 22-13 ATS in all games. 13-5 ATS in home games. 17-10 OVER after gaining 350 or more passing yards in the last game.
 

Key Injuries

 
Buffalo Bills:  T. White (CB) Out indefinitely - Knee. E. Oliver (DT) day-to-day - Ankle. M. Hyde (S) day-to-day - Neck.
Miami Dolphins:  J. Lovett (FB) I-R - Undisclosed. A. Shaheen (TE) I-R - Knee. T. Williams (CB) I-R - Knee.
 

Notable Quotes

 
"When we execute how we know we're supposed to execute, success typically leads to success. We're just trying to be the best version of ourselves." - Josh Allen after their win against the Titans in their last game.
 
 
"I think it was a moment he'll never forget and can use it moving forward. I couldn't be happier for him. His teammates learned a lot about him, and I think he learned something about himself." - Mike McDaniel after his team’s win against the Ravens in their last game.
 
 

Starting Lineups

 
Buffalo Bills
WR Davis, Gabe
WR Diggs, Stefon
WR McKenzie, Isaiah 
TE Knox, Dawson
QB Allen, Josh 
RB Singletary, Devin
FB Gilliam, Reggie 
 
Miami Dolphins
WR Waddle, Jaylen
WR Hill, Tyreek
WR Wilson Jr., Cedrick 
TE Smythe, Durham 
QB Tagovailoa, Tua
RB Edmonds, Chase
FB Ingold, Alec 
 

Statistical Leaders

 
Buffalo Bills
Passing: J. Allen (614)
Rushing: D. Singletary (67)
Receiving: S. Diggs (270)
Touchdowns: S. Diggs (4)
 
Miami Dolphins
Passing: T. Tagovailoa (739)
Rushing: R. Mostert (67)
Receiving: T. Hill (284)
Touchdowns: J. Waddle (3)
 
Coaches:
Buffalo Bills: Sean McDermott (6th season)
Miami Dolphins: Mike McDaniel (1st season)


Rod Pearson

About the Author:

Rod Pearson has been a rabid sports fan his entire life.  He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years.  In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective.  Join Rod every day as he breaks down the games to find the best betting value.

All photographic images used for editorial content have been licensed from the Associated Press.

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