Baltimore Orioles vs Oakland Athletics Prediction, Preview and Odds - 04/21/2022

Game Time: 3:37 pm ET, Thursday, April 21, 2022

Venue:  RingCentral Coliseum, Oakland, CA 

Where to Watch:  NBCS-CA

DraftKings:  Moneyline odds:  Orioles -115, Athletics -105; Over/Under:  7.5 runs

Bet365:  Moneyline odds:  Orioles +120, Athletics -145; Over/Under:  8 runs

BetMGM:  Moneyline odds:  Orioles +120, Athletics -145; Over/Under:  8 runs

 

Baltimore Orioles:  3-8 (5th place, AL East)

Oakland Athletics:  7-5 (2nd place, AL East)

 

Do not miss out on our expert handicapper analysis! Ben Burns has made $79.2K (10*) MLB! Make sure you check out his picks and many more from the expert handicappers featured in the Shop Picks section.

 

Baltimore Orioles:  3-7 last 10

Oakland Athletics:  7-3 last 10

 

 

 

The Orioles are coming into this game with a 3-8 record overall and they are 0-5 in their road games this season where they will be in this game. They have lost 3 of their last 4 games and are coming into this one on a 2 game losing streak. They just won their 3-game series against the New York Yankees 2-1 and they are playing the series finale of a 4-game series with the Athletics on Thursday night. This will be the 4th game of the series on Thursday with the 3rd game still to be played on Wednesday. Jordan Lyles is the starting pitcher for them on Wednesday while Tyler Wells will be on the mound for them here on Thursday. He is 0-1 with a 6.35 ERA this season. His team lost their last 2 games this season with him as a starter. In his last start, he allowed 0 ER, 0 HRs, and 2 BB with 3 Ks on 3 hits in 4 IP against the New York Yankees. They scored 9 runs in their last series averaging 3 runs scored per game in that span and they allowed 6 runs against them averaging 2 runs allowed per game.

 

The Athletics are coming into this game with a 7-5 record overall and they are 2-0 in their home games this season where they will be in this game. They have won 3 of their last 4 games and are coming into this one on a 2 game winning streak. They just lost their 3-game series against the Toronto Blue Jays 2-1 and they are playing the series finale of a 4-game series with the Orioles on Thursday night. This will be the 4th game of the series on Thursday with the 3rd game still to be played on Wednesday. Daulton Jefferies is the starter for them on Wednesday while Paul Blackburn will be throwing the first pitch for them here on Thursday. He is 1-0 with a 1.80 ERA this season. His team won their last 2 games with him as the starter. In his last start, he allowed 2 earned runs, 0 homers, and 0 BB with 3 strikeouts on 5 hits through 5 innings played against the Toronto Blue Jays. They scored 11 runs in their last series averaging just under 4 runs scored per game in that span and they allowed 13 runs against them averaging just over 4 runs allowed per game.

 

The Athletics are coming into this game as a slight favorite with the current betting odds according to Draftkings Sportsbook. They have been playing very well recently, already winning the first 2 games of this series and they have a solid starter on the mound in Blackburn here. He has had 2 great starts already and his team is going up against an Orioles team that has been struggling recently and has Wells on the mound who is not coming off of a good start in his last game. This is still the home opening series for the Athletics and they will be looking to take the series win against the orioles and possibly even a sweep depending on what they do on Wednesday. Regardless, the A's have been hitting the ball well recently despite all of their covid-19 absences and they have the better pitching matchup here. The best bet here is on the Athletics to win this game.

 

Orioles Athletics Prediction:  Our MLB Pick for Thursday, April 21, 2022 (3:37 pm ET start time) is Athletics 4 Orioles 1.

Don't miss our champion handicappers free picks and expert baseball picks today.  And if you enjoyed this Baltimore Orioles Oakland Athletics prediction, be sure to drop by every day for our daily MLB projections and previews.

 

 

Baltimore Orioles: 5-15 (-12.8 Units) ML when the money line is -100 to -150. 80-153 (-27.8 Units) ML in all games. 10-0 UNDER in all games.

Oakland Athletics: 49-42 (+5.1 Units) ML when the money line is +125 to -125. 68-48 (+4.4 Units) ML in home games. 24-17 UNDER against AL East opponents.

 

 

Baltimore Orioles:  J. Means (SP) Out indefinitely - Elbow injury. D. Kremer (SP) Out indefinitely - Oblique injury.

Oakland Athletics:  K. Snead (RP) Out indefinitely - Personal. A. Allen (C) Out indefinitely - Personal. S. Piscotty (RF) Out indefinitely - Illness.

 

 

 

"The first thing that came to my mind was that I had to get that ball. That's how I like to play. I play hard, I play with all my heart. The coaching staff and the players, they continue to trust me. They have the confidence in what I can do and it brings a lot of emotion." - Cristian Pache after their win against the Orioles on Tuesday night.

 

 

"Outstanding job by our bullpen again. The mentality down there is 27 outs and it kind of showed itself tonight. A really fun night for us overall. Didn't swing the bats great but we scored one more than they did, so good outcome." - Mark Kotsay on his team’s win against the Orioles on Tuesday.

 

 

 

 

Cedric Mullins (L) CF

Anthony Santander (S) LF

Ryan Mountcastle (R) 1B

Trey Mancini (R) DH

Austin Hays (R) RF

Ramon Urias (R) 2B

Robinson Chirinos (R) C

Kelvin Gutierrez (R) 3B

Jorge Mateo (R) SS

 

Tony Kemp (L) DH

Sheldon Neuse (R) 3B

Sean Murphy (R) C

Billy McKinney (L) RF

Christian Bethancourt (R) 1B

Elvis Andrus (R) SS

Seth Brown (L) LF

Cristian Pache (R) CF

Nick Allen (R) 2B

 

 

Batting Average:  Anthony Santander (.273)

Hits:  Ryan Mountcastle (11)

Home Runs:  Cedric Mullins (2)

RBI:  Cedric Mullins (8)

Stolen Bases:  Jorge Mateo (3)

Wins:  Mike Baumann (1)

Saves:  Jorge Lopez (1)

ERA:  Keegan Akin (0.00)

 

Batting Average:  Sheldon Neuse (.300)

Hits:  Sean Murphy (11)

Home Runs:  Chad Pinder (2)

RBI:  Seth Brown (11)

Stolen Bases:  Tony Kemp (2)

Wins:  Frankie Montas (2)

Saves:  Lou Trivino (2)

ERA:   Dany Jimenez (0.00)

 

Managers:

Baltimore Orioles: Brandon Hyde (4th season)

Oakland Athletics: Mark Kotsay (1st season)