Big Al's Daily Angle: NFL and MLB Previews and Odds - 09/25/2022

by Big Al Staff

Sunday, Sep 25, 2022
The Sunday sports card features action in the NFL and MLB.

The second week in the National Football League continues with 14 games. Nine games kick off at 1 PM ET. The New Orleans Saints travel to Carolina to play the Panthers as a 2.5-point road favorite with the total set at 41 (all odds from DraftKings). The Chicago Bears play at home against the Houston Texans as a 3-point favorite with an over/under of 39. The Kansas City Chiefs are at Indianapolis against the Colts as a 5.5-point road favorite with a total of 50.5. The Buffalo Bills play in Miami against the Dolphins as a 4.5-point road favorite with an over/under of 53.5. The Minnesota Vikings host the Detroit Lions as a 6-point favorite with a total of 52.5. The Baltimore Ravens visit New England to play the Patriots as a 2.5-point road favorite with an over/under of 44. The Cincinnati Bengals are in New York against the Jets as a 6-point road favorite with a total of 45. The Las Vegas Raiders play at Tennessee against the Titans as a 2-point road favorite with an over/under of 45.5. Philadelphia is at Washington as a 6.5-point road favorite with a total of 47.5. 

The Los Angeles Chargers host the Jacksonville Jaguars at 4:05 PM ET as a 3-point favorite with an over/under of 42.5. Three more NFL games kick off at 4:25 PM ET. The Los Angeles Rams visit Arizona to play the Rams as a 3.5-point road favorite with a total of 48.5. The Seattle Seahawks play at home against the Atlanta Falcons as a 1-point favorite with an over/under of 42. The Tampa Bay Buccaneers are at home against the Green Bay Packers as a 1.5-point favorite with a total of 42. 

The San Francisco 49ers travel to Denver to play the Broncos on NBC and Peacock at 8:20 PM ET for Sunday Night Football. The 49ers are a 1.5-point road favorite with an over/under of 44.5. 

Major League Baseball has 15 games on its schedule. Two MLB games throw out the first pitch at 1:05 PM ET. The Houston Astros play at Baltimore against the Orioles as a -165 money line road favorite with a total of 7.5. The Atlanta Braves are at Philadelphia against the Phillies as a -125 money line road favorite with an over/under of 8.5. The Tampa Bay Rays play at home against the Toronto Blue Jays at 1:10 PM ET as a -140 money line favorite with a total of 6.5. The Chicago Cubs visit the Pittsburgh Pirates at 1:35 PM ET with both teams priced at -110 with an over/under of 8. 

Two MLB games start at 1:40 PM ET. The Miami Marlins host the Washington Nationals as a -175 money line favorite with a total of 7.5. The Milwaukee Brewers are at Cincinnati against the Reds as a -145 money line road favorite with an over/under of 8. Three more MLB games begin at 2:10 PM ET. The Chicago White Sox play at home against the Detroit Tigers as a -250 money line favorite with a total of 7.5. The Minnesota Twins are at home against the Los Angeles Angels as a -115 money line favorite with an over/under of 8. The Seattle Mariners travel to Kansas City to play the Royals as a -180 money line road favorite with a total of 7.5. 

The Cleveland Guardians play at Texas against the Rangers at 2:35 PM ET as a -135 money line road favorite with an over/under of 8. The San Diego Padres are at Colorado against the Rockies at 3:10 PM ET as a -150 money line road favorite with a total of 11. The San Francisco Giants visit Arizona to play the Diamondbacks at 3:40 PM ET. The New York Mets play at Oakland against the A’s at 4:07 PM ET as a -315 money line road favorite with an over/under of 7. The Los Angeles Dodgers are at home against the St. Louis Cardinals at 4:10 PM ET as a -150 money line favorite with a total of 9. 

The New York Yankees host the Boston Red Sox on ESPN at 7:08 PM ET for Sunday Night Baseball. The Yankees are a -175 money line favorite with an over/under of 8.5.

All photographic images used for editorial content have been licensed from the Associated Press.

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