Big Al's Daily Angle: MLB Previews and Odds - 09/21/2022

by Big Al Staff

The Wednesday sports card features action in MLB.

Major League Baseball has 15 games on its schedule. The Washington Nationals visit Atlanta to play the Braves at 12:20 PM ET. Paulo Espino takes the ball for the Nationals to pitch against the Braves Bryce Elder. The New York Mets play at Milwaukee against the Brewers at 2:10 PM ET. The Mets turn to Taijuan Walker to pitch against the Brewers’ Adrian Houser. New York is a -130 money line road favorite with an over/under of 8.5 (all odds from DraftKings).

Three MLB games throw out the first pitch at 6:40 PM ET. Miami hosts Chicago with Jesus Luzardo pitching for the Marlins against Drew Smyly for the Cubs. The Marlins are a -120 money line favorite with a total of 6.5. Boston is at Cincinnati with the Red Sox tapping Connor Seabold to battle against the Reds’ Chase Anderson. The Red Sox are a -170 money line road favorite with an over/under of 9.5. Houston travels to Tampa Bay with Lance McCullers pitching for the Astros against Corey Kluber for the Rays. The Astros are a -130 money line road favorite with a total of 7. The Philadelphia Phillies play at home against the Toronto Blue Jays at 6:45 PM ET. The Phillies send Zack Wheeler to the mound to pitch against the Blue Jays Kevin Gausman. Philadelphia is a -115 money line favorite with an over/under of 8. 

Two MLB games start at 7:05 PM ET. New York plays at home against Pittsburgh with Luis Severino pitching for the Yankees against Roansey Contreras. The Yankees are a -300 money line favorite with a total of 8. Baltimore is at home against Detroit, with the Orioles tapping Jordan Lyles to pitch against the Tigers’ Matt Manning. The Orioles are a -170 money line favorite with an over/under of 8. The Texas Rangers host the Los Angeles Angels at 8:05 PM ET. Dane Dunning takes the hill for the Rangers to battle against Patrick Sandoval for the Angels. Texas is a -145 money line favorite with a total of 8.5. 

Two MLB games begin at 8:10 PM ET. Minnesota plays at Kansas City, with the Twins turning to Bailey Ober to pitch against the Royals’ Daniel Lynch. The Twins is a -140 money line road favorite with an over/under of 8.5. Chicago is at home against Cleveland, with Lance Lynn pitching for the White Sox against Triston McKenzie for the Guardians. The White Sox are a -125 money line favorite with a total of 7.5. The San Francisco Giants travel to Colorado to play the Rockies at 8:40 PM ET. Logan Webb takes the ball for the Giants to pitch against German Marquez for the Rockies. San Francisco is a -135 money line road favorite with an over/under of 10.

Two MLB games start at 9:40 PM ET. San Diego hosts St. Louis, with the Padres tapping Blake Snell to pitch against the Cardinals’ Miles Mikolas. San Diego is a -125 money line favorite with a total of 7.5. Seattle plays at Oakland with Robbie Ray pitching for the Mariners to duel against James Kaprielian for the A’s. The Mariners are a -210 money line road favorite with an over/under of 7. The Los Angeles Dodgers play at home against the Arizona Diamondbacks at 10:10 PM ET. The Dodgers send out Dustin May to pitch against the Diamondbacks’ Madison Bumgarner. Los Angeles is a -295 money line favorite with a total of 8.5. 

All photographic images used for editorial content have been licensed from the Associated Press.

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