Boston Celtics vs Denver Nuggets Prediction, Preview and Odds - 02/25/2026

Game Time: 10:00 pm ET, Wednesday, February 25, 2026

Venue:  Ball Arena, Denver, CO

Where to Watch:  ESPN

DraftKings:  Point Spread:  Celtics +3.5, Nuggets -3.5; Over/Under:  228.5 points

Bet365:  Point Spread:  Celtics +3.5, Nuggets -3.5; Over/Under:  228.5 points

BetMGM:  Point Spread:  Celtics +3.5, Nuggets -3.5; Over/Under:  228.5 points

Boston Celtics:  37-19 (1st place, Atlantic Division)

Denver Nuggets:  36-22 (2nd place, Northwest Division)

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Boston Celtics:  8-2 last 10

Denver Nuggets:  4-6 last 10

The Celtics are entering this game with a 37-19 record overall this season and they are 19-10 in their road games this season where they will be in this game. They are entering this game on a 3 game winning streak with wins coming against the Chicago Bulls, the Golden State Warriors, and the Los Angeles Lakers, but this is also the 2nd game of a back-to-back for them with their game against the Phoenix Suns still to be played on Tuesday night. In their game against the LA Lakers, Jaylen Brown led the team in points in that game with 32 while Payton Pritchard was next on the team with 30 points. Jaylen Brown led the team in assists in that game with 3 while Neemias Queta led the team in rebounds with 12. They were 48.2% from the field, 38.9% from 3-point range, and 81% from the free throw line with their shots in that game. Their offense is averaging 115.3 PPG and their defense is allowing their opponents to average 108 PPG against them. The Celtics have an ATS record of 32-24 this season and their O/U record is 21-35.

The Nuggets are entering this game with a 36-22 record overall this season and they are 15-11 in their home games this season where they will be in this game. They are entering this game off a loss against the Golden State Warriors. Nikola Jokić led the team in points in that game with 35 while Jamal Murray was next on the team with 21 points. Nikola Jokić led the team in assists in that game with 12 while Nikola Jokić led the team in rebounds with 20. They were 46.2% from the field, 25.8% from 3-point range, and 86.2% from the free throw line with their shots in that game. Their offense is averaging 120.8 PPG and their defense is allowing their opponents to average 116.3 PPG against them. The Nuggets have an ATS record of 32-26 this season and their O/U record is 37-21.

The current betting odds have the Nuggets listed as a 3.5 point favorite in this game according to Draftkings Sportsbook. The Nuggets have looked really good in their games this season with their 36-22 record overall which has them in the top half of the West. They have looked good on their home court too with their 15-11 home record this season. Meanwhile, the Celtics have looked really good in their games this season with their 37-19 record overall which has them right near the top of the East. They have been a great road team too with their 19-10 road record this year. The Celtics are off a road win over the Lakers and they have been rolling in their games lately. They are 8-2 in their last 10 games and have some momentum on their side now with 3 wins in a row. They have been one of the best teams in the East this season and have really hit the jets over the last 2 months, but they aren't in a great situation for this game now. They are playing this game on a back-to-back and they have a tough road game against the Suns the night before. They have been rolling out of the All-Star Break and have been crushing opponents on the road, but that streak isn't going to last forever and the Nuggets have the talent to stop them in their tracks here. The Nuggets haven't been at their best lately as they are 4-6 in their last 10 games and they haven't looked great coming out of the break either. They are off a bad road loss to the Warriors in their last one too, but they will be looking to bounce back in a big way here and they are going to bring their best effort at home for one of the best teams in the East right now. The Nuggets are in desperate need of a get right game and this is a great opportunity for them to take advantage of a Celtics team on the road on a back-to-back here. The best way to place a bet here is on the Nuggets to cover the spread in this game. 

Celtics Nuggets Prediction:  Our NBA Pick for Wednesday, February 25, 2026 (10:00 pm ET start time) is Nuggets 124 Celtics 117.

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Boston Celtics: 31-14 ATS revenging a same season loss vs opponent. 10-5 ATS as an underdog. 19-10 ATS in road games. 12-6 UNDER as a road underdog of 6 points or less. 31-21 UNDER when playing against a good team (Win Pct. 60% to 70%).

Denver Nuggets: 15-22 ATS as a home favorite of 6 points or less. 18-25 ATS in a home game where the total is 220 to 229.5. 22-29 ATS when playing against a good team (Win Pct. 60% to 70%). 29-22 UNDER when playing against a good team (Win Pct. 60% to 70%).

Boston Celtics:  J. Brown (SF) Day To Day - Knee. J. Tatum (PF) Out - Achilles.

Denver Nuggets:  J. Pickett (SG) Day To Day - Knee. P. Watson (SF) Out - Hamstring. A. Gordon (PF) Out - Hamstring. T. Bates (SG) Out - Foot.

"The gift that Vooch has is versatility. So it's not about what he's best at; he's good at a lot of things. And so it's an understanding of how can we take advantage of that within a game." - Joe Mazzulla after his team’s win against the LA Lakers in their game on Sunday.

“Yeah, we didn't take care of the ball. I thought we had some empty possessions that even though they weren't turnovers, they led to poor shots and run outs for them. So really poor execution throughout the start of the fourth, but the bottom line is this game came down to the start of the game." - David Adelman after his team’s loss against the Warriors in their game on Sunday.

PG Derrick White 

SG Baylor Scheierman

SF Hugo Gonzalez

PF Sam Hauser

C Neemias Queta

PG Jamal Murray

SG Christian Braun

SF Julian Strawther

PF Cameron Johnson

C Nikola Jokic

PPG: Jaylen Brown (29.2)

APG: Derrick White (5.7)

Reb/G: Nikola Vucevic (8.4)

PPG: Nikola Jokic (28.8)

APG: Nikola Jokic (10.5)

Reb/G: Nikola Jokic (12.5)

Coaches:

Boston Celtics: Joe Mazzulla (4th season)

Denver Nuggets: David Adelman (2nd season)